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ATP6V1H and SOX9
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
ATP6V1H
SOX9
Gene Name
ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
SRY (sex determining region Y)-box 9
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Vacuolar Proton-transporting V-type ATPase, V1 Domain
Lysosomal Membrane
Cytosol
Plasma Membrane
Extracellular Vesicular Exosome
Nucleus
Nucleoplasm
Protein Complex
Nuclear Transcription Factor Complex
Molecular Function
Protein Binding
ATPase Activity
Enzyme Regulator Activity
Proton-transporting ATPase Activity, Rotational Mechanism
Core Promoter Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
Enhancer Sequence-specific DNA Binding
Chromatin Binding
Sequence-specific DNA Binding Transcription Factor Activity
RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity
Protein Kinase Activity
Protein Binding
Beta-catenin Binding
Protein Kinase A Catalytic Subunit Binding
Enhancer Binding
BHLH Transcription Factor Binding
Protein Heterodimerization Activity
Pre-mRNA Intronic Binding
Biological Process
Cellular Iron Ion Homeostasis
Endocytosis
Vacuolar Acidification
Metabolic Process
Insulin Receptor Signaling Pathway
ATP Hydrolysis Coupled Proton Transport
Viral Process
Transferrin Transport
Regulation Of Defense Response To Virus By Virus
Regulation Of Catalytic Activity
Interaction With Host
Transmembrane Transport
Phagosome Maturation
Skeletal System Development
Cartilage Condensation
Ossification
Branching Involved In Ureteric Bud Morphogenesis
Cell Fate Specification
Epithelial To Mesenchymal Transition
Tissue Homeostasis
Positive Regulation Of Protein Phosphorylation
Hair Follicle Development
Positive Regulation Of Mesenchymal Cell Proliferation
Negative Regulation Of Immune System Process
Heart Valve Development
Heart Valve Morphogenesis
Heart Valve Formation
Endocardial Cushion Morphogenesis
Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis
Chondrocyte Hypertrophy
Nucleosome Assembly
Chromatin Remodeling
Transcription From RNA Polymerase II Promoter
Protein Complex Assembly
Protein Phosphorylation
Cytoskeleton Organization
Signal Transduction
Epidermal Growth Factor Receptor Signaling Pathway
Spermatogenesis
Positive Regulation Of Cell Proliferation
Male Gonad Development
Regulation Of Cell Cycle Process
Positive Regulation Of Epithelial Cell Migration
Neural Crest Cell Development
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Single Organismal Cell-cell Adhesion
Male Germ-line Sex Determination
CAMP-mediated Signaling
Regulation Of Cell Adhesion
Extracellular Matrix Organization
Negative Regulation Of Ossification
Negative Regulation Of Bone Mineralization
Prostate Gland Development
Negative Regulation Of Epithelial Cell Differentiation
Positive Regulation Of Epithelial Cell Differentiation
Mammary Gland Development
Notochord Development
Otic Vesicle Formation
Endocrine Pancreas Development
Negative Regulation Of Chondrocyte Differentiation
Positive Regulation Of Chondrocyte Differentiation
Somatic Stem Cell Maintenance
Intrahepatic Bile Duct Development
Regulation Of Cell Proliferation
Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Protein Kinase B Signaling
Negative Regulation Of Myoblast Differentiation
Positive Regulation Of Protein Catabolic Process
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Photoreceptor Cell Differentiation
Oligodendrocyte Differentiation
Positive Regulation Of Epithelial Cell Proliferation
Negative Regulation Of Epithelial Cell Proliferation
Cartilage Development
Sertoli Cell Differentiation
Sertoli Cell Development
Astrocyte Fate Commitment
Retina Development In Camera-type Eye
Limb Bud Formation
Retinal Rod Cell Differentiation
Epithelial Tube Branching Involved In Lung Morphogenesis
Lung Epithelial Cell Differentiation
Epithelial Cell Proliferation Involved In Prostatic Bud Elongation
Intestinal Epithelial Structure Maintenance
Regulation Of Cell Proliferation Involved In Tissue Homeostasis
Positive Regulation Of Cartilage Development
Regulation Of Branching Involved In Lung Morphogenesis
Morphogenesis Of A Branching Epithelium
Negative Regulation Of Biomineral Tissue Development
ERK1 And ERK2 Cascade
Cellular Response To Mechanical Stimulus
Cellular Response To Retinoic Acid
Cellular Response To Interleukin-1
Cellular Response To Epidermal Growth Factor Stimulus
Cellular Response To Heparin
Cellular Response To Transforming Growth Factor Beta Stimulus
Renal Vesicle Induction
Ureter Urothelium Development
Ureter Smooth Muscle Cell Differentiation
Ureter Morphogenesis
Metanephric Nephron Tubule Formation
Negative Regulation Of Canonical Wnt Signaling Pathway
Cochlea Morphogenesis
Positive Regulation Of Kidney Development
Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis
Positive Regulation Of Extracellular Matrix Assembly
Positive Regulation Of Male Gonad Development
Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis
Positive Regulation Of Mesenchymal Stem Cell Differentiation
Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis
Negative Regulation Of Mesenchymal Cell Apoptotic Process
Pathways
Phagosomal maturation (early endosomal stage)
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
Iron uptake and transport
HIV Infection
Nef Mediated CD8 Down-regulation
Host Interactions of HIV factors
The role of Nef in HIV-1 replication and disease pathogenesis
Transferrin endocytosis and recycling
Insulin receptor recycling
Latent infection of Homo sapiens with Mycobacterium tuberculosis
Nef Mediated CD4 Down-regulation
Signaling by Insulin receptor
Drugs
Diseases
GWAS
Bipolar disorder (mood-incongruent) (
23092984
)
Bone mineral density (
22504420
)
Liver enzyme levels (gamma-glutamyl transferase) (
22001757
)
Pulmonary function (interaction) (
23284291
)
Pulmonary function decline (
22424883
)
Thyroid hormone levels (
23408906
)
Protein-Protein Interactions
4 interactors:
ATP6V1E1
ETHE1
SOX9
TANK
14 interactors:
ATP6V1H
CREB1
CREB3L4
CREBBP
EP300
HERC1
HSPA1A
KPNB1
MAF
MED12
NR5A1
RUNX2
SPEN
TRAF2
Entrez ID
51606
6662
HPRD ID
10591
06427
Ensembl ID
ENSG00000047249
ENSG00000125398
Uniprot IDs
B3KUZ7
B4E054
G3V126
Q9UI12
P48436
PDB IDs
1S9M
1SX9
4EUW
Enriched GO Terms of Interacting Partners
?
