REV1 and POLL

Number of citations of the paper that reports this interaction (PMID 14657033)
90

Data Source:
HPRD (in vivo)

		REV1	POLL
Gene Name		REV1, polymerase (DNA directed)	polymerase (DNA directed), lambda
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm	Nucleus
	Molecular Function	Magnesium Ion Binding Damaged DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Deoxycytidyl Transferase Activity	DNA Binding DNA-directed DNA Polymerase Activity Lyase Activity Metal Ion Binding
	Biological Process	DNA Replication DNA Repair Response To UV Error-prone Translesion Synthesis	DNA Replication Nucleotide-excision Repair Somatic Hypermutation Of Immunoglobulin Genes DNA Biosynthetic Process
Pathways		DNA Damage Bypass Translesion synthesis by DNA polymerases bypassing lesion on DNA template Translesion synthesis by HREV1
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-Protein Interactions		8 interactors: FHL2 MAD2L2 POLDIP2 POLH POLI POLK POLL REV3L	22 interactors: APP CDK2 FAM9B FSD2 KRT40 KRTAP10-3 KRTAP10-7 LDOC1 MAGEA12 PCNA PNMA1 REV1 RPA1 SSX2IP TFCP2 TFIP11 TRIM23 UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2H
Entrez ID		51455	27343
HPRD ID		16202	09394
Ensembl ID		ENSG00000135945	ENSG00000166169
Uniprot IDs		Q9UBZ9	A8K860 Q9UGP5
PDB IDs		2EBW 2LSI 2LSK 2LSY 3GQC 3VU7 4BA9 4EXT 4GK0 4GK5	1NZP 1RZT 1XSL 1XSN 1XSP 2BCQ 2BCR 2BCS 2BCU 2BCV 2GWS 2JW5 2PFN 2PFO 2PFP 2PFQ 3C5F 3C5G 3HW8 3HWT 3HX0 3MDA 3MDC 3MGH 3MGI 3PML 3PMN 3PNC 3UPQ 3UQ0 3UQ2 4FO6
Enriched GO Terms of Interacting Partners?		DNA Biosynthetic Process DNA Repair DNA Replication Cellular Response To DNA Damage Stimulus DNA Metabolic Process Cellular Response To Stress Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Postreplication Repair Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Response To Stress Nitrogen Compound Metabolic Process Nucleotide-excision Repair DNA-dependent DNA Replication Cellular Response To Stimulus Atrial Cardiac Muscle Cell Development Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Error-prone Translesion Synthesis Negative Regulation Of APC-Cdc20 Complex Activity Negative Regulation Of Transcription By Competitive Promoter Binding Response To Stimulus Translesion Synthesis Response To UV-C Pyrimidine Dimer Repair DNA Damage Response, Signal Transduction Resulting In Transcription Somatic Hypermutation Of Immunoglobulin Genes Heart Trabecula Formation DNA Synthesis Involved In DNA Repair Negative Regulation Of Transcription Regulatory Region DNA Binding Somatic Diversification Of Immune Receptors Via Somatic Mutation Nucleotide-excision Repair, DNA Gap Filling Ventricular Cardiac Muscle Cell Development Negative Regulation Of Epithelial To Mesenchymal Transition Regulation Of Transcription Regulatory Region DNA Binding Mitochondrion Morphogenesis Heart Trabecula Morphogenesis Ventricular Cardiac Muscle Cell Differentiation	Protein K48-linked Ubiquitination Protein Polyubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Mitotic Cell Cycle Phase Transition Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Cycle Phase Transition Toll-like Receptor 4 Signaling Pathway Translesion Synthesis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity DNA Replication Cellular Response To Stress DNA Repair Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Toll-like Receptor Signaling Pathway Nucleotide-excision Repair, DNA Gap Filling Cellular Response To Oxygen Levels Response To Abiotic Stimulus Mitotic Cell Cycle Process Telomere Maintenance Via Semi-conservative Replication Pattern Recognition Receptor Signaling Pathway Postreplication Repair Innate Immune Response-activating Signal Transduction Protein K11-linked Ubiquitination Nuclear DNA Replication Telomere Maintenance Via Recombination Catabolic Process Mitotic Cell Cycle Activation Of Innate Immune Response Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle G1/S Transition Of Mitotic Cell Cycle Mitotic Recombination DNA Strand Elongation Involved In DNA Replication
Tagcloud ?		augment consequent delaying elusive emerged enhance enhancing facilitates fasting fate linking maintenance melanoma modifications modified node nutrient partner promising relief sensing short specialized starvation sumo2 suppressor therapies toxic turn	allotting answers city clinics coordination creating espcc hcp hierarchy hospitals hp institutional institutionalized intercommunication km meetings metropolitan mobility ncp organization outpatient overload pd pediatricians planning rotation seeing solutions valencia
Tagcloud (Difference) ?		augment consequent delaying elusive emerged enhance enhancing facilitates fasting fate linking maintenance melanoma modifications modified node nutrient partner promising relief sensing short specialized starvation sumo2 suppressor therapies toxic turn	allotting answers city clinics coordination creating espcc hcp hierarchy hospitals hp institutional institutionalized intercommunication km meetings metropolitan mobility ncp organization outpatient overload pd pediatricians planning rotation seeing solutions valencia
Tagcloud (Intersection) ?