PEX12 and PEX10

Number of citations of the paper that reports this interaction (PMID 10562279)
21

Data Source:
BioGRID (two hybrid)
HPRD (in vitro, in vivo, two hybrid)

		PEX12	PEX10
Gene Name		peroxisomal biogenesis factor 12	peroxisomal biogenesis factor 10
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane	Intracellular Peroxisome Peroxisomal Membrane Integral Component Of Peroxisomal Membrane
	Molecular Function	Protein Binding Protein C-terminus Binding Zinc Ion Binding	Protein Binding Protein C-terminus Binding Zinc Ion Binding
	Biological Process	Protein Targeting To Peroxisome Peroxisome Organization Protein Import Into Peroxisome Matrix	Peroxisome Organization Protein Import Into Peroxisome Matrix
Pathways
Drugs
Diseases
GWAS			Non-obstructive azoospermia ( 22197933)
Protein-Protein Interactions		3 interactors: PEX10 PEX19 PEX5	10 interactors: CGRRF1 HNRNPD LIG4 MKRN3 PCGF6 PEX12 PEX19 PEX2 PEX5 UBE2I
Entrez ID		5193	5192
HPRD ID		03455	04175
Ensembl ID		ENSG00000108733	ENSG00000157911
Uniprot IDs		O00623	O60683
PDB IDs
Enriched GO Terms of Interacting Partners?		Establishment Of Protein Localization To Peroxisome Protein Targeting To Peroxisome Peroxisome Organization Intracellular Protein Transmembrane Transport Protein Transmembrane Transport Protein Import Into Peroxisome Membrane Protein Import Peroxisomal Membrane Transport Protein Import Into Peroxisome Matrix Establishment Of Protein Localization To Organelle Protein Targeting Protein Localization To Organelle Cytoplasmic Transport Intracellular Protein Transport Negative Regulation Of Lipid Binding Protein Targeting To Membrane Cellular Protein Localization Protein Transport Negative Regulation Of Protein Homotetramerization Establishment Of Protein Localization Intracellular Transport Establishment Of Protein Localization To Membrane Protein Import Into Peroxisome Matrix, Translocation Transmembrane Transport Peroxisome Membrane Biogenesis Protein Import Into Peroxisome Matrix, Docking Protein Localization Establishment Of Localization In Cell Negative Regulation Of Protein Homooligomerization Protein Localization To Membrane Chaperone-mediated Protein Transport Protein To Membrane Docking Cellular Localization Negative Regulation Of Protein Oligomerization Peroxisome Fission Organelle Organization Membrane Biogenesis Very Long-chain Fatty Acid Metabolic Process Cerebral Cortex Neuron Differentiation Regulation Of Protein Oligomerization Membrane Organization Endoplasmic Reticulum Organization Fatty Acid Beta-oxidation Positive Regulation Of Multicellular Organism Growth Mitochondrial Membrane Organization Fatty Acid Oxidation Chaperone-mediated Protein Folding Lipid Oxidation Fatty Acid Catabolic Process Transport	Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Peroxisome Organization Intracellular Protein Transmembrane Transport Protein Transmembrane Transport Protein Import Into Peroxisome Matrix Protein Import Protein Import Into Peroxisome Membrane Peroxisomal Membrane Transport Establishment Of Protein Localization To Organelle Protein Targeting Protein Localization To Organelle Very Long-chain Fatty Acid Metabolic Process Cytoplasmic Transport Fatty Acid Beta-oxidation Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process Intracellular Protein Transport Negative Regulation Of Lipid Binding DNA Ligation Involved In DNA Recombination Positive Regulation Of SUMO Transferase Activity Organelle Organization Posttranscriptional Regulation Of Gene Expression Regulation Of Fibroblast Proliferation Negative Regulation Of Protein Homotetramerization Protein Import Into Peroxisome Matrix, Translocation Regulation Of Protein Stability Cellular Lipid Catabolic Process Peroxisome Membrane Biogenesis Protein Import Into Peroxisome Matrix, Docking Cellular Protein Localization Protein Transport Protein Targeting To Membrane Neuron Migration Establishment Of Protein Localization Lagging Strand Elongation Pro-B Cell Differentiation Negative Regulation Of Protein Homooligomerization Circadian Regulation Of Translation Intracellular Transport Lipid Modification Carboxylic Acid Catabolic Process Chaperone-mediated Protein Transport Protein To Membrane Docking Establishment Of Integrated Proviral Latency Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Immunoglobulin V(D)J Recombination Negative Regulation Of Protein Oligomerization
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