Regulation Of Cell Proliferation Involved In Tissue Homeostasis
Epithelial Cell Proliferation Involved In Prostatic Bud Elongation
Retinal Rod Cell Differentiation
Primary Prostatic Bud Elongation
Male Germ-line Sex Determination
Renal Vesicle Induction
Primary Sex Determination
Astrocyte Fate Commitment
Positive Regulation Of Extracellular Matrix Assembly
Metanephric Nephron Tubule Formation
Intestinal Epithelial Structure Maintenance
Intrahepatic Bile Duct Development
Positive Regulation Of Mesenchymal Stem Cell Differentiation
Negative Regulation Of Photoreceptor Cell Differentiation
Cellular Response To Heparin
Sulfide Oxidation, Using Sulfide:quinone Oxidoreductase
Regulation Of Extracellular Matrix Assembly
Ureter Urothelium Development
Hydrogen Sulfide Metabolic Process
Response To Heparin
Ureter Morphogenesis
Ureter Smooth Muscle Cell Differentiation
Chondrocyte Hypertrophy
Metanephric Tubule Formation
Regulation Of Mesenchymal Stem Cell Differentiation
Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis
Common Bile Duct Development
Metanephric Nephron Tubule Morphogenesis
Limb Bud Formation
Otic Vesicle Formation
Positive Regulation Of Male Gonad Development
Otic Vesicle Morphogenesis
Regulation Of Branching Involved In Lung Morphogenesis
Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis
Negative Regulation Of Mesenchymal Cell Apoptotic Process
Metanephric Tubule Morphogenesis
Cellular Response To Organonitrogen Compound
Camera-type Eye Photoreceptor Cell Differentiation
Sulfur Amino Acid Catabolic Process
Male Sex Determination
Maintenance Of Gastrointestinal Epithelium
Otic Vesicle Development
Ureter Development
ERK1 And ERK2 Cascade
Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis
Heart Valve Formation
Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis
Metanephric Nephron Tubule Development
Nephron Tubule Formation
Epithelial Structure Maintenance
Positive Regulation Of Transcription, DNA-templated
Transcription From RNA Polymerase II Promoter
Viral Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Cellular Metabolic Process
Regulation Of Cellular Response To Heat
N-terminal Peptidyl-lysine Acetylation
Transcription, DNA-templated
Notch Signaling Pathway
RNA Metabolic Process
RNA Biosynthetic Process
Response To Organic Substance
Transcription Initiation From RNA Polymerase II Promoter
Gene Expression
Cellular Response To Organic Substance
Nucleobase-containing Compound Metabolic Process
Regulation Of Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Gene Expression
Negative Regulation Of Cellular Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Cellular Response To Heat
DNA-templated Transcription, Initiation
Cellular Response To Stimulus
Signal Transduction
Regulation Of Cell Differentiation
Cell Surface Receptor Signaling Pathway
Regulation Of Transcription, DNA-templated
Protein Stabilization
Nitrogen Compound Metabolic Process
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
N-terminal Protein Amino Acid Acetylation
Signaling
Rhythmic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Metabolic Process
Negative Regulation Of RNA Biosynthetic Process
Cell Communication
Response To Heat
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Response To Unfolded Protein
Tagcloud
?
atoh1
atoh1a
atoh1and
conditional
coregulate
crest
determinant
ear
elusive
eya2
fate
fgf
fgfr
fgfs
ganglia
hair
ontogeny
otic
postfertilization
sag
segmentation
seq
sox9a
specify
statoacoustic
tlx2
ultricular
uncovered
zebrafish
Tagcloud (Difference)
?
atoh1
atoh1a
atoh1and
conditional
coregulate
crest
determinant
ear
elusive
eya2
fate
fgf
fgfr
fgfs
ganglia
hair
ontogeny
otic
postfertilization
sag
segmentation
seq
sox9a
specify
statoacoustic
tlx2
ultricular
uncovered
zebrafish
Tagcloud (Intersection)
?