ATP6V1D and HAUS1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ATP6V1D	HAUS1
Description		ATPase H+ transporting V1 subunit D	HAUS augmin like complex subunit 1
Image
GO Annotations	Cellular Component	Golgi Membrane Vacuolar Proton-transporting V-type ATPase, V1 Domain Nucleoplasm Cytoplasm Lysosomal Membrane Centrosome Cytosol Cytoskeleton Plasma Membrane Cilium Endosome Membrane Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Proton-transporting V-type ATPase Complex Specific Granule Membrane Cell Projection Extracellular Exosome Extrinsic Component Of Synaptic Vesicle Membrane	Spindle Pole Cytoplasm Centrosome Spindle Cytosol Cytoskeleton Microtubule HAUS Complex Mitotic Spindle Microtubule
	Molecular Function	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism	Protein Binding
	Biological Process	Monoatomic Ion Transport Vacuolar Acidification Lysosomal Lumen Acidification Regulation Of Macroautophagy Cell Projection Organization Endosomal Lumen Acidification Intracellular PH Reduction Cilium Assembly Protein Localization To Cilium Golgi Lumen Acidification Synaptic Vesicle Lumen Acidification Proton Transmembrane Transport	Centrosome Cycle Regulation Of Microtubule Nucleation Spindle Assembly Cell Division
Pathways		ROS and RNS production in phagocytes Neutrophil degranulation Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs		Tiludronic acid
Diseases
GWAS
Interacting Genes		6 interacting genes: GOLGA2 HAUS1 KRT27 NDC80 TOMM34 VPS52	82 interacting genes: AK8 ARFIP2 ATP6V1D BFSP2 BLOC1S6 BORCS6 C3orf62 CAGE1 CBY2 CCDC136 CCDC57 CCHCR1 CDR2 CENPP CEP170P1 CEP44 CEP55 CEP57L1 CEP63 CEP70 DCTN2 DMD DTNBP1 FAM161B FGFR1OP2 GOLGA2 HGS HOOK2 IFIT3 IFT20 INCA1 KDM1A KIFC3 KRT1 KRT15 KRT18 KRT19 KRT3 KRT31 KRT38 KRT40 KXD1 LDOC1 LURAP1 MAD1L1 MAGEA6 MCM10 MCM3 MED4 MED7 MIPOL1 MTUS2 NDC80 NECAB2 NINL NUP54 NUP62 ODAD1 PDE4DIP PIBF1 PKN1 POLR3C SPAG5 SSC5D STX11 SYCE1 SYCE3 TEAD4 TFIP11 TFPT TRAF1 TRIM23 TRIM27 TRIM54 TRIM69 TSG101 TXN2 USHBP1 VPS37C VPS52 WASHC3 ZNF471
Entrez ID		51382	115106
HPRD ID		16524	16385
Ensembl ID		ENSG00000100554	ENSG00000152240
Uniprot IDs		Q9Y5K8	Q96CS2
PDB IDs		6WLZ 6WM2 6WM3 6WM4 7U4T 7UNF	7SQK
Enriched GO Terms of Interacting Partners?		Spindle Assembly Meiotic Spindle Assembly Spindle Organization Meiotic Spindle Organization Membraneless Organelle Assembly Syntaxin Binding Centrosome Cycle Cytoskeleton Organization Microtubule Cytoskeleton Organization Microtubule Organizing Center Organization Cell Division Embryonic Ectodermal Digestive Tract Development Kinetochore Adaptor Activity Mitotic Spindle Organization G2/MI Transition Of Meiotic Cell Cycle Microtubule Cytoskeleton Organization Involved In Mitosis Positive Regulation Of Protein Glycosylation Spindle Pole Organelle Assembly Meiotic Cell Cycle Phase Transition Ndc80 Complex Spindle Assembly Involved In Female Meiosis I GARP Complex EARP Complex Ectodermal Cell Differentiation Skeletal Muscle Satellite Cell Proliferation Microtubule-based Process Golgi Disassembly Protein Targeting Regulation Of Protein Glycosylation Vesicle-mediated Cholesterol Transport HAUS Complex Microtubule Binding Importin-alpha Family Protein Binding Golgi Ribbon Formation Skeletal Muscle Cell Proliferation Golgi Cis Cisterna Golgi Vesicle Transport Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Spindle Assembly Involved In Female Meiosis Asymmetric Cell Division Organelle Organization Microtubule Mitotic Spindle Microtubule Positive Regulation Of Glycoprotein Metabolic Process Establishment Of Protein Localization Positive Regulation Of Glycoprotein Biosynthetic Process Golgi To Vacuole Transport Embryonic Digestive Tract Development Outer Kinetochore	Cytoskeleton Organelle Organization Centrosome Microtubule-based Process Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Cytoskeleton Organization Intermediate Filament Organization Protein Binding Structural Constituent Of Skin Epidermis Keratin Filament Organelle Assembly Intermediate Filament Identical Protein Binding Microtubule Organizing Center Organization Establishment Of Localization In Cell Supramolecular Fiber Organization Organelle Localization Intracellular Transport Centrosome Cycle Microtubule Binding Intracellular Protein Localization Protein Localization To Centrosome Metaphase Chromosome Alignment Cellular Component Assembly Protein Transport Cilium Organization Centriole Assembly Spindle Organization Cellular Localization Structural Molecule Activity Establishment Of Protein Localization Cilium Assembly Microtubule Establishment Of Organelle Localization Chromosome Localization BLOC-1 Complex Plasma Membrane Bounded Cell Projection Assembly Microtubule Cytoskeleton Organization Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cell Projection Assembly Mitotic Metaphase Chromosome Alignment Protein Localization To Cytoskeleton Spindle Pole Structural Constituent Of Cytoskeleton Vesicle Organization Centriole Centriole Replication Protein Localization To Organelle Endosomal Transport
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?