VPS29 and RGS2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		VPS29	RGS2
Description		VPS29 retromer complex component	regulator of G protein signaling 2
Image
GO Annotations	Cellular Component	Cytoplasm Endosome Early Endosome Late Endosome Cytosol Endosome Membrane Membrane Retromer Complex Retromer, Cargo-selective Complex	Nucleus Nucleolus Cytoplasm Mitochondrion Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane
	Molecular Function	Protein Binding Metal Ion Binding	G-protein Alpha-subunit Binding GTPase Activity GTPase Activator Activity Protein Binding Calmodulin Binding Adenylate Cyclase Inhibitor Activity Beta-tubulin Binding
	Biological Process	Intracellular Protein Transport Regulation Of Autophagy Protein Transport Endocytic Recycling Retrograde Transport, Endosome To Golgi	Response To Amphetamine Regulation Of Translation G Protein-coupled Receptor Signaling Pathway Spermatogenesis Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Negative Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Neuron Projection Development Negative Regulation Of Translation Response To Ethanol Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of JNK Cascade Brown Fat Cell Differentiation Relaxation Of Cardiac Muscle Relaxation Of Vascular Associated Smooth Muscle Maternal Process Involved In Female Pregnancy Positive Regulation Of Cardiac Muscle Contraction Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of Adenylate Cyclase-inhibiting Adrenergic Receptor Signaling Pathway Positive Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Glycine Import Across Plasma Membrane
Pathways		WNT ligand biogenesis and trafficking	G alpha (q) signalling events
Drugs
Diseases
GWAS			Coronary artery calcification ( 23870195) Response to quetiapine in schizophrenia ( 29503163)
Interacting Genes		6 interacting genes: APP FRA10AC1 RGS2 SNCA TMCO4 VPS35	61 interacting genes: ADCY5 ADRA1A ADRB2 ARFGAP1 BBS10 CALM1 CEP126 CHD3 CIAO1 CLTA COMT COPB1 COPB2 CRMP1 CTSB DDR1 DUSP21 DYNLL1 EGFR EIF3L FZD5 GDE1 GIT1 GNA15 GNAI3 GNAQ GNAS HAUS5 HSPA8 IER3IP1 KLK8 LIG1 LRFN1 MARCHF6 METTL18 MON1A MTUS2 NINL NIPSNAP1 PPP1R9B PRKCA PRKCB PRKCG PRKCSH PRKG1 PRKN RAB2A RABAC1 RAP1B REEP5 RIN3 SCN5A TSPAN15 TUBB2B UBC VPS29 WDR74 XRCC6 ZBTB48 ZNF579 ZYX
Entrez ID		51699	5997
HPRD ID		09499	02917
Ensembl ID		ENSG00000111237	ENSG00000116741
Uniprot IDs		A0A384MR19 F8VXU5 Q9UBQ0	P41220
PDB IDs		1W24 2R17 5GTU 5OSH 5OSI 5WYH 6XS5 6XS7 6XS9 6XSA 7BLN 8ESE 8P0V 8P0X 8R02 8R0J 8RKS 8SYM 8SYN 8SYO 9AU7	2AF0 2V4Z 4EKC 4EKD
Enriched GO Terms of Interacting Partners?		Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Presynapse Organization Regulation Of Presynapse Assembly Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Dendritic Spine Maintenance Regulation Of Synapse Assembly Regulation Of Neurotransmitter Uptake Regulation Of Dopamine Metabolic Process Cellular Response To Copper Ion Regulation Of Long-term Neuronal Synaptic Plasticity Amyloid Fibril Formation Microglial Cell Activation Presynapse Response To Copper Ion Postsynapse Leukocyte Activation Involved In Inflammatory Response Regulation Of Cell Junction Assembly Beta-tubulin Binding Regulation Of Synapse Organization Regulation Of Neuronal Synaptic Plasticity Protein Destabilization Amyloid-beta Complex Growth Cone Lamellipodium Myeloid Cell Development Regulation Of Response To Calcium Ion Macrophage Activation Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Protein Catabolic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Adenylate Cyclase-inhibiting Adrenergic Receptor Signaling Pathway Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of Terminal Button Organization Regulation Of Amine Transport Positive Regulation Of Protein Localization To Cell Periphery Adult Locomotory Behavior Regulation Of Inflammatory Response Response To Interleukin-1 Negative Regulation Of Transport Positive Regulation Of Cellular Component Organization Positive Regulation Of Protein Localization Protein Tetramerization Vesicle-mediated Transport In Synapse Acetylcholine Receptor Activator Activity Modulation Of Chemical Synaptic Transmission	Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Guanyl Nucleotide Binding Calyx Of Held G-protein Beta/gamma-subunit Complex Binding Cognition Nucleotide Binding Regulation Of Secretion By Cell Scaffold Protein Binding Protein-containing Complex Binding Learning Or Memory Heterotrimeric G-protein Complex G Protein-coupled Receptor Binding Regulation Of Transport Response To Ketone Regulation Of Secretion Enzyme Binding Histone H3T6 Kinase Activity Regulation Of Neurotransmitter Secretion Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Response To Corticosterone Diacylglycerol-dependent Serine/threonine Kinase Activity Regulation Of Synaptic Vesicle Exocytosis Regulation Of Insulin Secretion Regulation Of Muscle System Process Regulation Of Muscle Contraction Response To Alcohol Regulation Of Protein Secretion System Process Response To Catecholamine Cytoplasm Nervous System Process Adrenergic Receptor Signaling Pathway Modulation Of Chemical Synaptic Transmission G Protein-coupled Acetylcholine Receptor Signaling Pathway Regulation Of Exocytosis Response To Hormone Cellular Localization Protein Kinase C Signaling Membrane Regulation Of Peptide Hormone Secretion Establishment Of Localization In Cell Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Cellular Component Organization G Protein-coupled Receptor Signaling Pathway Centrosome Regulation Of Establishment Of Protein Localization Response To Psychosocial Stress Adenylate Cyclase Activator Activity Intracellular Protein Localization G Protein Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?