POLK and REV1

Number of citations of the paper that reports this interaction (PMID 19170759)
18

Data Source:
HPRD (in vitro)

		POLK	REV1
Gene Name		polymerase (DNA directed) kappa	REV1, polymerase (DNA directed)
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm	Nucleoplasm
	Molecular Function	Damaged DNA Binding DNA-directed DNA Polymerase Activity Metal Ion Binding	Magnesium Ion Binding Damaged DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Deoxycytidyl Transferase Activity
	Biological Process	DNA Replication DNA Repair Nucleotide-excision Repair, DNA Gap Filling DNA Biosynthetic Process	DNA Replication DNA Repair Response To UV Error-prone Translesion Synthesis
Pathways			DNA Damage Bypass Translesion synthesis by DNA polymerases bypassing lesion on DNA template Translesion synthesis by HREV1
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972)
Protein-Protein Interactions		3 interactors: RAD18 REV1 TRAIP	8 interactors: FHL2 MAD2L2 POLDIP2 POLH POLI POLK POLL REV3L
Entrez ID		51426	51455
HPRD ID		09291	16202
Ensembl ID			ENSG00000135945
Uniprot IDs		Q9UBT6	Q9UBZ9
PDB IDs		1T94 2LSI 2OH2 2W7O 2W7P 3IN5 3PZP 4BA9 4GK5	2EBW 2LSI 2LSK 2LSY 3GQC 3VU7 4BA9 4EXT 4GK0 4GK5
Enriched GO Terms of Interacting Partners?		Response To UV Error-prone Translesion Synthesis Response To Light Stimulus Response To Radiation Translesion Synthesis Protein Ubiquitination DNA Repair Protein Modification By Small Protein Conjugation Negative Regulation Of DNA Recombination Postreplication Repair Cellular Response To DNA Damage Stimulus DNA Metabolic Process Response To Abiotic Stimulus Regulation Of DNA Recombination	DNA Biosynthetic Process DNA Repair DNA Replication Cellular Response To DNA Damage Stimulus DNA Metabolic Process Cellular Response To Stress Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Postreplication Repair Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Response To Stress Nitrogen Compound Metabolic Process Nucleotide-excision Repair DNA-dependent DNA Replication Cellular Response To Stimulus Atrial Cardiac Muscle Cell Development Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Error-prone Translesion Synthesis Negative Regulation Of APC-Cdc20 Complex Activity Negative Regulation Of Transcription By Competitive Promoter Binding Response To Stimulus Translesion Synthesis Response To UV-C Pyrimidine Dimer Repair DNA Damage Response, Signal Transduction Resulting In Transcription Somatic Hypermutation Of Immunoglobulin Genes Heart Trabecula Formation DNA Synthesis Involved In DNA Repair Negative Regulation Of Transcription Regulatory Region DNA Binding Somatic Diversification Of Immune Receptors Via Somatic Mutation Nucleotide-excision Repair, DNA Gap Filling Ventricular Cardiac Muscle Cell Development Negative Regulation Of Epithelial To Mesenchymal Transition Regulation Of Transcription Regulatory Region DNA Binding Mitochondrion Morphogenesis Heart Trabecula Morphogenesis Ventricular Cardiac Muscle Cell Differentiation
Tagcloud ?		affordable brought collaboration collaborative community contributed convened coordinated county department drew emphasized engaged engagement forums goals meaningful mid organizations orientation priorities rural serving sharply surveys top ultimately wisconsin workgroups	augment consequent delaying elusive emerged enhance enhancing facilitates fasting fate linking maintenance melanoma modifications modified node nutrient partner promising relief sensing short specialized starvation sumo2 suppressor therapies toxic turn
Tagcloud (Difference) ?		affordable brought collaboration collaborative community contributed convened coordinated county department drew emphasized engaged engagement forums goals meaningful mid organizations orientation priorities rural serving sharply surveys top ultimately wisconsin workgroups	augment consequent delaying elusive emerged enhance enhancing facilitates fasting fate linking maintenance melanoma modifications modified node nutrient partner promising relief sensing short specialized starvation sumo2 suppressor therapies toxic turn
Tagcloud (Intersection) ?