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TRAPPC4 and SDC2
Number of citations of the paper that reports this interaction (PMID
11018053
)
23
Data Source:
HPRD
(two hybrid, in vivo, in vitro)
TRAPPC4
SDC2
Gene Name
trafficking protein particle complex 4
syndecan 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Endoplasmic Reticulum
Golgi Stack
Cis-Golgi Network
Synaptic Vesicle
TRAPP Complex
Dendrite
Synapse
Golgi Lumen
Plasma Membrane
Integral Component Of Membrane
Neuronal Cell Body
Lysosomal Lumen
Synapse
Molecular Function
Protein Binding
Rab Guanyl-nucleotide Exchange Factor Activity
Protein Binding
PDZ Domain Binding
Biological Process
ER To Golgi Vesicle-mediated Transport
Dendrite Development
Extracellular Matrix Organization
Positive Regulation Of Rab GTPase Activity
Retinoid Metabolic Process
Response To Hypoxia
Carbohydrate Metabolic Process
Glycosaminoglycan Biosynthetic Process
Glycosaminoglycan Catabolic Process
Axon Guidance
Phototransduction, Visible Light
Biological_process
Pathogenesis
Extracellular Matrix Organization
Glycosaminoglycan Metabolic Process
Chondroitin Sulfate Metabolic Process
Response To Caffeine
Wound Healing
Small Molecule Metabolic Process
Ephrin Receptor Signaling Pathway
Dendrite Morphogenesis
Regulation Of Dendrite Morphogenesis
Pathways
Syndecan interactions
Non-integrin membrane-ECM interactions
MPS IIIB - Sanfilippo syndrome B
Diseases of glycosylation
Axon guidance
Defective B4GALT7 causes EDS, progeroid type
Heparan sulfate/heparin (HS-GAG) metabolism
MPS I - Hurler syndrome
MPS IX - Natowicz syndrome
Chondroitin sulfate/dermatan sulfate metabolism
Defective SLC26A2 causes chondrodysplasias
Glycosaminoglycan metabolism
EPHB-mediated forward signaling
Defective CHST14 causes EDS, musculocontractural type
Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
Defective PAPSS2 causes SEMD-PA
MPS IIIA - Sanfilippo syndrome A
Myoclonic epilepsy of Lafora
Defective CHST6 causes MCDC1
Glycogen storage diseases
MPS IIID - Sanfilippo syndrome D
EPH-Ephrin signaling
A tetrasaccharide linker sequence is required for GAG synthesis
MPS IIIC - Sanfilippo syndrome C
Retinoid metabolism and transport
Diseases associated with glycosaminoglycan metabolism
Mucopolysaccharidoses
Defective EXT2 causes exostoses 2
MPS II - Hunter syndrome
Defective B3GAT3 causes JDSSDHD
Defective CHST3 causes SEDCJD
Non-integrin membrane-ECM interactions
Diseases associated with visual transduction
Defective EXT1 causes exostoses 1, TRPS2 and CHDS
Syndecan interactions
MPS IV - Morquio syndrome A
Visual phototransduction
MPS IV - Morquio syndrome B
Defective CHSY1 causes TPBS
MPS VII - Sly syndrome
Metabolism of carbohydrates
HS-GAG biosynthesis
HS-GAG degradation
MPS VI - Maroteaux-Lamy syndrome
Drugs
Diseases
GWAS
Protein-Protein Interactions
12 interactors:
APP
PRSS23
SDC2
TFIP11
TRAPPC10
TRAPPC11
TRAPPC12
TRAPPC2
TRAPPC2L
TRAPPC3L
TRAPPC8
TRAPPC9
26 interactors:
BAG6
CASK
CSF2
CYP2C18
EPHB2
EZR
FGF2
FN1
HGF
KAL1
LAMA3
NF1
PF4
PPP3CC
PRKCA
PRKCB
PRKCG
REG3A
SDCBP
SERPINA1
SERPINC1
SPARC
TGFB1
TGFBR3
TNFSF13
TRAPPC4
Entrez ID
51399
6383
HPRD ID
18220
00803
Ensembl ID
ENSG00000196655
ENSG00000169439
Uniprot IDs
B4DME1
J3KP27
Q9Y296
E9PBI9
P34741
PDB IDs
2J3T
2JSN
2ZMV
Enriched GO Terms of Interacting Partners
?
Vesicle-mediated Transport
Golgi Vesicle Transport
ER To Golgi Vesicle-mediated Transport
Cytoplasmic Transport
Spliceosomal Complex Disassembly
Intracellular Transport
Transport
CVT Pathway
Synaptic Growth At Neuromuscular Junction
Collateral Sprouting In Absence Of Injury
Peroxisome Degradation
Establishment Of Localization In Cell
Dendrite Development
Collateral Sprouting
Axon Midline Choice Point Recognition
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Regulation Of Body Fluid Levels
Platelet Activation
Wound Healing
Response To Wounding
Blood Coagulation
Hemostasis
Extracellular Matrix Organization
Extracellular Structure Organization
Platelet Degranulation
Regulation Of Epithelial Cell Proliferation
Cell Activation
Regulation Of Angiogenesis
Regulation Of Cell Migration
Multicellular Organismal Development
Regulation Of Epithelial Cell Migration
Response To External Stimulus
Regulation Of Cell Motility
Regulation Of Cell Proliferation
Response To Stimulus
Regulation Of Locomotion
Regulation Of Cellular Component Movement
Locomotion
Positive Regulation Of Signal Transduction
System Development
Developmental Process
Negative Regulation Of Cellular Protein Metabolic Process
Regulation Of Endothelial Cell Migration
Anatomical Structure Development
Chemotaxis
Movement Of Cell Or Subcellular Component
Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation Of Protein Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Negative Regulation Of Epithelial Cell Proliferation
Regulation Of Wound Healing
Regulation Of Cell Differentiation
Regulation Of Cellular Protein Metabolic Process
Cell Differentiation
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Response To Stress
Positive Regulation Of Endothelial Cell Migration
Regulation Of Cellular Process
Positive Regulation Of DNA Metabolic Process
Positive Regulation Of Epithelial Cell Proliferation
Cell Morphogenesis Involved In Differentiation
Regulation Of Protein Metabolic Process
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Positive Regulation Of Cell Migration
Cell Development
Histone H3-T6 Phosphorylation
Tagcloud
?
affymetrix
akt2
aroused
bioinformatics
ccng2
ccnu
cdkn2c
chemosensitivity
ep300
excavate
gbm
id2
igfbp3
map2k2
mdm4
pdgfd
perfected
picked
plethora
prkca
raf1
rbl1
rigorous
semustine
socs2
stmn1
tcf7l1
tubb
unsatisfactory
Tagcloud (Difference)
?
affymetrix
akt2
aroused
bioinformatics
ccng2
ccnu
cdkn2c
chemosensitivity
ep300
excavate
gbm
id2
igfbp3
map2k2
mdm4
pdgfd
perfected
picked
plethora
prkca
raf1
rbl1
rigorous
semustine
socs2
stmn1
tcf7l1
tubb
unsatisfactory
Tagcloud (Intersection)
?