MAP3K20 and ZNF567

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		MAP3K20	ZNF567
Description		mitogen-activated protein kinase kinase kinase 20	zinc finger protein 567
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleus
	Molecular Function	Nucleotide Binding Magnesium Ion Binding RNA Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity JUN Kinase Kinase Kinase Activity MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity RRNA Binding Protein Kinase Regulator Activity Protein Kinase Activator Activity Ribosome Binding Metal Ion Binding Small Ribosomal Subunit RRNA Binding Protein Serine Kinase Activity Stalled Ribosome Sensor Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	DNA Damage Checkpoint Signaling MAPK Cascade Translational Initiation Protein Phosphorylation Inflammatory Response Cytoskeleton Organization Chromosome Segregation JNK Cascade Cell Death Regulation Of Mitotic Metaphase/anaphase Transition Cell Differentiation Stress-activated Protein Kinase Signaling Cascade Intracellular Signal Transduction P38MAPK Cascade Embryonic Digit Morphogenesis Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Protein Autophosphorylation Stress-activated MAPK Cascade Protein Maturation Limb Development Pyroptotic Inflammatory Response Negative Regulation Of Stress-activated Protein Kinase Signaling Cascade Cellular Response To Gamma Radiation Cellular Response To UV-B GCN2-mediated Signaling Negative Regulation Of Translation In Response To Endoplasmic Reticulum Stress Positive Regulation Of Mitotic DNA Damage Checkpoint NLRP1 Inflammasome Complex Assembly	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process
Pathways			Generic Transcription Pathway
Drugs		Dasatinib Fostamatinib
Diseases
GWAS		Haemorrhoidal disease ( 33888516)
Interacting Genes		29 interacting genes: CCDC69 CRMP1 DDAH2 EZH2 IGHM ITSN1 MAP2K4 MAP2K6 MAP2K7 MIDN MPP1 NEDD4L RBX1 RNF19A RPS6KA5 SMARCB1 SRPK2 TGFBR1 UNC119 VPS33B YWHAG YWHAZ ZFP2 ZNF33A ZNF567 ZNF593 ZNF660 ZNF746 ZNF775	3 interacting genes: FAM9B MAP3K20 PCBD1
Entrez ID		51776	163081
HPRD ID		11791	11728
Ensembl ID		ENSG00000091436	ENSG00000189042
Uniprot IDs		D4Q8H0 Q9NYL2	B2R956 B4E0D0 F8WEL6 Q8N184
PDB IDs		5HES 5X5O 6JUT 6JUU 7YAW 7YAZ
Enriched GO Terms of Interacting Partners?		Regulation Of Caveolin-mediated Endocytosis MAP Kinase Kinase Activity JUN Kinase Kinase Activity TORC1 Signaling Regulation Of Metabolic Process TOR Signaling Positive Regulation Of Caveolin-mediated Endocytosis Regulation Of Primary Metabolic Process MAPK Cascade Protein Serine/threonine Kinase Activity Protein Tyrosine Kinase Activity Regulation Of Synapse Organization Regulation Of RNA Metabolic Process Nucleus Protein Kinase Activity Cellular Senescence Protein Modification Process Regulation Of DNA-templated Transcription Regulation Of Macromolecule Metabolic Process Regulation Of RNA Biosynthetic Process Negative Regulation Of TORC1 Signaling Molecular Adaptor Activity Protein Serine Kinase Activity Regulation Of Motor Neuron Apoptotic Process Regulation Of Nucleobase-containing Compound Metabolic Process Transferase Activity Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Kinase Activity Intracellular Signal Transduction Negative Regulation Of TOR Signaling Regulation Of Macromolecule Biosynthetic Process Regulation Of TORC1 Signaling Stress-activated MAPK Cascade Fc-epsilon Receptor Signaling Pathway Stress-activated Protein Kinase Signaling Cascade P38MAPK Cascade Regulation Of Kinase Activity Spindle Midzone Blastocyst Development Hepatocyte Homeostasis Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Histone H2AS1 Kinase Activity Negative Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Regulation Of Postsynapse Organization Protein Metabolic Process	4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Tyrosine Biosynthetic Process Phenylalanine 4-monooxygenase Activity Tyrosine Biosynthetic Process, By Oxidation Of Phenylalanine Positive Regulation Of Mitotic DNA Damage Checkpoint Negative Regulation Of Translation In Response To Endoplasmic Reticulum Stress GCN2-mediated Signaling Stalled Ribosome Sensor Activity Positive Regulation Of DNA Damage Checkpoint Tetrahydrobiopterin Metabolic Process Tetrahydrobiopterin Biosynthetic Process JUN Kinase Kinase Kinase Activity Negative Regulation Of Translation In Response To Stress Small Ribosomal Subunit RRNA Binding NLRP1 Inflammasome Complex Assembly Regulation Of Translation In Response To Endoplasmic Reticulum Stress Negative Regulation Of Stress-activated Protein Kinase Signaling Cascade Pteridine-containing Compound Biosynthetic Process Cellular Response To UV-B Tyrosine Metabolic Process Protein Kinase Regulator Activity Positive Regulation Of Cell Cycle Checkpoint Response To UV-B Regulation Of DNA Damage Checkpoint Regulation Of Translation In Response To Stress MAP Kinase Kinase Kinase Activity Stress-activated Protein Kinase Signaling Cascade Stress-activated MAPK Cascade P38MAPK Cascade Synaptonemal Complex Diol Metabolic Process Cellular Response To Gamma Radiation Pteridine-containing Compound Metabolic Process Canonical Inflammasome Complex Assembly Aromatic Amino Acid Metabolic Process Regulation Of Stress-activated Protein Kinase Signaling Cascade Integrated Stress Response Signaling Pyroptotic Inflammatory Response Protein Kinase Activator Activity RRNA Binding Embryonic Digit Morphogenesis Response To Gamma Radiation Limb Development JNK Cascade Amino Acid Biosynthetic Process
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