ZAK and VPS33B

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		ZAK	VPS33B
Gene Name		sterile alpha motif and leucine zipper containing kinase AZK	vacuolar protein sorting 33 homolog B (yeast)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm Lysosome Lysosomal Membrane Late Endosome HOPS Complex Platelet Alpha Granule Late Endosome Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding Poly(A) RNA Binding	Protein Binding
	Biological Process	Cell Cycle Checkpoint DNA Damage Checkpoint Activation Of MAPKK Activity Protein Phosphorylation Response To Stress Cytoskeleton Organization Cell Cycle Arrest Activation Of JUN Kinase Activity Cell Death Cell Proliferation Response To Radiation Cell Differentiation Intracellular Signal Transduction Positive Regulation Of Apoptotic Process	Vesicle Docking Involved In Exocytosis Protein Transport Vesicle-mediated Transport Melanosome Localization Lysosome Localization Membrane Fusion Platelet Alpha Granule Organization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: CCDC69 CRMP1 DDAH2 EZH2 IGHM ITSN1 MAP2K4 MAP2K6 MAP2K7 MIDN MPP1 NEDD4L RBX1 RNF19A RPS6KA5 SMARCB1 TGFBR1 UNC119 VPS33B YWHAG YWHAZ ZFP2 ZNF33A ZNF567 ZNF593 ZNF746 ZNF775	6 interactors: APP MAPK8IP2 TNIP1 UVRAG VIPAS39 ZAK
Entrez ID		51776	26276
HPRD ID		11791	10541
Ensembl ID		ENSG00000091436	ENSG00000184056
Uniprot IDs		D4Q8H0 Q9NYL2	B3KQF6 F5H008 Q9H267
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Sorbitol Positive Regulation Of Cell Death Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Regulation Of Phosphorylation Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Kinase Activity Regulation Of Phosphorus Metabolic Process Toll-like Receptor 4 Signaling Pathway Regulation Of Metabolic Process Positive Regulation Of Phosphorylation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Toll-like Receptor Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Kinase Activity Regulation Of Protein Kinase Activity Signal Transduction By Phosphorylation Regulation Of Caveolin-mediated Endocytosis Regulation Of Protein Phosphorylation Positive Regulation Of Kinase Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Regulation Of Cell Death Positive Regulation Of Transferase Activity Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Signal Transduction Positive Regulation Of Innate Immune Response Apoptotic Process Programmed Cell Death Positive Regulation Of MAP Kinase Activity Transcription, DNA-templated Positive Regulation Of Neuron Death Cellular Response To Carbohydrate Stimulus Positive Regulation Of Metabolic Process Intracellular Signal Transduction Cell Death	Mating Behavior Mating Positive Regulation Of Cellular Metabolic Process Regulation Of Phosphorylation JNK Cascade Regulation Of Phosphorus Metabolic Process Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Interaction With Host Regulation Of MAPK Cascade Positive Regulation Of Metabolic Process Response To Stress Stress-activated MAPK Cascade Regulation Of Receptor Activity Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Synaptic Growth At Neuromuscular Junction Learning Dendrite Development Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Sexual Reproduction Regulation Of JNK Cascade Collateral Sprouting In Absence Of Injury Regulation Of Stress-activated MAPK Cascade Regulation Of Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Nonassociative Learning MAPK Cascade Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Reproduction Regulation Of Protein Phosphorylation Axon Choice Point Recognition Learning Or Memory Positive Regulation Of Cellular Protein Metabolic Process Signal Transduction By Phosphorylation SNARE Complex Assembly Cognition Neuron Remodeling Regulation Of Signal Transduction Positive Regulation Of Protein Metabolic Process Cellular Protein Complex Assembly Reproductive Process Defense Response Regulation Of Signaling Signal Complex Assembly Cellular Response To Stress Positive Regulation Of Catalytic Activity Cellular Copper Ion Homeostasis
Tagcloud ?		adipogenic arresting associative ccpg1 chek chondrogenesis chondrogenic dedifferentiated dedifferentiation deriving dhcr24 dst g0s2 genechip hmga2 kat2 map2k6 maybe mll5 motivate msc osteogenesis prerequisites rassf4 rgs2 sesn3 transdifferentiate transdifferentiation unipotent	acidification associates atpase attributed coordinating depends dephosphorylation drives endosomal engulfment exclusion fusion luminal lysosome machinery macrophage macrophages maturation mtb multisubunit mycobacterial mycobacterium pathogenicity phagosome ptpa secreted sorting vacuolar
Tagcloud (Difference) ?		adipogenic arresting associative ccpg1 chek chondrogenesis chondrogenic dedifferentiated dedifferentiation deriving dhcr24 dst g0s2 genechip hmga2 kat2 map2k6 maybe mll5 motivate msc osteogenesis prerequisites rassf4 rgs2 sesn3 transdifferentiate transdifferentiation unipotent	acidification associates atpase attributed coordinating depends dephosphorylation drives endosomal engulfment exclusion fusion luminal lysosome machinery macrophage macrophages maturation mtb multisubunit mycobacterial mycobacterium pathogenicity phagosome ptpa secreted sorting vacuolar
Tagcloud (Intersection) ?