MAGEA11 and DNAJC10

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		MAGEA11	DNAJC10
Description		MAGE family member A11	DnaJ heat shock protein family (Hsp40) member C10
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Membrane Endoplasmic Reticulum Chaperone Complex
	Molecular Function	Protein Binding Histone Deacetylase Binding	ATPase Activator Activity Protein Binding Protein-disulfide Reductase Activity Disulfide Oxidoreductase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On A Sulfur Group Of Donors, Disulfide As Acceptor Hsp70 Protein Binding Protein-folding Chaperone Binding ATPase Binding Misfolded Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II	Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress IRE1-mediated Unfolded Protein Response ERAD Pathway Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
Pathways
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Night sleep phenotypes ( 27126917) Pulmonary arterial hypertension ( 29088834) Waist-to-hip circumference ratio (dietary energy interaction) ( 23192594)
Interacting Genes		115 interacting genes: ACMSD ACSM2B ACTN1 AKR1C3 ALDH5A1 AR ARHGAP29 BCL2L11 BEX2 BIRC2 BRD1 C18orf54 C22orf39 CASP7 CAVIN3 CCDC106 CCDC14 CCDC146 CCDC185 CCDC27 CCNA2 CDC20B CDKN2B CEP76 CLUAP1 CORO1A COX7A2L CSNK2A1 CTTNBP2 DLGAP1 DNAJC10 DOCK10 ENOX2 EWSR1 FAM156A FAM161A FBXO46 GADD45GIP1 GCSH GNPDA1 HOXB5 IFI44 IL11 IL6ST ILF3 JADE3 KIAA0408 LMBR1L LNX1 MAPK3 MCRS1 MED28 MGME1 MLF1 MTA1 MXD3 MYOZ1 NCOA2 NDEL1 NDUFAF1 NDUFB9 NIF3L1 NOL4 NOS3 NSUN4 NTAQ1 OTUB2 PCBD2 PCF11 PDE4B PHYH PIK3IP1 PIN4 PLCXD3 PNKD PNKP POLR1D PPIF PPM1K PRDX3 PRKRIP1 PSMF1 RADIL RANBP10 RBM23 REX1BD SH2D4A SNX20 SNX7 SPMIP9 STAR SUCLA2 SUOX SUV39H2 TCEA2 TCEANC TCF25 TEKTL1 THEM5 TMEM123 TPM3 TRIM27 TRIM51 TRMT1 TXN2 UBE2D4 UBE3D USP20 UTP25 VTA1 WTAP ZBTB16 ZCCHC12 ZNF655 ZSWIM2	4 interacting genes: HSPA5 MAGEA11 PTEN SQSTM1
Entrez ID		4110	54431
HPRD ID		02281	09722
Ensembl ID		ENSG00000185247	ENSG00000077232
Uniprot IDs		G5E962 P43364	Q8IXB1
PDB IDs		6WJH
Enriched GO Terms of Interacting Partners?		Mitochondrial Matrix Protein Binding Mitochondrion Catabolic Process	Positive Regulation Of Biosynthetic Process Regulation Of Protein Folding Enzyme Binding Maintenance Of Protein Localization In Endoplasmic Reticulum Regulation Of Cellular Component Organization PERK-mediated Unfolded Protein Response ER Overload Response Regulation Of Protein Ubiquitination Post-translational Protein Targeting To Membrane, Translocation Cerebellum Structural Organization Regulation Of Macromolecule Biosynthetic Process Endoplasmic Reticulum Chaperone Complex Negative Regulation Of PERK-mediated Unfolded Protein Response IRE1-mediated Unfolded Protein Response Regulation Of Protein Modification Process Regulation Of Post-translational Protein Modification Regulation Of Macromolecule Metabolic Process Cerebellar Purkinje Cell Layer Development Ubiquitin Protein Ligase Binding Regulation Of Gene Expression Regulation Of Transcription By RNA Polymerase II Protein Folding In Endoplasmic Reticulum Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of ATF6-mediated Unfolded Protein Response Regulation Of Protein Folding In Endoplasmic Reticulum Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of IRE1-mediated Unfolded Protein Response Locomotor Rhythm Negative Regulation Of Synaptic Vesicle Clustering Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Cellular Response To Electrical Stimulus Ubiquitin Ligase Activator Activity Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Spindle Assembly Involved In Female Meiosis Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Negative Regulation Of Peptidyl-serine Phosphorylation Regulation Of Synaptic Vesicle Clustering PML Body Postsynaptic Specialization Assembly Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Neuron-neuron Synaptic Transmission Phosphatidylinositol Phosphate Phosphatase Activity Central Nervous System Myelin Maintenance Negative Regulation Of Cell Size Presynaptic Membrane Organization Schmidt-Lanterman Incisure Rhythmic Synaptic Transmission Anaphase-promoting Complex Binding
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