REV1

Gene Name		REV1, polymerase (DNA directed)
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Gene Ontology Annotations	Cellular Component	Nucleoplasm
	Molecular Function	Magnesium Ion Binding Damaged DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Deoxycytidyl Transferase Activity
	Biological Process	DNA Replication DNA Repair Response To UV Error-prone Translesion Synthesis
Pathways		DNA Damage Bypass Translesion synthesis by DNA polymerases bypassing lesion on DNA template Translesion synthesis by HREV1
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972)
Protein-protein Interactions		8 interactors: FHL2 MAD2L2 POLDIP2 POLH POLI POLK POLL REV3L
Entrez ID		51455
HPRD ID		16202
Ensembl ID		ENSG00000135945
Uniprot IDs		Q9UBZ9
PDB IDs		2EBW 2LSI 2LSK 2LSY 3GQC 3VU7 4BA9 4EXT 4GK0 4GK5
Enriched GO Terms of Interacting Partners?		DNA Biosynthetic Process DNA Repair DNA Replication Cellular Response To DNA Damage Stimulus DNA Metabolic Process Cellular Response To Stress Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Postreplication Repair Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Response To Stress Nitrogen Compound Metabolic Process Nucleotide-excision Repair DNA-dependent DNA Replication Cellular Response To Stimulus Atrial Cardiac Muscle Cell Development Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Error-prone Translesion Synthesis Negative Regulation Of APC-Cdc20 Complex Activity Negative Regulation Of Transcription By Competitive Promoter Binding Response To Stimulus Translesion Synthesis Response To UV-C Pyrimidine Dimer Repair DNA Damage Response, Signal Transduction Resulting In Transcription Somatic Hypermutation Of Immunoglobulin Genes Heart Trabecula Formation DNA Synthesis Involved In DNA Repair Negative Regulation Of Transcription Regulatory Region DNA Binding Somatic Diversification Of Immune Receptors Via Somatic Mutation Nucleotide-excision Repair, DNA Gap Filling Ventricular Cardiac Muscle Cell Development Negative Regulation Of Epithelial To Mesenchymal Transition Regulation Of Transcription Regulatory Region DNA Binding Mitochondrion Morphogenesis Heart Trabecula Morphogenesis Ventricular Cardiac Muscle Cell Differentiation
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