RNF138 and QKI

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RNF138	QKI
Gene Name		ring finger protein 138, E3 ubiquitin protein ligase	QKI, KH domain containing, RNA binding
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Cytoplasm
	Molecular Function	Zinc Ion Binding Ligase Activity Protein Kinase Binding	MRNA Binding Protein Binding SH3 Domain Binding Poly(A) RNA Binding
	Biological Process	Wnt Signaling Pathway Protein Ubiquitination	Vasculogenesis MRNA Processing Regulation Of Translation Spermatid Development RNA Splicing Positive Regulation Of Gene Expression Myelination Muscle Cell Differentiation Long-chain Fatty Acid Biosynthetic Process MRNA Transport 3'-UTR-mediated MRNA Destabilization
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS			Response to TNF antagonist treatment ( 18615156)
Protein-Protein Interactions		13 interactors: APP C6orf165 LEF1 LNX2 PCBP4 QKI TAF9 TCF4 TRIM8 UBE2D2 UBE2D4 UBE2K UBE2W	34 interactors: APP ATXN1 C10orf10 CARM1 DAZ1 DAZ4 FUBP3 HCLS1 HNRNPH2 HNRNPK HNRNPLL IL7R NABP1 PCBP1 PCBP2 PCBP4 PRMT1 PSMF1 PTBP1 PTBP2 RALY RBFOX1 RBFOX2 RBM11 RBM14 RBM23 RBPMS RNF138 SERF2 SNRPA THAP1 U2AF2 USH1C WDR77
Entrez ID		51444	9444
HPRD ID		11508	06691
Ensembl ID		ENSG00000134758	ENSG00000112531
Uniprot IDs		Q8WVD3	Q8WY44 Q96PU8
PDB IDs			4JVH
Enriched GO Terms of Interacting Partners?		Protein K48-linked Ubiquitination Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Protein Modification Process Regulation Of Protein Binding Protein K11-linked Ubiquitination Protein Metabolic Process Positive Regulation Of Epithelial To Mesenchymal Transition Cellular Protein Metabolic Process Regulation Of Growth Face Morphogenesis Head Morphogenesis Regulation Of Proteolysis Regulation Of Protein Metabolic Process Regulation Of Binding Histone H3 Acetylation Response To Stress Face Development Positive Regulation Of Stem Cell Differentiation Regulation Of Epithelial To Mesenchymal Transition Body Morphogenesis Cellular Response To Stress Positive Regulation Of Gene Expression Muscle Cell Differentiation Regulation Of Viral Transcription Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Regulation Of Protein Processing Diencephalon Development Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Canonical Wnt Signaling Pathway 3'-UTR-mediated MRNA Destabilization Synaptic Growth At Neuromuscular Junction Negative Regulation Of Apoptotic Process In Bone Marrow Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Forebrain Development Posttranscriptional Regulation Of Gene Expression Odontogenesis Of Dentin-containing Tooth Regulation Of Cellular Protein Metabolic Process Histone Acetylation Positive Regulation Of Cell Growth Ubiquitin-dependent Protein Catabolic Process Internal Peptidyl-lysine Acetylation Muscle Structure Development Cellular Metabolic Process Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Neutrophil Differentiation	RNA Processing MRNA Processing MRNA Metabolic Process RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Regulation Of RNA Splicing Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Intracellular Estrogen Receptor Signaling Pathway Regulation Of RNA Metabolic Process Negative Regulation Of RNA Splicing Neuromuscular Process Controlling Balance Regulation Of MRNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome Cellular Metabolic Process Positive Regulation Of Gene Expression Neuromuscular Process Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Regulation Of Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Peptidyl-arginine N-methylation Intracellular Receptor Signaling Pathway Histone Arginine Methylation Negative Regulation Of MRNA Splicing, Via Spliceosome Peptidyl-arginine Methylation Positive Regulation Of Cellular Metabolic Process Cellular Process Positive Regulation Of Metabolic Process Positive Regulation Of RNA Splicing Histone H3-R17 Methylation Regulation Of Myeloid Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Mitotic Cell Cycle Histone H3-R2 Methylation Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction Parallel Actin Filament Bundle Assembly Interleukin-7-mediated Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Visual Learning Visual Behavior
Tagcloud ?		20s aggravates bag6 d139e dnajb1 ef1a foetal hsp70s map1a map1b mesencephalic microtubule multifunctional neurones neuroprotection nigra ohda opn osteopontin pleiotrophin pull rgd sgtalpha sn substantia surviving utilised y165a yth	activate cal cancers clarify contribute currently cyclin d1 frequently malignancies mapk mitogen modulating newly occurring occurs oral oscc quaking regulative resulting shows squamous suppressor tumour uncontrolled underexpression unknown world
Tagcloud (Difference) ?		20s aggravates bag6 d139e dnajb1 ef1a foetal hsp70s map1a map1b mesencephalic microtubule multifunctional neurones neuroprotection nigra ohda opn osteopontin pleiotrophin pull rgd sgtalpha sn substantia surviving utilised y165a yth	activate cal cancers clarify contribute currently cyclin d1 frequently malignancies mapk mitogen modulating newly occurring occurs oral oscc quaking regulative resulting shows squamous suppressor tumour uncontrolled underexpression unknown world
Tagcloud (Intersection) ?