ATP6V1H and SNPH

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ATP6V1H	SNPH
Description		ATPase H+ transporting V1 subunit H	syntaphilin
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Vacuolar Proton-transporting V-type ATPase, V1 Domain Lysosomal Membrane Cytosol Plasma Membrane Endosome Membrane Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Proton-transporting V-type ATPase Complex Extracellular Exosome Extrinsic Component Of Synaptic Vesicle Membrane	Cytoplasm Mitochondrion Cytoplasmic Microtubule Membrane Neuron Projection Synapse Presynapse
	Molecular Function	Protein Binding ATP Hydrolysis Activity Enzyme Regulator Activity Proton-transporting ATPase Activity, Rotational Mechanism	Protein Binding Syntaxin-1 Binding
	Biological Process	Monoatomic Ion Transport Endocytosis Vacuolar Acidification Lysosomal Lumen Acidification Regulation Of Macroautophagy Endosomal Lumen Acidification Intracellular PH Reduction Golgi Lumen Acidification Proton Transmembrane Transport	Neurotransmitter Secretion Synaptic Vesicle Docking Neuron Differentiation
Pathways		ROS and RNS production in phagocytes Nef Mediated CD4 Down-regulation Nef Mediated CD8 Down-regulation Insulin receptor recycling Transferrin endocytosis and recycling Blockage of phagosome acidification Amino acids regulate mTORC1 Ion channel transport Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy
Drugs		Tiludronic acid
Diseases
GWAS		Bipolar disorder with mood-incongruent psychosis ( 23092984) Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814)	Body mass index ( 28552196) Lean body mass ( 28552196) Response to cytadine analogues (cytosine arabinoside) ( 24483146)
Interacting Genes		10 interacting genes: ATP6V1E1 CDKN2B ETHE1 FLACC1 PPP1R12C SNPH SOX9 SPATA2 TANK TRIM14	6 interacting genes: ATP6V1H PRKACA RHBDD2 STUB1 STX1A XPA
Entrez ID		51606	9751
HPRD ID		10591	16081
Ensembl ID		ENSG00000047249	ENSG00000101298
Uniprot IDs		B3KUZ7 Q9UI12	A0A3B3IRY9 O15079
PDB IDs		6WM2 6WM3 6WM4 7FDA 7FDB 7FDC 7U4T 7UNF
Enriched GO Terms of Interacting Partners?		Proton-transporting Two-sector ATPase Complex, Catalytic Domain Response To Interleukin-1 Neural Crest Cell Fate Specification Male Germ-line Sex Determination Cellular Response To Interleukin-1 Negative Regulation Of Beta-catenin-TCF Complex Assembly Bronchus Cartilage Development Ureter Urothelium Development Epithelial Cell Proliferation Involved In Prostatic Bud Elongation Regulation Of Cell Proliferation Involved In Tissue Homeostasis Ureter Smooth Muscle Cell Differentiation Lung Smooth Muscle Development Intrahepatic Bile Duct Development Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Ubiquitin-specific Protease Activity Sulfur Dioxygenase Activity Cytoplasm Proton-transporting Two-sector ATPase Complex Negative Regulation Of Epithelial Cell Proliferation Cellular Response To Cell-matrix Adhesion Negative Regulation Of Photoreceptor Cell Differentiation Metanephric Tubule Formation Stem Cell Fate Specification Renal Vesicle Induction Metanephric Nephron Tubule Formation Positive Regulation Of Mesenchymal Stem Cell Differentiation Chondrocyte Hypertrophy Cell Proliferation Involved In Heart Morphogenesis Trachea Cartilage Development Response To Heparin Prostate Gland Morphogenesis Cellular Response To Heparin Regulation Of Branching Involved In Lung Morphogenesis Endochondral Bone Morphogenesis Anterior Head Development Primary Sex Determination Harderian Gland Development Astrocyte Fate Commitment Common Bile Duct Development Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis Growth Plate Cartilage Chondrocyte Growth Lacrimal Gland Development Protein Linear Deubiquitination Protein Deubiquitination Protein Modification By Small Protein Removal Positive Regulation Of Protein Deubiquitination Hydrogen Sulfide Metabolic Process Myosin Phosphatase Regulator Activity Phosphatase Regulator Activity Ureter Development	Regulation Of Autophagy Regulation Of Macroautophagy Cellular Response To Heat Response To Heat Proteasomal Protein Catabolic Process Myosin Head/neck Binding Nucleotide-excision Repair, DNA Damage Recognition Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Chaperone-mediated Protein Complex Assembly ERAD Pathway Regulation Of Hormone Levels Regulation Of Steroid Metabolic Process Kinase Binding Regulation Of System Process Nucleotide-excision Repair Involved In Interstrand Cross-link Repair Cellular Response To Stress Intracellular Signal Transduction Response To Temperature Stimulus Regulation Of Insulin Secretion Negative Regulation Of Glycolytic Process Through Fructose-6-phosphate Proteolysis Involved In Protein Catabolic Process Protein Localization To Lipid Droplet Regulation Of Muscle Contraction Protein Catabolic Process Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Positive Regulation Of Norepinephrine Secretion Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Nucleotide-excision Repair Factor 1 Complex Negative Regulation Of Vascular Associated Smooth Muscle Contraction Ubiquitin Conjugating Enzyme Complex CAMP-dependent Protein Kinase Complex Regulation Of Hormone Secretion Regulation Of Peptide Hormone Secretion Cellular Response To Parathyroid Hormone Stimulus Regulation Of Proteasomal Protein Catabolic Process Cellular Response To Glucagon Stimulus Regulation Of Blood Circulation Protein Domain Specific Binding CAMP-dependent Protein Kinase Activity Interleukin-2-mediated Signaling Pathway Regulation Of Muscle System Process Cellular Response To Epinephrine Stimulus High-density Lipoprotein Particle Assembly Cytoplasmic Vesicle Macromolecule Catabolic Process Mitochondrial Protein Catabolic Process Regulation Of Protein Secretion CAMP/PKA Signal Transduction Nucleotide-activated Protein Kinase Complex
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