CINP and TXNRD3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CINP	TXNRD3
Description		cyclin dependent kinase 2 interacting protein	thioredoxin reductase 3
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GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol
	Molecular Function	Protein Binding Preribosome Binding	Thioredoxin-disulfide Reductase (NADPH) Activity Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On A Sulfur Group Of Donors, NAD(P) As Acceptor Flavin Adenine Dinucleotide Binding
	Biological Process	DNA Replication DNA Repair DNA Damage Response Ribosome Biogenesis Ribosomal Large Subunit Biogenesis Cell Division	Spermatogenesis Cell Differentiation Cell Redox Homeostasis Cellular Oxidant Detoxification
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971) Refractive error ( 32231278)
Interacting Genes		43 interacting genes: AIRIM AMOTL2 APP ATRIP BAALC BLZF1 BTBD2 CCDC112 CCDC33 CDK2 CFAP161 CLUAP1 COG3 DRC4 FAM161B FBF1 FNDC11 GOLGA2 HNRNPD INCA1 KANK2 MAGEA3 MEOX2 MINAR1 MMADHC MZT1 NDUFB7 PATJ PAX6 POU6F2 PRC1 PRRX1 PSMA1 REL SERTAD1 SNRPD2 SP2 SYCE1 TEPSIN TXNRD3 ZBTB42 ZNF19 ZNF620	9 interacting genes: ANKRD36B BOLA1 BOLA2 BOLA2B CINP CTNNA3 FHL2 PACRGL SNAP29
Entrez ID		51550	114112
HPRD ID		16715
Ensembl ID		ENSG00000100865	ENSG00000197763
Uniprot IDs		Q9BW66	B4DRZ5 Q86VQ6
PDB IDs		8CIH 8RHN	3H8Q
Enriched GO Terms of Interacting Partners?		Protein Binding	Iron-sulfur Cluster Assembly Complex Iron-sulfur Cluster Assembly Cell Redox Homeostasis Intracellular Iron Ion Homeostasis [2Fe-2S] Cluster Assembly 2 Iron, 2 Sulfur Cluster Binding Iron-sulfur Cluster Binding Atrial Cardiac Muscle Cell Development Inorganic Ion Homeostasis Intracellular Monoatomic Ion Homeostasis Intracellular Monoatomic Cation Homeostasis Ciliary Pocket Membrane Monoatomic Ion Homeostasis Monoatomic Cation Homeostasis Intracellular Chemical Homeostasis Bundle Of His Cell-Purkinje Myocyte Adhesion Involved In Cell Communication Autophagosome Membrane Docking Cardiac Muscle Cell-cardiac Muscle Cell Adhesion Cellular Homeostasis Fascia Adherens Preribosome Binding Ventricular Cardiac Muscle Cell Development Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane
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