ASPM

Gene Name		asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Midbody Meiotic Spindle Mitotic Spindle Pole
	Molecular Function	Calmodulin Binding
	Biological Process	Neuron Migration Positive Regulation Of Neuroblast Proliferation Mitotic Nuclear Division Spermatogenesis Male Gonad Development Forebrain Neuroblast Division Cerebral Cortex Development Negative Regulation Of Neuron Differentiation Negative Regulation Of Asymmetric Cell Division Oogenesis Developmental Growth Maintenance Of Centrosome Location Positive Regulation Of Canonical Wnt Signaling Pathway Spindle Assembly Involved In Meiosis Neuronal Stem Cell Maintenance
Pathways
Drugs
Diseases
GWAS		Age-related macular degeneration ( 23536807)
Protein-protein Interactions		2 interactors: LIG4 PLK1
Entrez ID		259266
HPRD ID		08384
Ensembl ID		ENSG00000066279
Uniprot IDs		B3KWI2 Q8IZT6
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA Ligation Involved In DNA Recombination Activation Of APC-Cdc20 Complex Activity Polar Body Extrusion After Meiotic Divisions Cell Division Lagging Strand Elongation Pro-B Cell Differentiation Activation Of Anaphase-promoting Complex Activity Meiotic Cytokinesis Positive Regulation Of Mitotic Metaphase/anaphase Transition Establishment Of Integrated Proviral Latency Metaphase/anaphase Transition Of Mitotic Cell Cycle Immunoglobulin V(D)J Recombination Establishment Of Viral Latency T Cell Receptor V(D)J Recombination DNA Ligation Involved In DNA Repair Protein Localization To Chromatin Lymphoid Progenitor Cell Differentiation Cell Proliferation DNA Ligation Cellular Response To DNA Damage Stimulus Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Chromosome Segregation Nucleotide-excision Repair, DNA Gap Filling Cellular Response To Lithium Ion Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death Single Strand Break Repair Double-strand Break Repair Via Nonhomologous End Joining Chromosome Organization Protein Destabilization Isotype Switching Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity V(D)J Recombination DNA Strand Elongation Involved In DNA Replication Protein Localization To Chromosome Response To Lithium Ion DNA Strand Elongation Response To X-ray G2 DNA Damage Checkpoint Mitotic Spindle Assembly Checkpoint Somatic Recombination Of Immunoglobulin Gene Segments Mitotic Nuclear Envelope Disassembly Spindle Assembly Checkpoint Female Meiotic Division Somatic Diversification Of Immunoglobulins Mitotic Spindle Checkpoint Cell Cycle Positive Regulation Of Mitotic Nuclear Division Negative Regulation Of Chromosome Segregation
Tagcloud ?		0x 1x adamts13 atp6v0a2 bioinformatic bl chickens col12a1 fowl grm5 interpretations jungle lrp2 obscn plau ppp1ca prkdc resequencing rnf168 sanger sl slv smyth stab2 ubc ubiquitinylation vitiliginous vitiligo xirp1