CINP and PRC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CINP	PRC1
Description		cyclin dependent kinase 2 interacting protein	protein regulator of cytokinesis 1
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GO Annotations	Cellular Component	Nucleus	Spindle Pole Nucleus Nucleoplasm Chromosome Cytoplasm Spindle Cytosol Cytoskeleton Microtubule Spindle Microtubule Plasma Membrane Microtubule Cytoskeleton Midbody Intercellular Bridge Contractile Ring Mitotic Spindle Midzone
	Molecular Function	Protein Binding Preribosome Binding	Protein Binding Microtubule Binding Kinesin Binding Protein Kinase Binding Identical Protein Binding
	Biological Process	DNA Replication DNA Repair DNA Damage Response Ribosome Biogenesis Ribosomal Large Subunit Biogenesis Cell Division	Mitotic Spindle Elongation Microtubule Cytoskeleton Organization Positive Regulation Of Cell Population Proliferation Regulation Of Cytokinesis Mitotic Spindle Midzone Assembly Cell Division
Pathways			RHO GTPases activate CIT
Drugs
Diseases
GWAS		Body mass index ( 26426971) Refractive error ( 32231278)	Breast cancer ( 25038754 29059683) Mean platelet volume ( 27863252 32888494) Multisite chronic pain ( 31194737 33830993) Red cell distribution width ( 32888494) Type 2 diabetes ( 20581827 22885922 24509480 26818947 28869590 30054458 30297969 30718926 32499647)
Interacting Genes		43 interacting genes: AIRIM AMOTL2 APP ATRIP BAALC BLZF1 BTBD2 CCDC112 CCDC33 CDK2 CFAP161 CLUAP1 COG3 DRC4 FAM161B FBF1 FNDC11 GOLGA2 HNRNPD INCA1 KANK2 MAGEA3 MEOX2 MINAR1 MMADHC MZT1 NDUFB7 PATJ PAX6 POU6F2 PRC1 PRRX1 PSMA1 REL SERTAD1 SNRPD2 SP2 SYCE1 TEPSIN TXNRD3 ZBTB42 ZNF19 ZNF620	43 interacting genes: AKAP9 BICD2 CASK CCDC85B CCNA2 CCNB1 CCNE1 CDK1 CDK2 CEBPA CINP EMG1 EXOSC7 EXOSC8 FXR2 KIF3B KIF4A KLC2 KLC4 KRT20 LARP4 MAT2A NDEL1 NUDT16 OGT PBK PCM1 PKIA PLK1 PPIE RACGAP1 RBM10 RBM17 RBM22 RPA2 SF3B2 SLAIN1 SUMO2 TFIP11 THOC1 TRIM37 USHBP1 YWHAE
Entrez ID		51550	9055
HPRD ID		16715	17899
Ensembl ID		ENSG00000100865	ENSG00000198901
Uniprot IDs		Q9BW66	O43663
PDB IDs		8CIH 8RHN	3NRX 3NRY 4L3I 4L6Y 5KMG 7VBG
Enriched GO Terms of Interacting Partners?		Protein Binding	Microtubule-based Process Nucleic Acid Metabolic Process Organelle Organization Microtubule Cytoskeleton Organization G2/M Transition Of Mitotic Cell Cycle Cytoskeleton Cell Cycle G2/M Phase Transition Cytoskeleton Organization Nucleobase-containing Compound Metabolic Process Microtubule Cytoskeleton Organization Involved In Mitosis Regulation Of Cell Cycle Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Cycle Process Mitotic Cell Cycle Phase Transition Cytoplasm G1/S Transition Of Mitotic Cell Cycle Regulation Of Intracellular Protein Transport MRNA Metabolic Process Cell Cycle G1/S Phase Transition Nucleoplasm Nucleus Cell Cycle Phase Transition Centrosome Separation Centrosome Spindle Microtubule Microtubule Organizing Center RNA Metabolic Process Regulation Of Intracellular Transport Cyclin-dependent Protein Kinase Holoenzyme Complex Regulation Of Ubiquitin-dependent Protein Catabolic Process Kinesin Complex Cyclin A2-CDK1 Complex Cyclin B1-CDK1 Complex Regulation Of G2/M Transition Of Mitotic Cell Cycle MRNA Splicing, Via Spliceosome Regulation Of Proteasomal Protein Catabolic Process RNA Binding Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Nucleocytoplasmic Transport RNA Splicing, Via Transesterification Reactions Cell Division Cyclin A2-CDK2 Complex Cyclin E1-CDK2 Complex Cyclin-dependent Protein Kinase Activity U5 SnRNA 3'-end Processing U1 SnRNA 3'-end Processing Regulation Of Mitotic Cell Cycle Phase Transition Protein Localization To Organelle Regulation Of Attachment Of Spindle Microtubules To Kinetochore Mitotic DNA Damage Checkpoint Signaling
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