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SDC2 and CSF2
Number of citations of the paper that reports this interaction (PubMedID
10734053
)
0
Data Source:
HPRD
(in vivo)
SDC2
CSF2
Description
syndecan 2
colony stimulating factor 2
Image
GO Annotations
Cellular Component
Endoplasmic Reticulum Lumen
Golgi Lumen
Plasma Membrane
Cell Surface
Membrane
Extracellular Matrix
Lysosomal Lumen
Extracellular Region
Extracellular Space
Plasma Membrane
Granulocyte Macrophage Colony-stimulating Factor Receptor Complex
Molecular Function
Protein Binding
PDZ Domain Binding
Identical Protein Binding
Cytokine Activity
Granulocyte Macrophage Colony-stimulating Factor Receptor Binding
Protein Binding
Growth Factor Activity
Biological Process
Nervous System Development
Cell Migration
Cell Differentiation
Dendrite Morphogenesis
Regulation Of Dendrite Morphogenesis
Histamine Secretion
Embryonic Placenta Development
Immune Response
Signal Transduction
Cell Surface Receptor Signaling Pathway Via JAK-STAT
Cell Population Proliferation
Positive Regulation Of Cell Population Proliferation
Regulation Of Signal Transduction
Regulation Of Gene Expression
Positive Regulation Of Gene Expression
Positive Regulation Of Macrophage Derived Foam Cell Differentiation
Myeloid Cell Differentiation
Neutrophil Differentiation
Monocyte Differentiation
Macrophage Differentiation
Positive Regulation Of Cell Migration
Positive Regulation Of Interleukin-23 Production
Response To Silicon Dioxide
Response To Fluid Shear Stress
Granulocyte-macrophage Colony-stimulating Factor Signaling Pathway
Epithelial Fluid Transport
Regulation Of Cell Population Proliferation
Myeloid Dendritic Cell Differentiation
Regulation Of Circadian Sleep/wake Cycle, Sleep
Negative Regulation Of DNA-templated Transcription
Regulation Of Developmental Process
Positive Regulation Of Leukocyte Proliferation
Cellular Response To Lipopolysaccharide
Positive Regulation Of Podosome Assembly
Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus
Dendritic Cell Differentiation
Cell Surface Receptor Signaling Pathway Via STAT
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways
Glycosaminoglycan-protein linkage region biosynthesis
HS-GAG biosynthesis
HS-GAG biosynthesis
HS-GAG degradation
Cell surface interactions at the vascular wall
Syndecan interactions
Syndecan interactions
Defective B4GALT7 causes EDS, progeroid type
Defective B3GAT3 causes JDSSDHD
Defective EXT2 causes exostoses 2
Defective EXT1 causes exostoses 1, TRPS2 and CHDS
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
EPHB-mediated forward signaling
Defective B3GALT6 causes EDSP2 and SEMDJL1
Post-translational protein phosphorylation
Attachment and Entry
Attachment and Entry
Retinoid metabolism and transport
Respiratory syncytial virus (RSV) attachment and entry
RSV-host interactions
Interleukin-3, Interleukin-5 and GM-CSF signaling
RAF/MAP kinase cascade
Interleukin-10 signaling
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells
Interleukin receptor SHC signaling
Drugs
Sargramostim
KB002
Diseases
GWAS
Post-traumatic stress disorder (
26114229
)
Refractive error (
32231278
)
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Crohn's disease (
28067908
)
Inflammatory bowel disease (
23128233
28067908
)
Rheumatoid arthritis (
22446963
24390342
30423114
)
Subcortical volume (MOSTest) (
32665545
)
Ulcerative colitis (
28067908
)
Interacting Genes
29 interacting genes:
ANOS1
ASPH
BAG6
CASK
CSF2
CYP2C18
EPHB2
EZR
FGF2
FN1
HGF
ITGB4
LAMA3
NF1
PF4
PPP3CC
PRKCA
PRKCB
PRKCG
REG3A
SDCBP
SERPINA1
SERPINC1
SPARC
TGFB1
TGFBR3
TNFSF13
TRAPPC4
UBC
9 interacting genes:
CSF2RA
CSF2RB
IL3RA
KITLG
MEOX2
PRG2
S100A6
S100P
SDC2
Entrez ID
6383
1437
HPRD ID
00803
00734
Ensembl ID
ENSG00000169439
ENSG00000164400
Uniprot IDs
E9PBI9
P34741
P04141
PDB IDs
6ITH
1CSG
2GMF
4NKQ
4RS1
5C7X
5D70
5D71
5D72
6BFQ
6BFS
Enriched GO Terms of Interacting Partners
?
Extracellular Space
Regulation Of Multicellular Organismal Process
Platelet Alpha Granule Lumen
Extracellular Region
Regulation Of Developmental Process
Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity
Regulation Of Cell Population Proliferation
Positive Regulation Of Cell Migration
Regulation Of ERK1 And ERK2 Cascade
Regulation Of Cell Migration
Positive Regulation Of Cell Motility
Positive Regulation Of Locomotion
Regulation Of Cell Motility
Regulation Of Locomotion
Positive Regulation Of Developmental Process
Regulation Of Anatomical Structure Morphogenesis
Regulation Of MAPK Cascade
Regulation Of Wound Healing
Positive Regulation Of Multicellular Organismal Process
Positive Regulation Of Cell Population Proliferation
Regulation Of Epithelial Cell Proliferation
Regulation Of Multicellular Organismal Development
Heparin Binding
Signaling Receptor Binding
Positive Regulation Of Gene Expression
Extracellular Matrix
Regulation Of Response To Wounding
Basement Membrane
Signal Transduction
Regulation Of Endothelial Cell Migration
Positive Regulation Of Metabolic Process
Regulation Of Cell Communication
Regulation Of Vasculature Development
Response To Wounding
Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Blood Vessel Endothelial Cell Migration
Positive Regulation Of Endothelial Cell Migration
Anatomical Structure Morphogenesis
Plasma Membrane
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Positive Regulation Of Macrophage Differentiation
Regulation Of Vesicle-mediated Transport
Histone H3T6 Kinase Activity
Diacylglycerol-dependent Serine/threonine Kinase Activity
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation Of Epithelial Cell Proliferation
Positive Regulation Of Signal Transduction
Interleukin-3 Receptor Activity
Granulocyte Macrophage Colony-stimulating Factor Receptor Complex
Granulocyte-macrophage Colony-stimulating Factor Signaling Pathway
Regulation Of Macrophage Cytokine Production
Cytokine Receptor Activity
External Side Of Plasma Membrane
Interleukin-3-mediated Signaling Pathway
Cellular Response To Interleukin-3
Extracellular Matrix
Signaling Receptor Activity
Regulation Of Cytokine Production Involved In Immune Response
Positive Regulation Of Macrophage Cytokine Production
Cytokine-mediated Signaling Pathway
Positive Regulation Of Leukocyte Proliferation
Positive Regulation Of Myeloid Leukocyte Cytokine Production Involved In Immune Response
Cytokine Binding
Positive Regulation Of Bone Mineralization
Translation Termination Factor Activity
Cytoplasmic Translational Termination
Regulation Of Production Of Molecular Mediator Of Immune Response
Leukocyte Apoptotic Process
Positive Regulation Of Biomineral Tissue Development
Immune System Process
Positive Regulation Of Ossification
Neural Crest Cell Migration
Mesenchymal Cell Migration
Positive Regulation Of Cytokine Production
Positive Regulation Of Cell Population Proliferation
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Tagcloud (Difference)
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Tagcloud (Intersection)
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