ACOX1 and SCP2

Number of citations of the paper that reports this interaction (PMID 10856712)
16

Data Source:
HPRD (in vitro)

		ACOX1	SCP2
Gene Name		acyl-CoA oxidase 1, palmitoyl	sterol carrier protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Mitochondrion Peroxisome Peroxisomal Membrane Peroxisomal Matrix Plasma Membrane Membrane Intracellular Membrane-bounded Organelle	Nucleoplasm Cytoplasm Mitochondrion Peroxisome Peroxisomal Matrix Membrane Intracellular Membrane-bounded Organelle Protein Complex Extracellular Vesicular Exosome
	Molecular Function	Acyl-CoA Dehydrogenase Activity Acyl-CoA Oxidase Activity Receptor Binding Fatty Acid Binding Palmitoyl-CoA Oxidase Activity PDZ Domain Binding Protein N-terminus Binding Flavin Adenine Dinucleotide Binding FAD Binding	Fatty-acyl-CoA Binding Receptor Binding Protein Binding Phosphatidylinositol Transporter Activity Cholesterol Binding Propanoyl-CoA C-acyltransferase Activity Long-chain Fatty Acyl-CoA Binding Oleic Acid Binding
	Biological Process	Very Long-chain Fatty Acid Metabolic Process Generation Of Precursor Metabolites And Energy Lipid Metabolic Process Prostaglandin Metabolic Process Spermatogenesis Peroxisome Fission Fatty Acid Oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Unsaturated Fatty Acid Metabolic Process Alpha-linolenic Acid Metabolic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Lipid Homeostasis Positive Regulation Of Cholesterol Homeostasis	Steroid Biosynthetic Process Bile Acid Biosynthetic Process Progesterone Biosynthetic Process Lipid Transport Peroxisome Organization Bile Acid Metabolic Process Phospholipid Transport Positive Regulation Of Intracellular Cholesterol Transport Inositol Trisphosphate Biosynthetic Process Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Unsaturated Fatty Acid Metabolic Process Alpha-linolenic Acid Metabolic Process Cellular Lipid Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Steroid Metabolic Process Protein Localization To Plasma Membrane Lipid Hydroperoxide Transport
Pathways			Metabolism of lipids and lipoproteins alpha-linolenic acid (ALA) metabolism alpha-linolenic (omega3) and linoleic (omega6) acid metabolism
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: SCP2 SLC2A4 TYSND1	8 interactors: ACAA2 ACOX1 CACNA1A CAV1 EHHADH PEX5 PITPNA TRIP13
Entrez ID		51	6342
HPRD ID		02030	01700
Ensembl ID		ENSG00000161533	ENSG00000116171
Uniprot IDs		Q15067	B2R761 E9PLD1 P22307 Q59HG9
PDB IDs			1QND 2C0L
Enriched GO Terms of Interacting Partners?		Lipid Hydroperoxide Transport Amylopectin Biosynthetic Process Positive Regulation Of Intracellular Cholesterol Transport Regulation Of Intracellular Cholesterol Transport Inositol Trisphosphate Biosynthetic Process Regulation Of Lipid Metabolic Process Male Genitalia Morphogenesis Inositol Phosphate Biosynthetic Process Glucose Import Inositol Trisphosphate Metabolic Process Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Alpha-linolenic Acid Metabolic Process Progesterone Biosynthetic Process Regulation Of Fatty Acid Beta-oxidation Genitalia Morphogenesis Positive Regulation Of Cholesterol Transport Progesterone Metabolic Process C21-steroid Hormone Biosynthetic Process Bile Acid Biosynthetic Process Synaptonemal Complex Assembly Synaptonemal Complex Organization Hexose Transmembrane Transport Positive Regulation Of Steroid Metabolic Process C21-steroid Hormone Metabolic Process Cellular Response To Osmotic Stress Male Genitalia Development Membrane Organization Regulation Of Fatty Acid Oxidation Bile Acid Metabolic Process Female Meiotic Division Regulation Of Cholesterol Transport Brown Fat Cell Differentiation Fatty Acid Beta-oxidation Peroxisome Organization Inositol Phosphate Metabolic Process Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Hormone Biosynthetic Process Positive Regulation Of Nuclease Activity Synapsis Carbohydrate Transmembrane Transport Regulation Of Lipid Catabolic Process Homologous Chromosome Segregation Genitalia Development Positive Regulation Of Lipid Transport Male Meiosis Fatty Acid Oxidation Lipid Oxidation Glucose Transport Fatty Acid Catabolic Process Hexose Transport	Fatty Acid Beta-oxidation Lipid Metabolic Process Fatty Acid Oxidation Lipid Oxidation Fatty Acid Catabolic Process Fatty Acid Metabolic Process Cellular Lipid Metabolic Process Carboxylic Acid Metabolic Process Cellular Lipid Catabolic Process Organic Acid Metabolic Process Monocarboxylic Acid Metabolic Process Small Molecule Metabolic Process Lipid Modification Carboxylic Acid Catabolic Process Very Long-chain Fatty Acid Metabolic Process Lipid Catabolic Process Peroxisome Organization Membrane Organization Mitochondrial Membrane Organization Protein Localization To Membrane Cerebellar Molecular Layer Development Regulation Of Membrane Repolarization During Action Potential Negative Regulation Of Peptidyl-tyrosine Autophosphorylation Negative Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Cellular Response To Oxygen Levels Lipid Homeostasis Membrane Depolarization Vestibular Nucleus Development Negative Regulation Of Protein Homotetramerization Nitric Oxide Homeostasis Neuromuscular Process Oxidation-reduction Process Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Protein Import Into Peroxisome Matrix, Translocation Regulation Of Inward Rectifier Potassium Channel Activity Positive Regulation Of Cholesterol Homeostasis Protein Import Into Peroxisome Matrix, Docking Negative Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Gamma-aminobutyric Acid Secretion Negative Regulation Of Pinocytosis Caveolin-mediated Endocytosis Protein Localization To Basolateral Plasma Membrane Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Acetylcholine Secretion, Neurotransmission Mammary Gland Involution Organelle Organization Cytosolic Calcium Ion Homeostasis
Tagcloud ?		acsl1 cd36 dgat2 droplet fgf21 gluconeogenic hepatokine ikbke il6 lcfa lcfas med1 monogastrics nrip1 parturition pck1 plin2 ppara ppard prkaa1 pufa rxra saturated scd sfat srebf2 stk11 triacylglycerol ucp2	cannabinoid cannabinoids cb chemotactic chemotaxis clone confocal crosstalk cxcl12 cxcr4 cytoskeletal elucidation healing innovative jwh mcf7 metastasis mmtv modulate nt orthotopic p42 p44 possess psychoactive pymt syngenic tumorigenic wound
Tagcloud (Difference) ?		acsl1 cd36 dgat2 droplet fgf21 gluconeogenic hepatokine ikbke il6 lcfa lcfas med1 monogastrics nrip1 parturition pck1 plin2 ppara ppard prkaa1 pufa rxra saturated scd sfat srebf2 stk11 triacylglycerol ucp2	cannabinoid cannabinoids cb chemotactic chemotaxis clone confocal crosstalk cxcl12 cxcr4 cytoskeletal elucidation healing innovative jwh mcf7 metastasis mmtv modulate nt orthotopic p42 p44 possess psychoactive pymt syngenic tumorigenic wound
Tagcloud (Intersection) ?