PLIN1 and ABHD5

Number of citations of the paper that reports this interaction (PMID 15136565)
58

Data Source:
HPRD (in vitro, two hybrid)

		PLIN1	ABHD5
Gene Name		perilipin 1	abhydrolase domain containing 5
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Lipid Particle Cytosol	Nucleus Cytoplasm Lipid Particle Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Lipid Binding	1-acylglycerol-3-phosphate O-acyltransferase Activity Triglyceride Lipase Activity Lysophosphatidic Acid Acyltransferase Activity
	Biological Process	Lipid Metabolic Process Triglyceride Catabolic Process Small Molecule Metabolic Process	Fatty Acid Metabolic Process Phosphatidic Acid Biosynthetic Process Negative Regulation Of Sequestering Of Triglyceride Positive Regulation Of Triglyceride Catabolic Process Triglyceride Catabolic Process Cell Differentiation Small Molecule Metabolic Process Positive Regulation Of Lipoprotein Lipase Activity
Pathways		Metabolism of lipids and lipoproteins Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis Transcriptional regulation of white adipocyte differentiation Lipid digestion, mobilization, and transport	Metabolism of lipids and lipoproteins Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis Lipid digestion, mobilization, and transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: ABHD5 LIPE PRKACA	3 interactors: PLIN1 PLIN2 PNPLA2
Entrez ID		5346	51099
HPRD ID		01364	11986
Ensembl ID		ENSG00000166819
Uniprot IDs		O60240	Q8WTS1
PDB IDs
Enriched GO Terms of Interacting Partners?		Triglyceride Catabolic Process Acylglycerol Catabolic Process Triglyceride Metabolic Process Neutral Lipid Metabolic Process Cellular Lipid Catabolic Process Lipid Catabolic Process Glycerolipid Metabolic Process Positive Regulation Of Lipase Activity Cellular Lipid Metabolic Process Positive Regulation Of Dense Core Granule Biogenesis Lipid Metabolic Process Histone H3-T6 Phosphorylation Diacylglycerol Catabolic Process Catabolic Process Fatty Acid Metabolic Process Negative Regulation Of Sequestering Of Triglyceride Peptidyl-serine Autophosphorylation Long-chain Fatty Acid Catabolic Process Positive Regulation Of Triglyceride Catabolic Process Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Cellular Response To Parathyroid Hormone Stimulus Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Small Molecule Metabolic Process Desmosome Assembly Negative Regulation Of Glial Cell Apoptotic Process Regulation Of Tight Junction Assembly Negative Regulation Of Glucose Import Positive Regulation Of Macrophage Differentiation Positive Regulation Of Lipoprotein Lipase Activity Cell Communication By Electrical Coupling Involved In Cardiac Conduction Response To Parathyroid Hormone Calcium-mediated Signaling Using Intracellular Calcium Source Desmosome Organization Positive Regulation Of Protein Export From Nucleus Monocarboxylic Acid Metabolic Process Cell Communication By Electrical Coupling Phosphate-containing Compound Metabolic Process Activation Of Protein Kinase A Activity Regulation Of Platelet Aggregation Negative Regulation Of Lipid Storage Negative Regulation Of Glucose Transport Sperm Capacitation Diacylglycerol Metabolic Process Cellular Response To Epinephrine Stimulus Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Induction Of Positive Chemotaxis Positive Regulation Of Cardiac Muscle Hypertrophy Response To Epinephrine Positive Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Lipopolysaccharide-mediated Signaling Pathway	Triglyceride Catabolic Process Acylglycerol Catabolic Process Lipid Storage Triglyceride Metabolic Process Neutral Lipid Metabolic Process Cellular Lipid Metabolic Process Cellular Lipid Catabolic Process Lipid Metabolic Process Lipid Catabolic Process Lipid Localization Acylglycerol Acyl-chain Remodeling Glycerolipid Metabolic Process Negative Regulation Of Sequestering Of Triglyceride Small Molecule Metabolic Process Positive Regulation Of Triglyceride Catabolic Process Lipid Particle Organization Negative Regulation Of Lipid Storage Positive Regulation Of Lipid Catabolic Process Regulation Of Triglyceride Metabolic Process Long-chain Fatty Acid Transport Regulation Of Lipid Catabolic Process Regulation Of Lipid Storage Fatty Acid Transport Catabolic Process Monocarboxylic Acid Transport
Tagcloud ?		3t3l1 adipogenesis canonical dickkopf disrupted dkk1 droplet droplets ebps fewer fzds k146q lef1 mutants ncor ncordeltaid perilipin ppargamma ppargamma2 preadiocytes preadipocyte preadipocytes recruit rescued sumoylation tr tralpha trbeta wnt	adenomatous aerobic ampkalpha apc attributable cgi comparative correlates crc crcs deficiency enhances falls glycolysis hydrolase intestine knockout link lipolysis lipolytic malignancies malignant mesenchymal polyps robustly shift substantially suppressing transformation
Tagcloud (Difference) ?		3t3l1 adipogenesis canonical dickkopf disrupted dkk1 droplet droplets ebps fewer fzds k146q lef1 mutants ncor ncordeltaid perilipin ppargamma ppargamma2 preadiocytes preadipocyte preadipocytes recruit rescued sumoylation tr tralpha trbeta wnt	adenomatous aerobic ampkalpha apc attributable cgi comparative correlates crc crcs deficiency enhances falls glycolysis hydrolase intestine knockout link lipolysis lipolytic malignancies malignant mesenchymal polyps robustly shift substantially suppressing transformation
Tagcloud (Intersection) ?