ZAK and ZNF775

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		ZAK	ZNF775
Gene Name		sterile alpha motif and leucine zipper containing kinase AZK	zinc finger protein 775
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding Poly(A) RNA Binding	DNA Binding Metal Ion Binding
	Biological Process	Cell Cycle Checkpoint DNA Damage Checkpoint Activation Of MAPKK Activity Protein Phosphorylation Response To Stress Cytoskeleton Organization Cell Cycle Arrest Activation Of JUN Kinase Activity Cell Death Cell Proliferation Response To Radiation Cell Differentiation Intracellular Signal Transduction Positive Regulation Of Apoptotic Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: CCDC69 CRMP1 DDAH2 EZH2 IGHM ITSN1 MAP2K4 MAP2K6 MAP2K7 MIDN MPP1 NEDD4L RBX1 RNF19A RPS6KA5 SMARCB1 TGFBR1 UNC119 VPS33B YWHAG YWHAZ ZFP2 ZNF33A ZNF567 ZNF593 ZNF746 ZNF775	6 interactors: FES MAPK6 OSGEP PPP2CB RPS6KA5 ZAK
Entrez ID		51776	285971
HPRD ID		11791	14567
Ensembl ID		ENSG00000091436	ENSG00000196456
Uniprot IDs		D4Q8H0 Q9NYL2	Q96BV0
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Sorbitol Positive Regulation Of Cell Death Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Regulation Of Phosphorylation Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Kinase Activity Regulation Of Phosphorus Metabolic Process Toll-like Receptor 4 Signaling Pathway Regulation Of Metabolic Process Positive Regulation Of Phosphorylation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Toll-like Receptor Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Kinase Activity Regulation Of Protein Kinase Activity Signal Transduction By Phosphorylation Regulation Of Caveolin-mediated Endocytosis Regulation Of Protein Phosphorylation Positive Regulation Of Kinase Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Regulation Of Cell Death Positive Regulation Of Transferase Activity Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Signal Transduction Positive Regulation Of Innate Immune Response Apoptotic Process Programmed Cell Death Positive Regulation Of MAP Kinase Activity Transcription, DNA-templated Positive Regulation Of Neuron Death Cellular Response To Carbohydrate Stimulus Positive Regulation Of Metabolic Process Intracellular Signal Transduction Cell Death	MAPK Cascade Signal Transduction By Phosphorylation Protein Phosphorylation Phosphate-containing Compound Metabolic Process Cellular Protein Modification Process Histone H2A-S1 Phosphorylation Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Threonylcarbamoyladenosine Biosynthetic Process Phosphorylation Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Histone H3-S10 Phosphorylation Enzyme Linked Receptor Protein Signaling Pathway Cellular Protein Metabolic Process Positive Regulation Of Histone Phosphorylation Threonylcarbamoyladenosine Metabolic Process Histone H3-S28 Phosphorylation Signal Transduction Protein Metabolic Process Positive Regulation Of Microtubule Polymerization Signaling Positive Regulation Of Actin Cytoskeleton Reorganization Adenosine Metabolic Process Axon Guidance Cell Communication Positive Regulation Of Organelle Organization Cellular Response To Stress Interleukin-1-mediated Signaling Pathway Positive Regulation Of CREB Transcription Factor Activity Response To Stress Positive Regulation Of Histone Acetylation Histone-serine Phosphorylation Positive Regulation Of Peptidyl-lysine Acetylation Cellular Metabolic Process Positive Regulation Of Protein Acetylation Regulation Of Mast Cell Degranulation Axonogenesis Regulation Of Microtubule Polymerization Cellular Response To Stimulus Intracellular Signal Transduction Axon Development Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Response To Growth Factor Regulation Of Mast Cell Activation Peptidyl-tyrosine Autophosphorylation Activation Of JUN Kinase Activity
Tagcloud ?		adipogenic arresting associative ccpg1 chek chondrogenesis chondrogenic dedifferentiated dedifferentiation deriving dhcr24 dst g0s2 genechip hmga2 kat2 map2k6 maybe mll5 motivate msc osteogenesis prerequisites rassf4 rgs2 sesn3 transdifferentiate transdifferentiation unipotent
Tagcloud (Difference) ?		adipogenic arresting associative ccpg1 chek chondrogenesis chondrogenic dedifferentiated dedifferentiation deriving dhcr24 dst g0s2 genechip hmga2 kat2 map2k6 maybe mll5 motivate msc osteogenesis prerequisites rassf4 rgs2 sesn3 transdifferentiate transdifferentiation unipotent
Tagcloud (Intersection) ?