TRAPPC4 and PRSS23

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TRAPPC4	PRSS23
Gene Name		trafficking protein particle complex 4	protease, serine, 23
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Golgi Stack Cis-Golgi Network Synaptic Vesicle TRAPP Complex Dendrite Synapse	Nucleus Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Rab Guanyl-nucleotide Exchange Factor Activity	Serine-type Endopeptidase Activity
	Biological Process	ER To Golgi Vesicle-mediated Transport Dendrite Development Extracellular Matrix Organization Positive Regulation Of Rab GTPase Activity	Proteolysis
Pathways		Syndecan interactions Non-integrin membrane-ECM interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: APP PRSS23 SDC2 TFIP11 TRAPPC10 TRAPPC11 TRAPPC12 TRAPPC2 TRAPPC2L TRAPPC3L TRAPPC8 TRAPPC9	25 interactors: ACTG1 APP B2M CHP1 EFNA3 FXR1 GRK6 HSPA4 MAPK8IP2 NCAPD3 NIPBL NOC4L ODF2L PDDC1 PDPK1 PHF23 PPIA RACGAP1 RECQL4 RPL4P5 SHMT1 SLC25A6 TCF12 TMEM222 TRAPPC4
Entrez ID		51399	11098
HPRD ID		18220	07149
Ensembl ID		ENSG00000196655	ENSG00000150687
Uniprot IDs		B4DME1 J3KP27 Q9Y296	B4E2J3 O95084
PDB IDs		2J3T 2JSN 2ZMV
Enriched GO Terms of Interacting Partners?		Vesicle-mediated Transport Golgi Vesicle Transport ER To Golgi Vesicle-mediated Transport Cytoplasmic Transport Spliceosomal Complex Disassembly Intracellular Transport Transport CVT Pathway Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Peroxisome Degradation Establishment Of Localization In Cell Dendrite Development Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis	Platelet Activation Blood Coagulation Hemostasis Cell Differentiation Cellular Component Assembly Regulation Of Body Fluid Levels Organelle Organization Wound Healing Multicellular Organismal Development Generation Of Neurons Cell Activation Dendrite Development System Development Response To Stress Response To Wounding Neurogenesis Mating Behavior Nervous System Development Regulation Of Protein Localization Response To Stimulus Neuron Projection Development Cell Development Developmental Process Cytokinesis, Initiation Of Separation Actomyosin Contractile Ring Assembly Uncoating Of Virus Mating Anatomical Structure Development Neuron Development Retina Homeostasis Movement Of Cell Or Subcellular Component Cell Morphogenesis Involved In Neuron Differentiation Protein Targeting To Mitochondrion Protein Complex Assembly Regulation Of Cellular Localization Immune System Process Platelet Degranulation Negative Regulation Of Rho-dependent Protein Serine/threonine Kinase Activity Synaptic Growth At Neuromuscular Junction Active Induction Of Host Immune Response By Virus Mitotic Sister Chromatid Segregation Protein Localization To Mitochondrion Protein Folding Cognition Neuron Projection Morphogenesis Positive Regulation Of Cellular Protein Metabolic Process Neuron Differentiation Mitotic Nuclear Division Sister Chromatid Segregation Regulation Of Establishment Of Protein Localization
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