REV1 and POLK

Number of citations of the paper that reports this interaction (PMID 19170759)
18

Data Source:
HPRD (in vitro)

		REV1	POLK
Gene Name		REV1, polymerase (DNA directed)	polymerase (DNA directed) kappa
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm	Nucleoplasm
	Molecular Function	Magnesium Ion Binding Damaged DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Deoxycytidyl Transferase Activity	Damaged DNA Binding DNA-directed DNA Polymerase Activity Metal Ion Binding
	Biological Process	DNA Replication DNA Repair Response To UV Error-prone Translesion Synthesis	DNA Replication DNA Repair Nucleotide-excision Repair, DNA Gap Filling DNA Biosynthetic Process
Pathways		DNA Damage Bypass Translesion synthesis by DNA polymerases bypassing lesion on DNA template Translesion synthesis by HREV1
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-Protein Interactions		8 interactors: FHL2 MAD2L2 POLDIP2 POLH POLI POLK POLL REV3L	3 interactors: RAD18 REV1 TRAIP
Entrez ID		51455	51426
HPRD ID		16202	09291
Ensembl ID		ENSG00000135945
Uniprot IDs		Q9UBZ9	Q9UBT6
PDB IDs		2EBW 2LSI 2LSK 2LSY 3GQC 3VU7 4BA9 4EXT 4GK0 4GK5	1T94 2LSI 2OH2 2W7O 2W7P 3IN5 3PZP 4BA9 4GK5
Enriched GO Terms of Interacting Partners?		DNA Biosynthetic Process DNA Repair DNA Replication Cellular Response To DNA Damage Stimulus DNA Metabolic Process Cellular Response To Stress Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Postreplication Repair Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Response To Stress Nitrogen Compound Metabolic Process Nucleotide-excision Repair DNA-dependent DNA Replication Cellular Response To Stimulus Atrial Cardiac Muscle Cell Development Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Error-prone Translesion Synthesis Negative Regulation Of APC-Cdc20 Complex Activity Negative Regulation Of Transcription By Competitive Promoter Binding Response To Stimulus Translesion Synthesis Response To UV-C Pyrimidine Dimer Repair DNA Damage Response, Signal Transduction Resulting In Transcription Somatic Hypermutation Of Immunoglobulin Genes Heart Trabecula Formation DNA Synthesis Involved In DNA Repair Negative Regulation Of Transcription Regulatory Region DNA Binding Somatic Diversification Of Immune Receptors Via Somatic Mutation Nucleotide-excision Repair, DNA Gap Filling Ventricular Cardiac Muscle Cell Development Negative Regulation Of Epithelial To Mesenchymal Transition Regulation Of Transcription Regulatory Region DNA Binding Mitochondrion Morphogenesis Heart Trabecula Morphogenesis Ventricular Cardiac Muscle Cell Differentiation	Response To UV Error-prone Translesion Synthesis Response To Light Stimulus Response To Radiation Translesion Synthesis Protein Ubiquitination DNA Repair Protein Modification By Small Protein Conjugation Negative Regulation Of DNA Recombination Postreplication Repair Cellular Response To DNA Damage Stimulus DNA Metabolic Process Response To Abiotic Stimulus Regulation Of DNA Recombination
Tagcloud ?		augment consequent delaying elusive emerged enhance enhancing facilitates fasting fate linking maintenance melanoma modifications modified node nutrient partner promising relief sensing short specialized starvation sumo2 suppressor therapies toxic turn	affordable brought collaboration collaborative community contributed convened coordinated county department drew emphasized engaged engagement forums goals meaningful mid organizations orientation priorities rural serving sharply surveys top ultimately wisconsin workgroups
Tagcloud (Difference) ?		augment consequent delaying elusive emerged enhance enhancing facilitates fasting fate linking maintenance melanoma modifications modified node nutrient partner promising relief sensing short specialized starvation sumo2 suppressor therapies toxic turn	affordable brought collaboration collaborative community contributed convened coordinated county department drew emphasized engaged engagement forums goals meaningful mid organizations orientation priorities rural serving sharply surveys top ultimately wisconsin workgroups
Tagcloud (Intersection) ?