MAGEA11 and UBE3D

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MAGEA11	UBE3D
Description		MAGE family member A11	ubiquitin protein ligase E3D
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Body	Ubiquitin Ligase Complex Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding Histone Deacetylase Binding	Protein Binding Ribonuclease Inhibitor Activity Transferase Activity Cyclin Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin-like Protein Conjugating Enzyme Binding Ubiquitin Protein Ligase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II	Protein Polyubiquitination Protein Monoubiquitination Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Adult body size ( 32376654) Crohn's disease ( 26891255) Entorhinal cortical volume ( 31530798) Heel bone mineral density ( 28869591 30598549) Schizophrenia, bipolar disorder or recurrent major depressive disorder ( 34099189)
Interacting Genes		115 interacting genes: ACMSD ACSM2B ACTN1 AKR1C3 ALDH5A1 AR ARHGAP29 BCL2L11 BEX2 BIRC2 BRD1 C18orf54 C22orf39 CASP7 CAVIN3 CCDC106 CCDC14 CCDC146 CCDC185 CCDC27 CCNA2 CDC20B CDKN2B CEP76 CLUAP1 CORO1A COX7A2L CSNK2A1 CTTNBP2 DLGAP1 DNAJC10 DOCK10 ENOX2 EWSR1 FAM156A FAM161A FBXO46 GADD45GIP1 GCSH GNPDA1 HOXB5 IFI44 IL11 IL6ST ILF3 JADE3 KIAA0408 LMBR1L LNX1 MAPK3 MCRS1 MED28 MGME1 MLF1 MTA1 MXD3 MYOZ1 NCOA2 NDEL1 NDUFAF1 NDUFB9 NIF3L1 NOL4 NOS3 NSUN4 NTAQ1 OTUB2 PCBD2 PCF11 PDE4B PHYH PIK3IP1 PIN4 PLCXD3 PNKD PNKP POLR1D PPIF PPM1K PRDX3 PRKRIP1 PSMF1 RADIL RANBP10 RBM23 REX1BD SH2D4A SNX20 SNX7 SPMIP9 STAR SUCLA2 SUOX SUV39H2 TCEA2 TCEANC TCF25 TEKTL1 THEM5 TMEM123 TPM3 TRIM27 TRIM51 TRMT1 TXN2 UBE2D4 UBE3D USP20 UTP25 VTA1 WTAP ZBTB16 ZCCHC12 ZNF655 ZSWIM2	5 interacting genes: CCNB1 MAGEA11 PCNA TRIM28 UBE2C
Entrez ID		4110	90025
HPRD ID		02281	12861
Ensembl ID		ENSG00000185247	ENSG00000118420
Uniprot IDs		G5E962 P43364	D6RD24 Q4G0J6 Q4G0X5 Q7Z6J8
PDB IDs		6WJH
Enriched GO Terms of Interacting Partners?		Mitochondrial Matrix Protein Binding Mitochondrion Catabolic Process	Ubiquitin-like Protein Ligase Binding Cellular Response To Iron(III) Ion Positive Regulation Of Mitotic Cell Cycle Phase Transition Response To DDT Regulation Of Sister Chromatid Segregation Cyclin B1-CDK1 Complex Positive Regulation Of Cell Cycle Phase Transition Regulation Of Chromosome Segregation Positive Regulation Of Mitotic Cell Cycle Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Sister Chromatid Separation Regeneration Regulation Of Chromosome Separation PCNA Complex PCNA-p21 Complex Replisome DNA Polymerase Processivity Factor Activity Purine-specific Mismatch Base Pair DNA N-glycosylase Activity Krueppel-associated Box Domain Binding Nucleoplasm Positive Regulation Of DNA Repair Regulation Of Nuclear Division Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Telomere Maintenance Via Semi-conservative Replication Dinucleotide Insertion Or Deletion Binding Ubiquitin-like Protein Ligase Activity Response To Iron(III) Ion Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport Positive Regulation Of Deoxyribonuclease Activity Leading Strand Elongation Embryonic Placenta Morphogenesis Positive Regulation Of Exit From Mitosis Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of MRNA 3'-end Processing Response To Insecticide Regulation Of Primary Metabolic Process Regulation Of Chromosome Organization Chordate Embryonic Development In Utero Embryonic Development Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA Repair MutLalpha Complex Binding Telomere Maintenance Via Semi-conservative Replication Convergent Extension Involved In Axis Elongation Chromo Shadow Domain Binding Positive Regulation Of Ubiquitin Protein Ligase Activity Free Ubiquitin Chain Polymerization
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