HSPA14

Name	heat shock protein family A (Hsp70) member 14
Structure	No pdb structure
Interactors	8 interactors: BARD1 BRCA1 CFTR DNAJC2 FAM107A OGT PAXIP1 STIP1
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Ribosome Plasma Membrane Membrane
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding ATP Hydrolysis Activity Heat Shock Protein Binding Protein Folding Chaperone ATP-dependent Protein Folding Chaperone
	Biological Process	Protein Folding Protein Refolding 'de Novo' Cotranslational Protein Folding
Pathways	Regulation of HSF1-mediated heat shock response
GWAS	Night sleep phenotypes ( 27126917 ) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309 )
Entrez ID	51182
HPRD ID	07021
Ensembl ID	ENSG00000187522
Uniprot IDs	Q0VDF9
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Ubiquitin-modified Histone Reader Activity Histone H2AK127 Ubiquitin Ligase Activity Histone H2AK129 Ubiquitin Ligase Activity BRCA1-BARD1 Complex BRCA1-B Complex Nuclear Ubiquitin Ligase Complex BRCA1-C Complex BRCA1-A Complex Chromatin Organization Regulation Of Cell Cycle G2/M Phase Transition DNA Strand Resection Involved In Replication Fork Processing Regulation Of Cell Cycle Phase Transition Response To Ionizing Radiation Regulation Of DNA Metabolic Process Regulation Of DNA Damage Checkpoint Negative Regulation Of Mitotic Cell Cycle Phase Transition Protein K6-linked Ubiquitination Regulation Of Protein Ubiquitination Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Phase Transition Homologous Recombination DNA Recombination Regulation Of Post-translational Protein Modification DNA Metabolic Process Regulation Of Cell Cycle Process Negative Regulation Of Cell Cycle Process Protein-containing Complex Mitotic G2/M Transition Checkpoint Positive Regulation Of Protein Metabolic Process Nucleus Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of MRNA 3'-end Processing Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Cell Cycle G2/M Phase Transition Cellular Response To Ionizing Radiation Positive Regulation Of Macromolecule Metabolic Process Regulation Of Cell Cycle Response To Radiation Positive Regulation Of Anion Channel Activity Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Protein Ubiquitination Ubiquitin Ligase Complex Positive Regulation Of Metabolic Process Regulation Of Mitotic Cell Cycle