MEX3C and LINC00839

Number of citations of the paper that reports this interaction (PubMedID 30631154)
76

Data Source:
BioGRID (unspecified method, affinity chromatography technology)

		MEX3C	LINC00839
Description		mex-3 RNA binding family member C	long intergenic non-protein coding RNA 839
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Chondrocyte Hypertrophy Regulation Of Fat Cell Differentiation Energy Homeostasis
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Asthma ( 30929738) Asthma (childhood onset) ( 30929738) Asthma onset (childhood vs adult) ( 30929738) Atrial fibrillation ( 29892015 30061737) Femur bone mineral density x serum urate levels interaction ( 34046847) Immune response to anthrax vaccine ( 22658931) Immune response to smallpox vaccine (IL-6) ( 22610502) Metabolite levels ( 23823483) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) Systolic blood pressure ( 30224653 30578418) Weight ( 34074324)
Interacting Genes		6 interacting genes: LINC00839 PTEN SOCS3 UBE2D2 UBE2D3 UBE2L3	82 interacting genes: ADAMTS15 AKAP13 ALDH16A1 APOL3 BFSP1 CALM1 CC2D1B CCDC93 CDC16 CEP192 CEP295NL CHPF CIZ1 CLGN CLPTM1 COPB1 DNAH10 DPEP3 EFL1 EID2 EMX1 FAAP100 FAM13B FBXL5 HAPLN4 IQCN IRX4 JAKMIP2 KLK14 KRT1 KRT6B L1CAM LRTM3 MEX3A MEX3B MEX3C MEX3D MICAL2 MYO7A NDUFA2 NOC4L NOTCH3 NVL OS9 P4HB PABPN1 PALM3 PARP6 PHACTR1 PKD1L2 PLOD3 PNPLA3 POMT2 PRSS1 PRSS3 PTBP1 PTEN PTPRA QSOX2 RAPGEF6 RIF1 RPLP2 RPTOR RYR2 SEMA4D SEPTIN12 SEPTIN9 SERHL2 SLC7A14 SOWAHB SREBF2 SYNE1 SYNE3 TAS1R3 TCF24 TMC4 TRO UBE2S VANGL1 YAP1 YIPF1 ZFPL1
Entrez ID		51320	84856
HPRD ID		15255	17516
Ensembl ID		ENSG00000176624	ENSG00000185904
Uniprot IDs		Q5U5Q3
PDB IDs		5WWW 5WWX 5WWZ 5ZI6
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein Modification Process Protein Polyubiquitination Ubiquitin-protein Transferase Activity Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K11-linked Ubiquitination Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Establishment Of Protein Localization To Mitochondrion Positive Regulation Of Protein Targeting To Mitochondrion Post-translational Protein Modification Protein Autoubiquitination Negative Regulation Of Synaptic Vesicle Clustering Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Cytoplasmic Side Of Plasma Membrane Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Protein K48-linked Ubiquitination Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Phosphatidylinositol Phosphate Phosphatase Activity Proteolysis Involved In Protein Catabolic Process Protein Metabolic Process Regulation Of Synaptic Vesicle Clustering Platelet Dense Granule Membrane Negative Regulation Of Peptidyl-serine Phosphorylation Neuron-neuron Synaptic Transmission Negative Regulation Of Cell Size Anaphase-promoting Complex Binding Postsynaptic Density Assembly Forebrain Morphogenesis Presynaptic Membrane Assembly Nucleotide Binding Anterograde Axonal Protein Transport Ubiquitin-protein Transferase Activator Activity Cellular Response To Interleukin-17 Protein Tyrosine Kinase Inhibitor Activity Presynaptic Membrane Organization Branching Involved In Labyrinthine Layer Morphogenesis Postsynaptic Specialization Assembly Schmidt-Lanterman Incisure Negative Regulation Of Excitatory Postsynaptic Potential Locomotor Rhythm Cellular Response To Electrical Stimulus
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