ACOX1 and SLC2A4

Number of citations of the paper that reports this interaction (PMID 16396496)
24

Data Source:
HPRD (in vivo)

		ACOX1	SLC2A4
Gene Name		acyl-CoA oxidase 1, palmitoyl	solute carrier family 2 (facilitated glucose transporter), member 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Mitochondrion Peroxisome Peroxisomal Membrane Peroxisomal Matrix Plasma Membrane Membrane Intracellular Membrane-bounded Organelle	Multivesicular Body Cytosol Plasma Membrane Integral Component Of Plasma Membrane Coated Pit External Side Of Plasma Membrane Endomembrane System Vesicle Membrane Membrane Clathrin-coated Vesicle Trans-Golgi Network Transport Vesicle T-tubule Insulin-responsive Compartment Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Acyl-CoA Dehydrogenase Activity Acyl-CoA Oxidase Activity Receptor Binding Fatty Acid Binding Palmitoyl-CoA Oxidase Activity PDZ Domain Binding Protein N-terminus Binding Flavin Adenine Dinucleotide Binding FAD Binding	Glucose Transmembrane Transporter Activity Protein Binding D-glucose Transmembrane Transporter Activity
	Biological Process	Very Long-chain Fatty Acid Metabolic Process Generation Of Precursor Metabolites And Energy Lipid Metabolic Process Prostaglandin Metabolic Process Spermatogenesis Peroxisome Fission Fatty Acid Oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Unsaturated Fatty Acid Metabolic Process Alpha-linolenic Acid Metabolic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Lipid Homeostasis Positive Regulation Of Cholesterol Homeostasis	Carbohydrate Metabolic Process Hexose Transport Pathogenesis Amylopectin Biosynthetic Process Glucose Transport Cellular Response To Insulin Stimulus Glucose Homeostasis Small Molecule Metabolic Process Response To Ethanol Glucose Import Brown Fat Cell Differentiation Transmembrane Transport Membrane Organization Cellular Response To Hypoxia Cellular Response To Osmotic Stress
Pathways			Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Translocation of GLUT4 to the plasma membrane SLC-mediated transmembrane transport Hexose transport Myoclonic epilepsy of Lafora Transcriptional regulation of white adipocyte differentiation Facilitative Na+-independent glucose transporters Glycogen storage diseases Glucose transport Metabolism of carbohydrates
Drugs
Diseases
GWAS			Birth weight ( 23202124) Metabolite levels ( 22286219)
Protein-Protein Interactions		3 interactors: SCP2 SLC2A4 TYSND1	38 interactors: ACOX1 ACTN1 ACTN4 AKT2 ARF3 ARFIP1 BSG C1QTNF5 CCDC116 CFL1 CTSD DAXX DLD EHD2 ESYT2 FAR1 FKBP10 GAPDH HADH HK2 HSP90AA1 IDH2 KLHL41 LNPEP MAP1S MVP P3H1 P3H4 PDIA6 PRKAR1A PSMD7 RAB7A SERPINH1 SRFBP1 STRN3 UBA52 UBE2I UBE2N
Entrez ID		51	6517
HPRD ID		02030	00688
Ensembl ID		ENSG00000161533	ENSG00000181856
Uniprot IDs		Q15067	P14672 Q05BQ3
PDB IDs
Enriched GO Terms of Interacting Partners?		Lipid Hydroperoxide Transport Amylopectin Biosynthetic Process Positive Regulation Of Intracellular Cholesterol Transport Regulation Of Intracellular Cholesterol Transport Inositol Trisphosphate Biosynthetic Process Regulation Of Lipid Metabolic Process Male Genitalia Morphogenesis Inositol Phosphate Biosynthetic Process Glucose Import Inositol Trisphosphate Metabolic Process Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Alpha-linolenic Acid Metabolic Process Progesterone Biosynthetic Process Regulation Of Fatty Acid Beta-oxidation Genitalia Morphogenesis Positive Regulation Of Cholesterol Transport Progesterone Metabolic Process C21-steroid Hormone Biosynthetic Process Bile Acid Biosynthetic Process Synaptonemal Complex Assembly Synaptonemal Complex Organization Hexose Transmembrane Transport Positive Regulation Of Steroid Metabolic Process C21-steroid Hormone Metabolic Process Cellular Response To Osmotic Stress Male Genitalia Development Membrane Organization Regulation Of Fatty Acid Oxidation Bile Acid Metabolic Process Female Meiotic Division Regulation Of Cholesterol Transport Brown Fat Cell Differentiation Fatty Acid Beta-oxidation Peroxisome Organization Inositol Phosphate Metabolic Process Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Hormone Biosynthetic Process Positive Regulation Of Nuclease Activity Synapsis Carbohydrate Transmembrane Transport Regulation Of Lipid Catabolic Process Homologous Chromosome Segregation Genitalia Development Positive Regulation Of Lipid Transport Male Meiosis Fatty Acid Oxidation Lipid Oxidation Glucose Transport Fatty Acid Catabolic Process Hexose Transport	Generation Of Precursor Metabolites And Energy Catabolic Process Protein Localization To Tight Junction Protein Transport Establishment Of Protein Localization Protein Localization Small Molecule Metabolic Process Organelle Organization Positive Regulation Of Transferase Activity Monocarboxylic Acid Metabolic Process Regulation Of Body Fluid Levels Antigen Processing And Presentation Of Peptide Antigen Protein Targeting Blood Coagulation Hemostasis Pyruvate Metabolic Process Intracellular Protein Transport Oxidation-reduction Process Response To Stress Protein Localization To Cell Junction Glucose Metabolic Process Antigen Processing And Presentation Regulation Of Cellular Protein Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Establishment Of Localization In Cell Protein Polyubiquitination Response To Stimulus Cellular Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Response To Organic Substance Cytoskeleton Organization Protein Localization To Membrane Platelet Degranulation Immune System Process Vesicle-mediated Transport Protein Ubiquitination Regulation Of Protein Metabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Extracellular Matrix Organization Extracellular Structure Organization Collagen Metabolic Process Membrane Organization Actin Cytoskeleton Organization Positive Regulation Of Ligase Activity Intracellular Receptor Signaling Pathway Transport Wound Healing Multicellular Organismal Macromolecule Metabolic Process Protein Metabolic Process Regulation Of Protein Ubiquitination
Tagcloud ?		acsl1 cd36 dgat2 droplet fgf21 gluconeogenic hepatokine ikbke il6 lcfa lcfas med1 monogastrics nrip1 parturition pck1 plin2 ppara ppard prkaa1 pufa rxra saturated scd sfat srebf2 stk11 triacylglycerol ucp2	atp1a2 atp1b2 beef corpus cows diestrus follicle glandular gonadotropin lcl lf luteum manipulated nelore ovulation p4 periovulatory pof preovulatory proestrus receptivity slaughtered slc5a1 washings
Tagcloud (Difference) ?		acsl1 cd36 dgat2 droplet fgf21 gluconeogenic hepatokine ikbke il6 lcfa lcfas med1 monogastrics nrip1 parturition pck1 plin2 ppara ppard prkaa1 pufa rxra saturated scd sfat srebf2 stk11 triacylglycerol ucp2	atp1a2 atp1b2 beef corpus cows diestrus follicle glandular gonadotropin lcl lf luteum manipulated nelore ovulation p4 periovulatory pof preovulatory proestrus receptivity slaughtered slc5a1 washings
Tagcloud (Intersection) ?