HN1 and SFPQ

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		HN1	SFPQ
Gene Name		hematological and neurological expressed 1	splicing factor proline/glutamine-rich
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Paraspeckles
	Molecular Function		Nucleotide Binding Transcription Regulatory Region Sequence-specific DNA Binding Core Promoter Binding Protein Binding Histone Deacetylase Binding Transcription Regulatory Region DNA Binding Poly(A) RNA Binding
	Biological Process	Developmental Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Alternative MRNA Splicing, Via Spliceosome DNA Repair DNA Recombination Transcription, DNA-templated MRNA Processing RNA Splicing Regulation Of Circadian Rhythm Negative Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Rhythmic Process Histone H3 Deacetylation Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Endometrial cancer ( 21499250)
Protein-Protein Interactions		2 interactors: ARHGAP44 SFPQ	27 interactors: APBB1 AR CSNK2A1 ERG EXOSC5 FHL2 FUS GAS7 HIST3H3 HN1 NONO PIN1 PPARG PPP1CA PRPF40A PSPC1 PTBP1 RAC1 SIN3A SMAD5 SNRPA SREK1 TCERG1 TOP1 UBC WBP4 ZMYM2
Entrez ID		51155	6421
HPRD ID		13665	07284
Ensembl ID		ENSG00000189159	ENSG00000116560
Uniprot IDs		Q9H3K0 Q9UK76	P23246 Q86VG2
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Oxidative Stress-induced Cell Death Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of Circadian Rhythm Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Histone H3 Deacetylation	RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Rhythmic Process Regulation Of Circadian Rhythm RNA Splicing MRNA Metabolic Process Transcription, DNA-templated MRNA Processing RNA Biosynthetic Process Cellular Metabolic Process Regulation Of Gene Expression Regulation Of Apoptotic Process RNA Processing Regulation Of Cell Death Cellular Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Circadian Rhythm Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Regulation Of Transcription, DNA-templated Intracellular Receptor Signaling Pathway Negative Regulation Of Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions DNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Cellular Component Organization Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Cell Cycle Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Biosynthetic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Cellular Biosynthetic Process
Tagcloud ?		100nm 48h 81m anapc13 calm2 carcinogenic diarrheic drawing exhaustive explanation malat1 mapre2 mllt11 molluscs oa okadaic pathologies poisoning positives pttg1 rodents sga shellfish shsy5y ssh subtractive tax1bp1 toxins tumourigenesis
Tagcloud (Difference) ?		100nm 48h 81m anapc13 calm2 carcinogenic diarrheic drawing exhaustive explanation malat1 mapre2 mllt11 molluscs oa okadaic pathologies poisoning positives pttg1 rodents sga shellfish shsy5y ssh subtractive tax1bp1 toxins tumourigenesis
Tagcloud (Intersection) ?