CINP and BTBD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CINP	BTBD2
Description		cyclin dependent kinase 2 interacting protein	BTB domain containing 2
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GO Annotations	Cellular Component	Nucleus	P-body Cytoplasm Cytosol
	Molecular Function	Protein Binding Preribosome Binding	Protein Binding
	Biological Process	DNA Replication DNA Repair DNA Damage Response Ribosome Biogenesis Ribosomal Large Subunit Biogenesis Cell Division	Neurogenesis
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971) Refractive error ( 32231278)	Mitochondrial DNA copy number (white blood cells) ( 30704525) Platelet count ( 27863252 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		43 interacting genes: AIRIM AMOTL2 APP ATRIP BAALC BLZF1 BTBD2 CCDC112 CCDC33 CDK2 CFAP161 CLUAP1 COG3 DRC4 FAM161B FBF1 FNDC11 GOLGA2 HNRNPD INCA1 KANK2 MAGEA3 MEOX2 MINAR1 MMADHC MZT1 NDUFB7 PATJ PAX6 POU6F2 PRC1 PRRX1 PSMA1 REL SERTAD1 SNRPD2 SP2 SYCE1 TEPSIN TXNRD3 ZBTB42 ZNF19 ZNF620	37 interacting genes: BRD7 CCDC90B CCNC CDK2 CINP COPS6 CRMP1 CUL3 DPPA4 EEF1A1 ERG28 FXR1 GAPDH GBP2 GDF9 IGSF21 KPNA2 MLH1 NGB NTAQ1 OSGIN1 PSMD5 PTN RBM48 RUNX1 SETDB1 SMAD1 SMAD2 TDP2 TGFBR1 TLE1 TOP1 TP53 TRIM5 UBR1 UNC119 ZNF512B
Entrez ID		51550	55643
HPRD ID		16715	12252
Ensembl ID		ENSG00000100865	ENSG00000133243
Uniprot IDs		Q9BW66	Q9BX70
PDB IDs		8CIH 8RHN	3NO8
Enriched GO Terms of Interacting Partners?		Protein Binding	Male Germ Cell Nucleus Transforming Growth Factor Beta Receptor Signaling Pathway I-SMAD Binding Homomeric SMAD Protein Complex Positive Regulation Of Gene Expression Disordered Domain Specific Binding Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Nucleoplasm Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway SMAD Protein Complex Trophoblast Cell Migration Peptidyl-serine Phosphorylation Heteromeric SMAD Protein Complex Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription Regulator Complex Gastrulation Embryonic Cleavage Positive Regulation Of Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Regulation Of Macromolecule Metabolic Process Regulation Of Protein Metabolic Process DNA-templated Transcription Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Female Gamete Generation Primary MiRNA Processing Co-SMAD Binding Mesenchyme Development Negative Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Neuroblast Proliferation Negative Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Dendrite Development Ubiquitin Protein Ligase Binding Mitotic G1 DNA Damage Checkpoint Signaling Negative Regulation Of Macromolecule Biosynthetic Process Chromatin Binding Mitotic G1/S Transition Checkpoint Signaling Regulation Of MiRNA Transcription Cell Fate Commitment Negative Regulation Of RNA Metabolic Process Positive Regulation Of Multicellular Organismal Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process DNA Metabolic Process Positive Regulation Of Type I Interferon Production Regulation Of MiRNA Metabolic Process
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