COQ3 and PTPN9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		COQ3	PTPN9
Description		coenzyme Q3, methyltransferase	protein tyrosine phosphatase non-receptor type 9
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Membrane Extrinsic Component Of Mitochondrial Inner Membrane Ubiquinone Biosynthesis Complex	Nucleoplasm Cytoplasm Neuron Projection Terminus
	Molecular Function	Protein Binding Methyltransferase Activity O-methyltransferase Activity Polyprenyldihydroxybenzoate Methyltransferase Activity Transferase Activity 3-demethylubiquinol 3-O-methyltransferase Activity 3-demethylubiquinone 3-O-methyltransferase Activity	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding Hydrolase Activity
	Biological Process	Glycerol Metabolic Process Ubiquinone Biosynthetic Process Methylation	Protein Dephosphorylation Signal Transduction Negative Regulation Of Neuron Projection Development Peptidyl-tyrosine Dephosphorylation Positive Regulation Of Protein Localization To Plasma Membrane
Pathways		Ubiquinol biosynthesis	Interleukin-37 signaling
Drugs
Diseases
GWAS		Regular attendance at a religious group ( 29970889)	Estimated glomerular filtration rate ( 31015462) Height ( 20189936 25429064 31562340 33713608) Hip circumference adjusted for BMI ( 34021172) Type 2 diabetes ( 30297969)
Interacting Genes		4 interacting genes: NDRG4 PTPN9 SNX1 TTPA	46 interacting genes: AGTRAP AQP6 ARL13B ARL6IP1 ATP5PF BSND CCR2 CDR1 CERS4 CMTM4 CMTM5 COQ3 CPLX4 CREB3 CREB3L1 DERL2 EBP FAM114A2 FKBP7 GET1 GHR GJB1 GORAB HSD17B11 HSD17B13 LIME1 LMNA MAL2 NSF PBX3 PEX12 PLIN3 REEP6 RTN3 SCAMP1 SLC16A13 SLC30A8 SLC7A1 SPAG4 STX6 SYP TMCO2 TMEM80 TMEM86B TMX2 YIF1A
Entrez ID		51805	5780
HPRD ID		07283	02864
Ensembl ID		ENSG00000132423	ENSG00000169410
Uniprot IDs		Q9NZJ6	P43378 Q6IQ43
PDB IDs			2PA5 4GE2 4GE5 4GE6 4ICZ 6KZQ 6L03
Enriched GO Terms of Interacting Partners?		Retromer, Tubulation Complex Leptin Receptor Binding Negative Regulation Of Establishment Of Blood-brain Barrier Regulation Of Establishment Of Blood-brain Barrier Vitamin E Binding Vitamin E Metabolic Process Non-membrane Spanning Protein Tyrosine Phosphatase Activity Regulation Of Cellular Localization Regulation Of Neuron Projection Development Neuron Projection Terminus Peptidyl-tyrosine Dephosphorylation Lipid Binding Transferrin Receptor Binding Early Endosome To Golgi Transport Lamellipodium Morphogenesis Retromer Complex Insulin Receptor Binding Phosphatidylinositol Bisphosphate Binding Lipid Transfer Activity Positive Regulation Of Amyloid-beta Clearance Regulation Of Amyloid-beta Clearance Regulation Of Endocytic Recycling Embryonic Heart Tube Development Cell Projection Membrane Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Cell Migration Involved In Heart Development Embryonic Placenta Development Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Steroid Dehydrogenase Activity Endoplasmic Reticulum Tubular Network Formation Protein Binding Endoplasmic Reticulum Tubular Network Membrane Organization Syntaxin Binding Non-motile Cilium Assembly
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