CASP5

Description		caspase 5
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Protein-containing Complex NLRP1 Inflammasome Complex
	Molecular Function	Cysteine-type Endopeptidase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity
	Biological Process	Proteolysis Apoptotic Process Substantia Nigra Development Interleukin-18-mediated Signaling Pathway Regulation Of Apoptotic Process Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of Inflammatory Response Protein Maturation Cellular Response To Mechanical Stimulus
Pathways		Pyroptosis CASP5 inflammasome assembly CASP5-mediated substrate cleavage
Drugs
Diseases
GWAS
Interacting Genes		3 interacting genes: MAX NLRP1 PPHLN1
Entrez ID		838
HPRD ID		04048
Ensembl ID		ENSG00000137757
Uniprot IDs		P51878
PDB IDs
Enriched GO Terms of Interacting Partners?		Myc-Max Complex Mad-Max Complex Protein Localization To Heterochromatin Positive Regulation Of Pyroptotic Inflammatory Response Self Proteolysis NLRP3 Inflammasome Complex NLRP1 Inflammasome Complex Cysteine-type Endopeptidase Activator Activity NLRP1 Inflammasome Complex Assembly Cellular Response To UV-B Canonical Inflammasome Complex Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process Pyroptotic Cell Death
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