ATP6V1H and ETHE1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		ATP6V1H	ETHE1
Gene Name		ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H	ethylmalonic encephalopathy 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Vacuolar Proton-transporting V-type ATPase, V1 Domain Lysosomal Membrane Cytosol Plasma Membrane Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	Protein Binding ATPase Activity Enzyme Regulator Activity Proton-transporting ATPase Activity, Rotational Mechanism	Iron Ion Binding Sulfur Dioxygenase Activity
	Biological Process	Cellular Iron Ion Homeostasis Endocytosis Vacuolar Acidification Metabolic Process Insulin Receptor Signaling Pathway ATP Hydrolysis Coupled Proton Transport Viral Process Transferrin Transport Regulation Of Defense Response To Virus By Virus Regulation Of Catalytic Activity Interaction With Host Transmembrane Transport Phagosome Maturation	Sulfur Amino Acid Metabolic Process Sulfur Amino Acid Catabolic Process Glutathione Metabolic Process Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process Sulfide Oxidation, Using Sulfide:quinone Oxidoreductase Hydrogen Sulfide Metabolic Process
Pathways		Phagosomal maturation (early endosomal stage) Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters Iron uptake and transport HIV Infection Nef Mediated CD8 Down-regulation Host Interactions of HIV factors The role of Nef in HIV-1 replication and disease pathogenesis Transferrin endocytosis and recycling Insulin receptor recycling Latent infection of Homo sapiens with Mycobacterium tuberculosis Nef Mediated CD4 Down-regulation Signaling by Insulin receptor	Sulfide oxidation to sulfate Degradation of cysteine and homocysteine Sulfur amino acid metabolism Metabolism of amino acids and derivatives
Drugs
Diseases
GWAS		Bipolar disorder (mood-incongruent) ( 23092984)
Protein-Protein Interactions		4 interactors: ATP6V1E1 ETHE1 SOX9 TANK	5 interactors: APP ATP6V1H IGSF21 LRIF1 RELA
Entrez ID		51606	23474
HPRD ID		10591	09764
Ensembl ID		ENSG00000047249	ENSG00000105755
Uniprot IDs		B3KUZ7 B4E054 G3V126 Q9UI12	B2RCZ7 M0QXB5 O95571
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Proliferation Involved In Tissue Homeostasis Epithelial Cell Proliferation Involved In Prostatic Bud Elongation Retinal Rod Cell Differentiation Primary Prostatic Bud Elongation Male Germ-line Sex Determination Renal Vesicle Induction Primary Sex Determination Astrocyte Fate Commitment Positive Regulation Of Extracellular Matrix Assembly Metanephric Nephron Tubule Formation Intestinal Epithelial Structure Maintenance Intrahepatic Bile Duct Development Positive Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Photoreceptor Cell Differentiation Cellular Response To Heparin Sulfide Oxidation, Using Sulfide:quinone Oxidoreductase Regulation Of Extracellular Matrix Assembly Ureter Urothelium Development Hydrogen Sulfide Metabolic Process Response To Heparin Ureter Morphogenesis Ureter Smooth Muscle Cell Differentiation Chondrocyte Hypertrophy Metanephric Tubule Formation Regulation Of Mesenchymal Stem Cell Differentiation Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Common Bile Duct Development Metanephric Nephron Tubule Morphogenesis Limb Bud Formation Otic Vesicle Formation Positive Regulation Of Male Gonad Development Otic Vesicle Morphogenesis Regulation Of Branching Involved In Lung Morphogenesis Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis Negative Regulation Of Mesenchymal Cell Apoptotic Process Metanephric Tubule Morphogenesis Cellular Response To Organonitrogen Compound Camera-type Eye Photoreceptor Cell Differentiation Sulfur Amino Acid Catabolic Process Male Sex Determination Maintenance Of Gastrointestinal Epithelium Otic Vesicle Development Ureter Development ERK1 And ERK2 Cascade Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Heart Valve Formation Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis Metanephric Nephron Tubule Development Nephron Tubule Formation Epithelial Structure Maintenance	Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Acetaldehyde Metabolic Process Transition Metal Ion Homeostasis Positive Regulation Of Schwann Cell Differentiation Synaptic Growth At Neuromuscular Junction Intracellular Receptor Signaling Pathway Collateral Sprouting In Absence Of Injury Regulation Of Schwann Cell Differentiation Response To Cobalamin Collateral Sprouting Axon Midline Choice Point Recognition Response To Insulin Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of MiRNA Metabolic Process Cellular Response To Peptide Hormone Stimulus Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Axon Choice Point Recognition Cellular Response To Peptide Response To Light Stimulus Cellular Response To Nicotine Positive Regulation Of Interleukin-12 Biosynthetic Process Neuron Remodeling Cellular Metal Ion Homeostasis Regulation Of MiRNA Metabolic Process Response To Oxidative Stress Vacuolar Acidification Cellular Cation Homeostasis Response To Radiation Response To Peptide Hormone Cellular Ion Homeostasis Regulation Of Interleukin-12 Biosynthetic Process Cellular Response To Organonitrogen Compound Metal Ion Homeostasis Response To Peptide Response To Muramyl Dipeptide Response To UV-B Membrane Protein Intracellular Domain Proteolysis Cellular Chemical Homeostasis Cellular Copper Ion Homeostasis Viral Process Ion Homeostasis Intracellular PH Reduction Cellular Response To Hormone Stimulus PH Reduction Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Defense Response To Virus By Virus Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Cellular Response To Interleukin-6
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?