HSPA14 and DNAJC2

Number of citations of the paper that reports this interaction (PMID 16002468)
26

Data Source:
HPRD (in vitro)

		HSPA14	DNAJC2
Gene Name		heat shock 70kDa protein 14	DnaJ (Hsp40) homolog, subfamily C, member 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Ribosome Membrane	Nucleus Cytoplasm Cytosol Nuclear Membrane
	Molecular Function	Protein Binding ATP Binding	DNA Binding Chromatin Binding Hsp70 Protein Binding Histone Binding Ubiquitin Binding Poly(A) RNA Binding
	Biological Process	'de Novo' Cotranslational Protein Folding	DNA Replication Transcription, DNA-templated Chromatin Modification Negative Regulation Of Cell Growth Positive Regulation Of Transcription, DNA-templated 'de Novo' Cotranslational Protein Folding Negative Regulation Of DNA Biosynthetic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: BARD1 BRCA1 DNAJC2 PAXIP1 STIP1	2 interactors: HIST2H2AA3 HSPA14
Entrez ID		51182	27000
HPRD ID		07021	19072
Ensembl ID		ENSG00000187522	ENSG00000105821
Uniprot IDs		B0YIZ1 Q0VDF9 Q8TAQ0	Q99543
PDB IDs			2M2E
Enriched GO Terms of Interacting Partners?		Protein K6-linked Ubiquitination Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of Histone Acetylation Regulation Of Histone H3-K4 Methylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation DNA Metabolic Process Positive Regulation Of Histone Methylation Regulation Of Histone Acetylation Regulation Of Histone Methylation Positive Regulation Of Histone Modification DNA Damage Response, Signal Transduction By P53 Class Mediator DNA Repair Signal Transduction In Response To DNA Damage Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H3-K36 Methylation Positive Regulation Of Histone H4-K16 Acetylation Signal Transduction By P53 Class Mediator Regulation Of Histone Modification Positive Regulation Of Protein Ubiquitination Response To Ionizing Radiation Positive Regulation Of DNA Metabolic Process Negative Regulation Of MRNA 3'-end Processing 'de Novo' Cotranslational Protein Folding Positive Regulation Of Histone H3-K9 Acetylation Cellular Response To DNA Damage Stimulus Protein Polyubiquitination Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Regulation Of Chromosome Organization Regulation Of Protein Ubiquitination DNA Recombination Cellular Response To Indole-3-methanol Negative Regulation Of Centriole Replication Positive Regulation Of Protein Metabolic Process DNA Replication Negative Regulation Of Protein Export From Nucleus Dosage Compensation By Inactivation Of X Chromosome Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Chorion Development Regulation Of Histone H3-K9 Acetylation Positive Regulation Of Metabolic Process Response To Stress Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Stress Regulation Of Centriole Replication Positive Regulation Of Gene Expression	'de Novo' Cotranslational Protein Folding 'de Novo' Protein Folding
Tagcloud ?		apg1 forelimb forelimbs grp94 hindlimb hindlimbs hsp10 hsp105 hsp110 hsp20 hsp22 hsp25 hsp47 hsp60 hspb10 hspb2 hspb3 hspb4 hspb7 hspb9 hsps oligodactylic performs phocomelic trap1	actually bear categorized cerevisiae contain dnaja1 dnajb1b domains dubbed folding highlights homologs hsp40 hsp70s hydrolysis introduces named names preserved saccharomyces stabilizing stresses studying unfolding
Tagcloud (Difference) ?		apg1 forelimb forelimbs grp94 hindlimb hindlimbs hsp10 hsp105 hsp110 hsp20 hsp22 hsp25 hsp47 hsp60 hspb10 hspb2 hspb3 hspb4 hspb7 hspb9 hsps oligodactylic performs phocomelic trap1	actually bear categorized cerevisiae contain dnaja1 dnajb1b domains dubbed folding highlights homologs hsp40 hsp70s hydrolysis introduces named names preserved saccharomyces stabilizing stresses studying unfolding
Tagcloud (Intersection) ?