C4BPA

Gene Name		complement component 4 binding protein, alpha
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Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Plasma Membrane Other Organism Cell Blood Microparticle
	Molecular Function	Protein Binding Poly(A) RNA Binding
	Biological Process	Complement Activation, Classical Pathway Regulation Of Complement Activation Innate Immune Response Positive Regulation Of Protein Catabolic Process Negative Regulation Of Complement Activation, Classical Pathway Regulation Of Opsonization
Pathways		Regulation of Complement cascade Complement cascade Innate Immune System
Drugs
Diseases
GWAS		C4b binding protein levels ( 20212171)
Protein-protein Interactions		9 interactors: APCS BMPR2 FXYD6 GIT2 GTF2I LBP LRP1 PROS1 SMARCD1
Entrez ID		722
HPRD ID		00403
Ensembl ID		ENSG00000123838
Uniprot IDs		P04003 Q5VVQ8
PDB IDs		2A55 4B0F
Enriched GO Terms of Interacting Partners?		Regulation Of Locomotion Acute-phase Response Regulation Of Inflammatory Response Artery Development Negative Regulation Of Wound Healing Regulation Of Acute Inflammatory Response Acute Inflammatory Response Beta-amyloid Clearance Regulation Of Metabolic Process Positive Regulation Of Chemotaxis Positive Regulation Of Respiratory Burst Involved In Inflammatory Response Leukocyte Chemotaxis Involved In Inflammatory Response Negative Regulation By Host Of Viral Exo-alpha-sialidase Activity Negative Regulation By Host Of Viral Glycoprotein Metabolic Process Regulation Of Lung Blood Pressure Lipopolysaccharide Transport Transition Between Slow And Fast Fiber Negative Regulation Of Exo-alpha-sialidase Activity Negative Regulation Of Chondrocyte Proliferation Positive Regulation Of Behavior Regulation Of Wound Healing Negative Regulation Of Vasoconstriction Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Regulation Of Cell Migration Regulation Of Chemotaxis Regulation Of Cell Motility Regulation Of Cellular Component Movement Regulation Of Behavior Negative Regulation Of Monocyte Differentiation Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Innate Immune Response Positive Regulation Of Respiratory Burst Leukocyte Migration Positive Regulation Of Axon Extension Involved In Axon Guidance Regulation Of Skeletal Muscle Adaptation Lymphatic Endothelial Cell Differentiation Negative Regulation Of Cytosolic Calcium Ion Concentration Negative Regulation Of Growth Negative Regulation Of Locomotion Phagocytosis Chromatin-mediated Maintenance Of Transcription Opsonization Regulation Of Respiratory Burst Macrophage Activation Involved In Immune Response Regulation Of Phospholipase A2 Activity Positive Regulation Of Macrophage Activation Lymphangiogenesis Response To Stress Positive Regulation Of Toll-like Receptor Signaling Pathway Negative Regulation Of Glycoprotein Metabolic Process
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