ZNF44 and FBXL12

		ZNF44	FBXL12
Description		zinc finger protein 44	F-box and leucine rich repeat protein 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Ubiquitin Ligase Complex Cytoplasm Cytosol
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Zinc Ion Binding Metal Ion Binding	Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination
Pathways			Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Pursuit maintenance gain ( 29064472)
Interacting Genes		4 interacting genes: CSNK2B HGS TLX3 UPF2	19 interacting genes: A2M ALDH3A1 APOE CDC37 CDKN1C DOCK8 ECSIT FBF1 FXYD3 GEMIN4 LNX1 MAST1 PSEN1 PSEN2 PSME3 RNF32 SMAD1 TGFBR1 UBE2D3
Entrez ID		51710	54850
HPRD ID		01927	12363
Ensembl ID		ENSG00000197857	ENSG00000127452
Uniprot IDs		F8W7T7 P15621	Q9NXK8
PDB IDs
Enriched GO Terms of Interacting Partners?			Amyloid Precursor Protein Metabolic Process Positive Regulation Of Amyloid Fibril Formation Aspartic Endopeptidase Activity, Intramembrane Cleaving Gamma-secretase Complex Notch Receptor Processing Amyloid-beta Formation Regulation Of Amyloid Fibril Formation I-SMAD Binding Amyloid Precursor Protein Catabolic Process
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