ATP6V1D

Description		ATPase H+ transporting V1 subunit D
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GO Annotations	Cellular Component	Golgi Membrane Vacuolar Proton-transporting V-type ATPase, V1 Domain Nucleoplasm Cytoplasm Lysosomal Membrane Centrosome Cytosol Cytoskeleton Plasma Membrane Cilium Endosome Membrane Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle Proton-transporting V-type ATPase Complex Specific Granule Membrane Cell Projection Extracellular Exosome Extrinsic Component Of Synaptic Vesicle Membrane
	Molecular Function	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Monoatomic Ion Transport Vacuolar Acidification Lysosomal Lumen Acidification Regulation Of Macroautophagy Cell Projection Organization Endosomal Lumen Acidification Intracellular PH Reduction Cilium Assembly Protein Localization To Cilium Golgi Lumen Acidification Synaptic Vesicle Lumen Acidification Proton Transmembrane Transport
Pathways		ROS and RNS production in phagocytes Neutrophil degranulation Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs		Tiludronic acid
Diseases
GWAS
Interacting Genes		6 interacting genes: GOLGA2 HAUS1 KRT27 NDC80 TOMM34 VPS52
Entrez ID		51382
HPRD ID		16524
Ensembl ID		ENSG00000100554
Uniprot IDs		Q9Y5K8
PDB IDs		6WLZ 6WM2 6WM3 6WM4 7U4T 7UNF
Enriched GO Terms of Interacting Partners?		Spindle Assembly Meiotic Spindle Assembly Spindle Organization Meiotic Spindle Organization Membraneless Organelle Assembly Syntaxin Binding Centrosome Cycle Cytoskeleton Organization Microtubule Cytoskeleton Organization Microtubule Organizing Center Organization Cell Division Embryonic Ectodermal Digestive Tract Development Kinetochore Adaptor Activity Mitotic Spindle Organization G2/MI Transition Of Meiotic Cell Cycle Microtubule Cytoskeleton Organization Involved In Mitosis Positive Regulation Of Protein Glycosylation Spindle Pole Organelle Assembly Meiotic Cell Cycle Phase Transition Ndc80 Complex Spindle Assembly Involved In Female Meiosis I GARP Complex EARP Complex Ectodermal Cell Differentiation Skeletal Muscle Satellite Cell Proliferation Microtubule-based Process Golgi Disassembly Protein Targeting Regulation Of Protein Glycosylation Vesicle-mediated Cholesterol Transport HAUS Complex Microtubule Binding Importin-alpha Family Protein Binding Golgi Ribbon Formation Skeletal Muscle Cell Proliferation Golgi Cis Cisterna Golgi Vesicle Transport Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Spindle Assembly Involved In Female Meiosis Asymmetric Cell Division Organelle Organization Microtubule Mitotic Spindle Microtubule Positive Regulation Of Glycoprotein Metabolic Process Establishment Of Protein Localization Positive Regulation Of Glycoprotein Biosynthetic Process Golgi To Vacuole Transport Embryonic Digestive Tract Development Outer Kinetochore
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