MPC1 and GABARAP

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		MPC1	GABARAP
Gene Name		mitochondrial pyruvate carrier 1	GABA(A) receptor-associated protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Mitochondrion Mitochondrial Inner Membrane Integral Component Of Membrane	Golgi Membrane Pre-autophagosomal Structure Autophagic Vacuole Membrane Lysosome Autophagic Vacuole Smooth Endoplasmic Reticulum Cytosol Microtubule Microtubule Associated Complex Plasma Membrane Axoneme Actin Cytoskeleton Extrinsic Component Of Membrane Cytoplasmic Vesicle Cell Body Perinuclear Region Of Cytoplasm
	Molecular Function	Molecular_function Pyruvate Transmembrane Transporter Activity	Protein Binding Microtubule Binding Beta-tubulin Binding GABA Receptor Binding
	Biological Process	Pyruvate Metabolic Process Mitochondrial Pyruvate Transport Biological_process Cellular Metabolic Process Small Molecule Metabolic Process Pyruvate Transmembrane Transport	Autophagic Vacuole Assembly Microtubule Cytoskeleton Organization Mitochondrion Degradation Protein Targeting Synaptic Transmission Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Nucleophagy Membrane Fusion
Pathways		Pyruvate metabolism Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: ACTC1 GABARAP MAGED1	29 interactors: AES ATG101 ATG13 ATG3 ATG4B ATG7 DMPK DVL2 GABRG1 GABRG2 GABRG3 GPHN HDAC5 MAPK15 MLH1 MPC1 NSF PGS1 PKP4 RB1CC1 SRPK1 SRPK2 TAX1BP1 TBC1D25 TFRC TUBB3 ULK1 ULK2 VPS28
Entrez ID		51660	11337
HPRD ID		07091	05496
Ensembl ID		ENSG00000060762
Uniprot IDs		Q5TI65 Q9Y5U8	O95166 Q6IAW1
PDB IDs			1GNU 1KLV 1KM7 1KOT 3D32 3DOW
Enriched GO Terms of Interacting Partners?		Apoptotic Process Programmed Cell Death Cell Death Death Apoptotic Signaling Pathway Skeletal Muscle Thin Filament Assembly Skeletal Myofibril Assembly Organelle Assembly Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Regulation Of Branching Involved In Ureteric Bud Morphogenesis Nucleophagy Cardiac Myofibril Assembly Mitochondrion Degradation Muscle Filament Sliding Actin-myosin Filament Sliding	Autophagic Vacuole Assembly Autophagy Macroautophagy Cellular Response To Extracellular Stimulus Cellular Response To Starvation Response To Starvation Cellular Response To Nutrient Levels Vacuole Organization Response To Extracellular Stimulus Response To Nutrient Levels Organelle Assembly Regulation Of Autophagy Cell Communication Cellular Component Assembly Nucleophagy Catabolic Process Organelle Organization Mitochondrion Degradation Gamma-aminobutyric Acid Signaling Pathway Positive Regulation Of Autophagy Organelle Disassembly Cellular Response To Stimulus Negative Regulation Of Collateral Sprouting Response To Stimulus Response To External Stimulus Cellular Response To Stress Membrane Organization Response To Stress Positive Regulation Of Macroautophagy Cellular Process Cellular Response To Nitrogen Starvation Cellular Metabolic Process Protein Localization Positive Regulation Of Viral Genome Replication Chloride Transmembrane Transport Nucleus Organization C-terminal Protein Lipidation Chloride Transport Regulation Of Cell Size Regulation Of Metabolic Process Cellular Protein Metabolic Process Cellular Protein Modification Process Signaling Protein Localization To Membrane Axon Extension Positive Regulation Of Metabolic Process Anion Transmembrane Transport Glycine Receptor Clustering Nuclear Speck Organization Regulation Of Autophagic Vacuole Maturation
Tagcloud ?		1q12 bmi1 concentrates deacetylation eed ezh2 heritable heterochromatin hmtase homologs hpc hpc2 hph k9 m33 methyltransferase multimeric observe pcg pericentromeric polycomb relocalization repress repression ring1 suv39h1 utilizes vertebrate xpc2	akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional henceforth lc3b map1lc3b olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask
Tagcloud (Difference) ?		1q12 bmi1 concentrates deacetylation eed ezh2 heritable heterochromatin hmtase homologs hpc hpc2 hph k9 m33 methyltransferase multimeric observe pcg pericentromeric polycomb relocalization repress repression ring1 suv39h1 utilizes vertebrate xpc2	akt1 antipsychotic atg atg12 atg4b atg5 atg7 autophagic autophagosome autophagosomes autophagy bak1 bcl2l11 becn1 cdkn1a cdkn1b chloroquine colocalization dysfunctional henceforth lc3b map1lc3b olanzapine overtly pmaip1 sqstm1 sy5y trp53 unmask
Tagcloud (Intersection) ?