ATP6V0C and TMEM31

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ATP6V0C	TMEM31
Description		ATPase H+ transporting V0 subunit c	transmembrane protein 31
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Vacuolar Proton-transporting V-type ATPase, V0 Domain Lysosomal Membrane Plasma Membrane Focal Adhesion Endosome Membrane Membrane Clathrin-coated Vesicle Membrane Phagocytic Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Proton-transporting V-type ATPase Complex Proton-transporting Two-sector ATPase Complex, Proton-transporting Domain Proton-transporting V-type ATPase, V0 Domain Azurophil Granule Membrane Synapse Extracellular Exosome Tertiary Granule Membrane Bounding Membrane Of Organelle Ficolin-1-rich Granule Membrane	Membrane
	Molecular Function	Protein Binding Proton Transmembrane Transporter Activity Ubiquitin Protein Ligase Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Proton-transporting ATPase Activity, Rotational Mechanism	Protein Binding
	Biological Process	Monoatomic Ion Transport Vacuolar Acidification Lysosomal Lumen Acidification Proton Motive Force-driven ATP Synthesis Regulation Of Macroautophagy Positive Regulation Of Wnt Signaling Pathway Endosomal Lumen Acidification Intracellular PH Reduction Golgi Lumen Acidification Synaptic Vesicle Lumen Acidification Proton Transmembrane Transport
Pathways		ROS and RNS production in phagocytes Neutrophil degranulation Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy
Drugs		Tiludronic acid
Diseases
GWAS
Interacting Genes		54 interacting genes: AQP6 ARF6 ASGR2 CD53 CD69 CD79A CERS2 CLEC14A CLEC17A CLEC2D CLIC1 CPLX4 CREB3 DNAJC1 DRD2 EDA EDA2R ERBB2 ERGIC3 ERH EVI2A FAM210B FFAR2 GPR152 GPR25 GPR42 HSD17B13 HTR2C KLRC1 LMNA LRRC25 MARK3 MCEMP1 MDFI MSR1 NIPAL3 OPRM1 PDCD1LG2 PI16 PSMA3 RETREG3 SCN3B SLC35E3 SLC7A1 SMIM3 SPACA1 SSMEM1 STOM SUSD3 TMEM139 TMEM31 TMEM9 VSIR ZCCHC12	138 interacting genes: ABHD16A ABHD5 AGPAT4 AGTRAP ANKRD46 APOD ARV1 ATP6V0C BCAP31 BLCAP BMP10 BNIP1 BTN2A2 C14orf180 C2CD2L CAMLG CCL4 CGRRF1 CLDND2 CLN5 CLRN1 CMTM7 CNIH3 COX14 COX20 CTSA CTXN3 CXCL9 CXorf66 CYB561A3 CYB5R3 DEFB103A DEFB103B DEFB105A DEFB105B DERL1 DERL3 DGAT2L6 DHRSX DNAJC30 EBP EHHADH EMP1 ERG28 FAXDC2 FCER1G FKBP8 FXYD6 GIMAP5 GJB2 GJD4 GPR151 GUCA2A GYPA HERPUD2 HIGD1C HSD17B13 HSD3B7 IFITM5 ITGAM LHFPL5 LPAR3 LRAT LY6D MALL MMP14 MS4A1 NAT8 NINJ1 NINJ2 NSDHL ORMDL2 OTOP3 OTULINL PEDS1-UBE2V1 PLN PLP1 PLP2 PMP22 PNLIPRP1 PTPN1 RDH11 REEP2 RETREG3 RNF144A RNF19B RTP2 SELENOK SELENOM SERP2 SGTA SLC30A8 SLC35E4 SLC35H1 SLC39A6 SLC41A1 SLC66A2 SLC71A2 SLC7A14 SMAGP SMIM1 SMIM3 SMPD2 SNORC SPTSSA STX12 STX5 SYNGR1 TEX264 TIMMDC1 TMBIM6 TMEM107 TMEM121 TMEM14A TMEM14C TMEM182 TMEM203 TMEM208 TMEM218 TMEM239 TMEM242 TMEM254 TMEM255B TMEM44 TMEM50A TMEM86A TMX2 TNFRSF10B TRARG1 TSPAN2 TVP23B UBE2J1 VAMP2 VAMP3 VAMP5 YIF1A YIPF6 ZFPL1
Entrez ID		527	203562
HPRD ID		00162	06652
Ensembl ID		ENSG00000185883	ENSG00000179363
Uniprot IDs		P27449	A0A140VK58 Q5JXX7
PDB IDs		6WLW 6WM2 6WM3 6WM4 7U4T 7UNF
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Plasma Membrane Transmembrane Signaling Receptor Activity External Side Of Plasma Membrane Carbohydrate Binding G Protein-coupled Receptor Activity Fucose Binding Regulation Of Establishment Of Protein Localization Identical Protein Binding	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Protein Binding Sterol Biosynthetic Process Lipid Biosynthetic Process Response To Endoplasmic Reticulum Stress Steroid Biosynthetic Process SNAP Receptor Activity Lipid Droplet Lipid Metabolic Process Endoplasmic Reticulum Unfolded Protein Response SNARE Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Bleb Assembly Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Mitochondrial Membrane Regulation Of Retrograde Protein Transport, ER To Cytosol Organelle Membrane Fusion Cholesterol Biosynthetic Process 3-beta-hydroxy-Delta5-steroid Dehydrogenase (NAD+) Activity Establishment Of Protein Localization To Membrane Regulation Of Cellular Localization Regulation Of Intracellular Transport Membrane Destabilizing Activity Cellular Response To Unfolded Protein Endoplasmic Reticulum-Golgi Intermediate Compartment Sterol Metabolic Process Mitochondrial Respiratory Chain Complex Assembly Organelle Fusion Response To Unfolded Protein Regulation Of Protein Exit From Endoplasmic Reticulum Membrane Organization
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?