HSPA14 and FAM107A

Number of citations of the paper that reports this interaction (PubMedID 28604741)
0

Data Source:
BioGRID (two hybrid)

		HSPA14	FAM107A
Description		heat shock protein family A (Hsp70) member 14	family with sequence similarity 107 member A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Ribosome Plasma Membrane Membrane	Stress Fiber Nucleus Cytoplasm Cytoskeleton Plasma Membrane Focal Adhesion Actin Cytoskeleton Membrane Nuclear Speck Ruffle Membrane Cell Projection Neuron Projection Synapse Anchoring Junction
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding ATP Hydrolysis Activity Heat Shock Protein Binding Protein Folding Chaperone ATP-dependent Protein Folding Chaperone	Actin Binding Protein Binding
	Biological Process	Protein Folding Protein Refolding 'de Novo' Cotranslational Protein Folding	Regulation Of Cell Growth Actin Filament Polymerization Positive Regulation Of Cell Migration Positive Regulation Of Protein Ubiquitination Regulation Of Protein Stability Cellular Response To Nutrient Levels Regulation Of Actin Cytoskeleton Organization Cognition Actin Filament Bundle Assembly Negative Regulation Of Focal Adhesion Assembly Regulation Of Microtubule Cytoskeleton Organization Cellular Response To Glucocorticoid Stimulus Negative Regulation Of Long-term Synaptic Potentiation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS		Night sleep phenotypes ( 27126917) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)	Blood protein levels ( 30072576) Night sleep phenotypes ( 27126917)
Interacting Genes		8 interacting genes: BARD1 BRCA1 CFTR DNAJC2 FAM107A OGT PAXIP1 STIP1	58 interacting genes: AGMAT APPBP2 AUH AZI2 BEGAIN BIRC8 CALCOCO2 CANX CCDC125 CCDC136 CCDC57 CCDC85B CPSF3 DAPK1 EFEMP2 EFHC2 EIF4A1 ESRRG FKBP6 FSD2 GFM2 GOLGA6L9 HFM1 HOOK2 HSF2BP HSPA14 HSPD1 HTRA1 IQUB ITPRID2 KRT15 KRT19 KRT27 KRT40 KRTAP4-12 LDOC1 LZTS2 MEIOB MID2 MTREX MTUS2 NEXN NFKBID NINL PLSCR1 PNMA1 POMP PSMD6 RAB18 RINT1 RNLS SPATA22 TADA2A TRAF2 TRIM37 USHBP1 VIM WDR47
Entrez ID		51182	11170
HPRD ID		07021	09753
Ensembl ID		ENSG00000187522	ENSG00000168309
Uniprot IDs		Q0VDF9	O95990 Q6IAM1
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin-modified Histone Reader Activity Histone H2AK127 Ubiquitin Ligase Activity Histone H2AK129 Ubiquitin Ligase Activity BRCA1-BARD1 Complex BRCA1-B Complex Nuclear Ubiquitin Ligase Complex BRCA1-C Complex BRCA1-A Complex Chromatin Organization Regulation Of Cell Cycle G2/M Phase Transition DNA Strand Resection Involved In Replication Fork Processing Regulation Of Cell Cycle Phase Transition Response To Ionizing Radiation Regulation Of DNA Metabolic Process Regulation Of DNA Damage Checkpoint Negative Regulation Of Mitotic Cell Cycle Phase Transition Protein K6-linked Ubiquitination Regulation Of Protein Ubiquitination Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Phase Transition Homologous Recombination DNA Recombination Regulation Of Post-translational Protein Modification DNA Metabolic Process Regulation Of Cell Cycle Process Negative Regulation Of Cell Cycle Process Protein-containing Complex Mitotic G2/M Transition Checkpoint Positive Regulation Of Protein Metabolic Process Nucleus Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of MRNA 3'-end Processing Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Cell Cycle G2/M Phase Transition Cellular Response To Ionizing Radiation Positive Regulation Of Macromolecule Metabolic Process Regulation Of Cell Cycle Response To Radiation Positive Regulation Of Anion Channel Activity Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Ubiquitination Ubiquitin Ligase Complex Positive Regulation Of Metabolic Process Regulation Of Mitotic Cell Cycle	Cytoskeleton Intermediate Filament Organization Intermediate Filament Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Microtubule Structural Constituent Of Skin Epidermis Meiosis I Cell Cycle Process Female Meiosis I Supramolecular Fiber Organization
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