HN1 and ARHGAP44

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		HN1	ARHGAP44
Gene Name		hematological and neurological expressed 1	Rho GTPase activating protein 44
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Cytosol Cell Junction Leading Edge Membrane Dendritic Spine Synapse Recycling Endosome
	Molecular Function		GTPase Activator Activity Protein Binding Phospholipid Binding
	Biological Process	Developmental Process	Exocytosis Small GTPase Mediated Signal Transduction Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways			Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: ARHGAP44 SFPQ	4 interactors: CDC42 HN1 RAC1 TRIP10
Entrez ID		51155	9912
HPRD ID		13665	13810
Ensembl ID		ENSG00000189159	ENSG00000006740
Uniprot IDs		Q9H3K0 Q9UK76	A6NCP5 E7ERK8 Q17R89 Q69Z00
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Oxidative Stress-induced Cell Death Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of Circadian Rhythm Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Histone H3 Deacetylation	Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Phosphatidylinositol 3-kinase Activity Regulation Of Lipid Kinase Activity Positive Regulation Of DNA Replication T Cell Costimulation Actin Cytoskeleton Organization Small GTPase Mediated Signal Transduction Actin Filament-based Process Endocytosis Ephrin Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Cell Projection Assembly Positive Regulation Of Cell-substrate Adhesion Regulation Of DNA Replication Epidermal Cell Differentiation Positive Regulation Of DNA Metabolic Process Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Cell Morphogenesis Involved In Differentiation Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Interleukin-23 Production Positive Regulation Of Hair Follicle Cell Proliferation Regulation Of Cell-substrate Adhesion Cytoskeleton Organization Epithelial Cell Development Positive Regulation Of T Cell Activation Cell-cell Junction Organization Actin Filament Branching Engulfment Of Apoptotic Cell Submandibular Salivary Gland Formation Positive Regulation Of Homotypic Cell-cell Adhesion Leukocyte Migration Mast Cell Chemotaxis Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Positive Regulation Of Cell-cell Adhesion Phagocytosis Epidermis Development Fc Receptor Signaling Pathway Wnt Signaling Pathway Positive Regulation Of Cell Projection Organization Immune Response-activating Cell Surface Receptor Signaling Pathway Vesicle-mediated Transport Cell Projection Assembly Regulation Of T Cell Activation Regulation Of Lipid Metabolic Process
Tagcloud ?		100nm 48h 81m anapc13 calm2 carcinogenic diarrheic drawing exhaustive explanation malat1 mapre2 mllt11 molluscs oa okadaic pathologies poisoning positives pttg1 rodents sga shellfish shsy5y ssh subtractive tax1bp1 toxins tumourigenesis
Tagcloud (Difference) ?		100nm 48h 81m anapc13 calm2 carcinogenic diarrheic drawing exhaustive explanation malat1 mapre2 mllt11 molluscs oa okadaic pathologies poisoning positives pttg1 rodents sga shellfish shsy5y ssh subtractive tax1bp1 toxins tumourigenesis
Tagcloud (Intersection) ?