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TMEM31 and GUCA2A
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
TMEM31
GUCA2A
Description
transmembrane protein 31
guanylate cyclase activator 2A
Image
No pdb structure
GO Annotations
Cellular Component
Membrane
Extracellular Region
Molecular Function
Protein Binding
Hormone Activity
Protein Binding
Guanylate Cyclase Activator Activity
Biological Process
Signal Transduction
Pathways
Digestion
Drugs
Diseases
GWAS
Interacting Genes
138 interacting genes:
ABHD16A
ABHD5
AGPAT4
AGTRAP
ANKRD46
APOD
ARV1
ATP6V0C
BCAP31
BLCAP
BMP10
BNIP1
BTN2A2
C14orf180
C2CD2L
CAMLG
CCL4
CGRRF1
CLDND2
CLN5
CLRN1
CMTM7
CNIH3
COX14
COX20
CTSA
CTXN3
CXCL9
CXorf66
CYB561A3
CYB5R3
DEFB103A
DEFB103B
DEFB105A
DEFB105B
DERL1
DERL3
DGAT2L6
DHRSX
DNAJC30
EBP
EHHADH
EMP1
ERG28
FAXDC2
FCER1G
FKBP8
FXYD6
GIMAP5
GJB2
GJD4
GPR151
GUCA2A
GYPA
HERPUD2
HIGD1C
HSD17B13
HSD3B7
IFITM5
ITGAM
LHFPL5
LPAR3
LRAT
LY6D
MALL
MMP14
MS4A1
NAT8
NINJ1
NINJ2
NSDHL
ORMDL2
OTOP3
OTULINL
PEDS1-UBE2V1
PLN
PLP1
PLP2
PMP22
PNLIPRP1
PTPN1
RDH11
REEP2
RETREG3
RNF144A
RNF19B
RTP2
SELENOK
SELENOM
SERP2
SGTA
SLC30A8
SLC35E4
SLC35H1
SLC39A6
SLC41A1
SLC66A2
SLC71A2
SLC7A14
SMAGP
SMIM1
SMIM3
SMPD2
SNORC
SPTSSA
STX12
STX5
SYNGR1
TEX264
TIMMDC1
TMBIM6
TMEM107
TMEM121
TMEM14A
TMEM14C
TMEM182
TMEM203
TMEM208
TMEM218
TMEM239
TMEM242
TMEM254
TMEM255B
TMEM44
TMEM50A
TMEM86A
TMX2
TNFRSF10B
TRARG1
TSPAN2
TVP23B
UBE2J1
VAMP2
VAMP3
VAMP5
YIF1A
YIPF6
ZFPL1
15 interacting genes:
ASPH
FFAR2
GJA8
GOLM1
GUCY2C
NEMP1
SGTA
SLC34A2
TMEM179B
TMEM237
TMEM31
TMEM86B
TRAM1
UBQLN1
UBQLN2
Entrez ID
203562
2980
HPRD ID
06652
00767
Ensembl ID
ENSG00000179363
ENSG00000197273
Uniprot IDs
A0A140VK58
Q5JXX7
Q02747
PDB IDs
1GNA
1GNB
1O8R
Enriched GO Terms of Interacting Partners
?
Membrane
Endoplasmic Reticulum Membrane
Endoplasmic Reticulum
Protein Binding
Sterol Biosynthetic Process
Lipid Biosynthetic Process
Response To Endoplasmic Reticulum Stress
Steroid Biosynthetic Process
SNAP Receptor Activity
Lipid Droplet
Lipid Metabolic Process
Endoplasmic Reticulum Unfolded Protein Response
SNARE Complex
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Bleb Assembly
Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
Mitochondrial Membrane
Regulation Of Retrograde Protein Transport, ER To Cytosol
Organelle Membrane Fusion
Cholesterol Biosynthetic Process
3-beta-hydroxy-Delta5-steroid Dehydrogenase (NAD+) Activity
Establishment Of Protein Localization To Membrane
Regulation Of Cellular Localization
Regulation Of Intracellular Transport
Membrane Destabilizing Activity
Cellular Response To Unfolded Protein
Endoplasmic Reticulum-Golgi Intermediate Compartment
Sterol Metabolic Process
Mitochondrial Respiratory Chain Complex Assembly
Organelle Fusion
Response To Unfolded Protein
Regulation Of Protein Exit From Endoplasmic Reticulum
Membrane Organization
Membrane
Positive Regulation Of ERAD Pathway
Regulation Of ERAD Pathway
Positive Regulation Of Response To Endoplasmic Reticulum Stress
Positive Regulation Of Proteolysis
Regulation Of Response To Endoplasmic Reticulum Stress
ERAD Pathway
Positive Regulation Of Proteasomal Protein Catabolic Process
Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
Regulation Of Proteolysis
Protein Insertion Into ER Membrane
Polyubiquitin Modification-dependent Protein Binding
Regulation Of Proteasomal Protein Catabolic Process
Positive Regulation Of Protein Catabolic Process
Negative Regulation Of Store-operated Calcium Channel Activity
D-lysine 5,6-aminomutase Activity
Response To Endoplasmic Reticulum Stress
Peptidyl-aspartic Acid 3-dioxygenase Activity
Plasma Membrane
Positive Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus
Protein Targeting To Membrane
TRC Complex
Protein Insertion Into Membrane
Negative Regulation Of G Protein-coupled Receptor Internalization
Ether Hydrolase Activity
Alkenylglycerophosphocholine Hydrolase Activity
Regulation Of Transmembrane Transporter Activity
Regulation Of Monoatomic Ion Transmembrane Transporter Activity
Autophagosome
Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity
Negative Regulation Of Toll-like Receptor 3 Signaling Pathway
Autophagosome Assembly
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Tagcloud (Intersection)
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