TRAPPC4 and PRSS23

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TRAPPC4	PRSS23
Description		trafficking protein particle complex subunit 4	serine protease 23
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Golgi Apparatus Golgi Stack Cytosol Plasma Membrane Synaptic Vesicle Membrane TRAPP Complex Dendrite Vesicle Synapse Postsynaptic Membrane Presynaptic Active Zone Postsynaptic Density Membrane TRAPPII Protein Complex TRAPPIII Protein Complex	Extracellular Region Nucleus Endoplasmic Reticulum Lumen Extracellular Exosome
	Molecular Function	Protein Binding	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Coating Autophagy Vesicle-mediated Transport Dendrite Development COPII Vesicle Coating Vesicle Tethering	Proteolysis
Pathways		COPII-mediated vesicle transport Syndecan interactions RAB GEFs exchange GTP for GDP on RABs	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs		S-palmitoyl-L-cysteine
Diseases
GWAS			Blood urea nitrogen levels ( 31152163) Chronic obstructive pulmonary disease ( 30804561) FEV1 ( 30804560) Heel bone mineral density ( 28869591 30598549) Intraocular pressure ( 29617998 29785010) Lung function (FEV1) ( 28166213) Lung function (FEV1/FVC) ( 30804560) Peak expiratory flow ( 30804560)
Interacting Genes		8 interacting genes: APP PRSS23 SDC2 TFIP11 TRAPPC12 TRAPPC2 TRAPPC3L TRAPPC8	27 interacting genes: ACTG1 APP B2M CHP1 EFNA3 FXR1 GATD1 GRK6 HSPA4 MAPK8IP2 NCAPD3 NIPBL NOC4L ODF2L PDPK1 PHF23 PPIA RACGAP1 RECQL4 RPL4P5 SEC11C SHMT1 SLC25A6 TCF12 TMEM222 TRAPPC4 UBC
Entrez ID		51399	11098
HPRD ID		18220	07149
Ensembl ID		ENSG00000196655	ENSG00000150687
Uniprot IDs		B4DF86 E9PKS9 E9PQE8 J3KP27 Q9Y296	O95084
PDB IDs		2J3T 2JSN 2ZMV
Enriched GO Terms of Interacting Partners?		TRAPP Complex TRAPPIII Protein Complex COPII Vesicle Coating Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Tethering Vesicle Coating Golgi Vesicle Transport Intracellular Transport Vesicle-mediated Transport Protein-containing Complex Organization Cellular Localization Establishment Of Localization In Cell Endoplasmic Reticulum Lumen Vesicle Organization Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Endoplasmic Reticulum-Golgi Intermediate Compartment Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Golgi Lumen Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Golgi Organization Spliceosomal Complex Disassembly U2-type Post-mRNA Release Spliceosomal Complex Regulation Of Kinetochore Assembly Positive Regulation Of Protein Localization To Kinetochore Protein-containing Complex Assembly Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Golgi Apparatus Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon
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