AVPI1 and EMD

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		AVPI1	EMD
Description		arginine vasopressin induced 1	emerin
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Nucleoplasm Cytoplasm Endoplasmic Reticulum Spindle Cytosol Microtubule Membrane Spindle Pole Centrosome Nuclear Membrane Cortical Endoplasmic Reticulum TMEM240-body
	Molecular Function	Protein Binding	Actin Binding Protein Binding Cadherin Binding Beta-tubulin Binding
	Biological Process	Positive Regulation Of MAPK Cascade	Muscle Contraction Muscle Organ Development Skeletal Muscle Cell Differentiation Positive Regulation Of Protein Export From Nucleus Negative Regulation Of Fibroblast Proliferation Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Growth Factor Stimulus Nuclear Membrane Organization Negative Regulation Of Canonical Wnt Signaling Pathway Amyloid Fibril Formation
Pathways			Nuclear Envelope Breakdown Initiation of Nuclear Envelope (NE) Reformation Depolymerization of the Nuclear Lamina RAC1 GTPase cycle RAC2 GTPase cycle RHOD GTPase cycle RHOG GTPase cycle RAC3 GTPase cycle Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases			Emery-Dreifuss muscular dystrophy
GWAS			Mean spheric corpuscular volume ( 32888494)
Interacting Genes		34 interacting genes: AIRIM APP CABP2 CDCA7L CYSRT1 DGCR6L EMD ENKD1 GOLGA6L9 IKBKG KRT31 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP4-2 LMO3 LONRF1 MDFI MKRN3 PHF1 PICK1 POLR1C PPP1R16A PRKAA2 PRKACA PRKACB RIPPLY1 RIPPLY2 SCNM1	100 interacting genes: ABL1 ABT1 ACTB ACTG2 AEN AKAP8L ANK1 ANKS6 AQP6 AVPI1 BANF1 BCLAF1 BEND7 BYSL CATSPER1 CCDC33 CCNL2 CD33 CEP70 CERS4 CISD2 CLEC14A COMT COPS6 CPLX4 CREB3 CTNNBIP1 CXorf66 DPPA4 EFHC2 ERMAP FAM209A FATE1 GMCL1 GOLM2 GORAB GPR152 GRAMD2A HSF2BP INCA1 KASH5 KCNJ12 KCNJ18 KCNJ8 KCNN3 KIF9 KIR2DL3 LIME1 LMNA LMO7 LPL LUZP4 MAB21L3 MAPK6 MEOX1 MEOX2 MMGT1 MRPL45 MTERF4 MTNR1A NCAPH2 NF2 NPDC1 PAK5 PIMREG PSME1 REL RNASEH1 RNF123 SH3GL2 SH3GL3 SLC10A1 SLC35H1 SOWAHB SRC SSMEM1 STX1A SYNE1 TCF23 TMEM174 TMEM200A TMEM201 TMEM52B TMEM80 TMX2 TRAF3IP3 TRIM42 VAV1 WEE2-AS1 YTHDC1 ZFP1 ZFP57 ZFP64 ZNF165 ZNF232 ZNF329 ZNF341 ZNF398 ZNF549 ZNF774
Entrez ID		60370	2010
HPRD ID		16530	02309
Ensembl ID		ENSG00000119986	ENSG00000102119
Uniprot IDs		Q5T686	P50402
PDB IDs			1JEI 2ODC 2ODG 6GHD 6RPR 7NDY
Enriched GO Terms of Interacting Partners?		Keratin Filament Intermediate Filament Protein Localization To Lipid Droplet Cytosol CAMP-dependent Protein Kinase Activity Regulation Of Glycolytic Process CAMP-dependent Protein Kinase Complex Ciliary Base High-density Lipoprotein Particle Assembly Vascular Endothelial Cell Response To Laminar Fluid Shear Stress Somite Rostral/caudal Axis Specification Nucleotide-activated Protein Kinase Complex Regulation Of Carbohydrate Catabolic Process Negative Regulation Of TORC1 Signaling TORC1 Signaling Vascular Endothelial Cell Response To Fluid Shear Stress Regulation Of ATP Metabolic Process Axis Specification Regulation Of Purine Nucleotide Metabolic Process TOR Signaling Cellular Response To Laminar Fluid Shear Stress Renal Water Homeostasis Positive Regulation Of Protein Export From Nucleus Negative Regulation Of TOR Signaling Positive Regulation Of Glycolytic Process Response To Laminar Fluid Shear Stress Plasma Lipoprotein Particle Assembly Regulation Of TORC1 Signaling Protein-lipid Complex Assembly Positive Regulation Of Receptor Internalization Protein Serine/threonine/tyrosine Kinase Activity Multicellular Organismal-level Water Homeostasis Amyloid Fibril Formation Cellular Response To Nutrient Levels Embryonic Axis Specification Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Identical Protein Binding TMEM240-body Cellular Response To Fluid Shear Stress Negative Regulation Of Signaling Negative Regulation Of Cell Communication	Protein Binding Inward Rectifier Potassium Channel Activity Fc-gamma Receptor Signaling Pathway
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