RNF138 and C6orf165

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RNF138	C6orf165
Gene Name		ring finger protein 138, E3 ubiquitin protein ligase	chromosome 6 open reading frame 165
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus
	Molecular Function	Zinc Ion Binding Ligase Activity Protein Kinase Binding
	Biological Process	Wnt Signaling Pathway Protein Ubiquitination
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: APP C6orf165 LEF1 LNX2 PCBP4 QKI TAF9 TCF4 TRIM8 UBE2D2 UBE2D4 UBE2K UBE2W	25 interactors: ADAMTSL4 AES APIP BANP C1orf94 CEP57L1 GFAP GLYR1 GPRASP2 GSE1 KLHL3 KRT31 KRT40 KRTAP13-1 LZTS2 MDFI RNF138 ROCK1 SAMD3 SOX30 TCF12 TFIP11 TMCC2 UBXN11 USHBP1
Entrez ID		51444	154313
HPRD ID		11508	12863
Ensembl ID		ENSG00000134758	ENSG00000272514
Uniprot IDs		Q8WVD3	Q8IYR0 Q8N771
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein K48-linked Ubiquitination Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Protein Modification Process Regulation Of Protein Binding Protein K11-linked Ubiquitination Protein Metabolic Process Positive Regulation Of Epithelial To Mesenchymal Transition Cellular Protein Metabolic Process Regulation Of Growth Face Morphogenesis Head Morphogenesis Regulation Of Proteolysis Regulation Of Protein Metabolic Process Regulation Of Binding Histone H3 Acetylation Response To Stress Face Development Positive Regulation Of Stem Cell Differentiation Regulation Of Epithelial To Mesenchymal Transition Body Morphogenesis Cellular Response To Stress Positive Regulation Of Gene Expression Muscle Cell Differentiation Regulation Of Viral Transcription Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Regulation Of Protein Processing Diencephalon Development Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Canonical Wnt Signaling Pathway 3'-UTR-mediated MRNA Destabilization Synaptic Growth At Neuromuscular Junction Negative Regulation Of Apoptotic Process In Bone Marrow Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Forebrain Development Posttranscriptional Regulation Of Gene Expression Odontogenesis Of Dentin-containing Tooth Regulation Of Cellular Protein Metabolic Process Histone Acetylation Positive Regulation Of Cell Growth Ubiquitin-dependent Protein Catabolic Process Internal Peptidyl-lysine Acetylation Muscle Structure Development Cellular Metabolic Process Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Neutrophil Differentiation
Tagcloud ?		20s aggravates bag6 d139e dnajb1 ef1a foetal hsp70s map1a map1b mesencephalic microtubule multifunctional neurones neuroprotection nigra ohda opn osteopontin pleiotrophin pull rgd sgtalpha sn substantia surviving utilised y165a yth
Tagcloud (Difference) ?		20s aggravates bag6 d139e dnajb1 ef1a foetal hsp70s map1a map1b mesencephalic microtubule multifunctional neurones neuroprotection nigra ohda opn osteopontin pleiotrophin pull rgd sgtalpha sn substantia surviving utilised y165a yth
Tagcloud (Intersection) ?