ZAK and RNF19A

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		ZAK	RNF19A
Gene Name		sterile alpha motif and leucine zipper containing kinase AZK	ring finger protein 19A, RBR E3 ubiquitin protein ligase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Cytoplasm Centrosome Integral Component Of Membrane
	Molecular Function	Magnesium Ion Binding Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding Poly(A) RNA Binding	Transcription Factor Binding Zinc Ion Binding Ligase Activity
	Biological Process	Cell Cycle Checkpoint DNA Damage Checkpoint Activation Of MAPKK Activity Protein Phosphorylation Response To Stress Cytoskeleton Organization Cell Cycle Arrest Activation Of JUN Kinase Activity Cell Death Cell Proliferation Response To Radiation Cell Differentiation Intracellular Signal Transduction Positive Regulation Of Apoptotic Process	Microtubule Cytoskeleton Organization Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS			Atrioventricular conduction ( 21041692)
Protein-Protein Interactions		27 interactors: CCDC69 CRMP1 DDAH2 EZH2 IGHM ITSN1 MAP2K4 MAP2K6 MAP2K7 MIDN MPP1 NEDD4L RBX1 RNF19A RPS6KA5 SMARCB1 TGFBR1 UNC119 VPS33B YWHAG YWHAZ ZFP2 ZNF33A ZNF567 ZNF593 ZNF746 ZNF775	16 interactors: C11orf58 CASR ILK MAP3K7 NUDT21 RPS6KA5 SNCAIP SOD1 SUFU TUBG1 TUBG2 UBE2E2 UBE2L3 UBE2L6 VCP ZAK
Entrez ID		51776	25897
HPRD ID		11791	06176
Ensembl ID		ENSG00000091436	ENSG00000034677
Uniprot IDs		D4Q8H0 Q9NYL2	Q9NV58
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Sorbitol Positive Regulation Of Cell Death Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Regulation Of Phosphorylation Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Kinase Activity Regulation Of Phosphorus Metabolic Process Toll-like Receptor 4 Signaling Pathway Regulation Of Metabolic Process Positive Regulation Of Phosphorylation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Toll-like Receptor Signaling Pathway Regulation Of Nitrogen Compound Metabolic Process Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Protein Phosphorylation Positive Regulation Of Protein Kinase Activity Regulation Of Protein Kinase Activity Signal Transduction By Phosphorylation Regulation Of Caveolin-mediated Endocytosis Regulation Of Protein Phosphorylation Positive Regulation Of Kinase Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Regulation Of Cell Death Positive Regulation Of Transferase Activity Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Signal Transduction Positive Regulation Of Innate Immune Response Apoptotic Process Programmed Cell Death Positive Regulation Of MAP Kinase Activity Transcription, DNA-templated Positive Regulation Of Neuron Death Cellular Response To Carbohydrate Stimulus Positive Regulation Of Metabolic Process Intracellular Signal Transduction Cell Death	Positive Regulation Of Protein Modification Process Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Cellular Protein Metabolic Process ISG15-protein Conjugation Positive Regulation Of Protein Metabolic Process Positive Regulation Of MAP Kinase Activity MAPK Cascade Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Transferase Activity JNK Cascade Cellular Response To Stress Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Catalytic Activity Signal Transduction By Phosphorylation Regulation Of Protein Metabolic Process Regulation Of MAP Kinase Activity Positive Regulation Of Protein Phosphorylation Microtubule Nucleation Epithelial Tube Morphogenesis Protein K11-linked Ubiquitination Cellular Response To Organic Substance Activation Of MAPK Activity Response To Stress Microtubule Polymerization Tube Morphogenesis Positive Regulation Of MAPK Cascade Positive Regulation Of Phosphorylation Positive Regulation Of Protein Kinase Activity Vasodilation Positive Regulation Of Kinase Activity Cytoplasmic Microtubule Organization Morphogenesis Of An Epithelium Microtubule Polymerization Or Depolymerization Regulation Of Cytokine Production Protein Complex Assembly Cell Cycle Process Myelination In Peripheral Nervous System Regulation Of Catalytic Activity Protein Ubiquitination Cellular Protein Modification Process Regulation Of Protein Phosphorylation Schwann Cell Development Epithelium Development Toll-like Receptor 5 Signaling Pathway Protein Modification By Small Protein Conjugation Toll-like Receptor 10 Signaling Pathway Regulation Of MAPK Cascade Cell Cycle Phase Transition Response To Organic Substance
Tagcloud ?		adipogenic arresting associative ccpg1 chek chondrogenesis chondrogenic dedifferentiated dedifferentiation deriving dhcr24 dst g0s2 genechip hmga2 kat2 map2k6 maybe mll5 motivate msc osteogenesis prerequisites rassf4 rgs2 sesn3 transdifferentiate transdifferentiation unipotent
Tagcloud (Difference) ?		adipogenic arresting associative ccpg1 chek chondrogenesis chondrogenic dedifferentiated dedifferentiation deriving dhcr24 dst g0s2 genechip hmga2 kat2 map2k6 maybe mll5 motivate msc osteogenesis prerequisites rassf4 rgs2 sesn3 transdifferentiate transdifferentiation unipotent
Tagcloud (Intersection) ?