SLC2A4 and HADH

Number of citations of the paper that reports this interaction (PMID 10068455)
1

Data Source:
HPRD (in vitro, two hybrid)

		SLC2A4	HADH
Gene Name		solute carrier family 2 (facilitated glucose transporter), member 4	hydroxyacyl-CoA dehydrogenase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Multivesicular Body Cytosol Plasma Membrane Integral Component Of Plasma Membrane Coated Pit External Side Of Plasma Membrane Endomembrane System Vesicle Membrane Membrane Clathrin-coated Vesicle Trans-Golgi Network Transport Vesicle T-tubule Insulin-responsive Compartment Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix
	Molecular Function	Glucose Transmembrane Transporter Activity Protein Binding D-glucose Transmembrane Transporter Activity	3-hydroxyacyl-CoA Dehydrogenase Activity NAD+ Binding
	Biological Process	Carbohydrate Metabolic Process Hexose Transport Pathogenesis Amylopectin Biosynthetic Process Glucose Transport Cellular Response To Insulin Stimulus Glucose Homeostasis Small Molecule Metabolic Process Response To Ethanol Glucose Import Brown Fat Cell Differentiation Transmembrane Transport Membrane Organization Cellular Response To Hypoxia Cellular Response To Osmotic Stress	Fatty Acid Beta-oxidation Response To Activity Response To Insulin Response To Drug Cellular Lipid Metabolic Process Small Molecule Metabolic Process Negative Regulation Of Insulin Secretion
Pathways		Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Translocation of GLUT4 to the plasma membrane SLC-mediated transmembrane transport Hexose transport Myoclonic epilepsy of Lafora Transcriptional regulation of white adipocyte differentiation Facilitative Na+-independent glucose transporters Glycogen storage diseases Glucose transport Metabolism of carbohydrates	Fatty acid, triacylglycerol, and ketone body metabolism Beta oxidation of octanoyl-CoA to hexanoyl-CoA Metabolism of lipids and lipoproteins Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA Mitochondrial Fatty Acid Beta-Oxidation Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA mitochondrial fatty acid beta-oxidation of saturated fatty acids Beta oxidation of hexanoyl-CoA to butanoyl-CoA Beta oxidation of butanoyl-CoA to acetyl-CoA
Drugs			NADH Nicotinamide-Adenine-Dinucleotide Acetoacetyl-Coenzyme A 3-Hydroxybutyryl-Coenzyme A
Diseases
GWAS		Birth weight ( 23202124) Metabolite levels ( 22286219)
Protein-Protein Interactions		38 interactors: ACOX1 ACTN1 ACTN4 AKT2 ARF3 ARFIP1 BSG C1QTNF5 CCDC116 CFL1 CTSD DAXX DLD EHD2 ESYT2 FAR1 FKBP10 GAPDH HADH HK2 HSP90AA1 IDH2 KLHL41 LNPEP MAP1S MVP P3H1 P3H4 PDIA6 PRKAR1A PSMD7 RAB7A SERPINH1 SRFBP1 STRN3 UBA52 UBE2I UBE2N	4 interactors: ADH1A APP SLC2A4 STAT1
Entrez ID		6517	3033
HPRD ID		00688	08372
Ensembl ID		ENSG00000181856	ENSG00000138796
Uniprot IDs		P14672 Q05BQ3	E9PF18 Q16836
PDB IDs			1F0Y 1F12 1F14 1F17 1IL0 1LSJ 1LSO 1M75 1M76 2HDH 3HAD 3RQS
Enriched GO Terms of Interacting Partners?		Generation Of Precursor Metabolites And Energy Catabolic Process Protein Localization To Tight Junction Protein Transport Establishment Of Protein Localization Protein Localization Small Molecule Metabolic Process Organelle Organization Positive Regulation Of Transferase Activity Monocarboxylic Acid Metabolic Process Regulation Of Body Fluid Levels Antigen Processing And Presentation Of Peptide Antigen Protein Targeting Blood Coagulation Hemostasis Pyruvate Metabolic Process Intracellular Protein Transport Oxidation-reduction Process Response To Stress Protein Localization To Cell Junction Glucose Metabolic Process Antigen Processing And Presentation Regulation Of Cellular Protein Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Establishment Of Localization In Cell Protein Polyubiquitination Response To Stimulus Cellular Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Response To Organic Substance Cytoskeleton Organization Protein Localization To Membrane Platelet Degranulation Immune System Process Vesicle-mediated Transport Protein Ubiquitination Regulation Of Protein Metabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Extracellular Matrix Organization Extracellular Structure Organization Collagen Metabolic Process Membrane Organization Actin Cytoskeleton Organization Positive Regulation Of Ligase Activity Intracellular Receptor Signaling Pathway Transport Wound Healing Multicellular Organismal Macromolecule Metabolic Process Protein Metabolic Process Regulation Of Protein Ubiquitination	Negative Regulation Of Macrophage Fusion Amylopectin Biosynthetic Process Chemical Homeostasis Negative Regulation By Virus Of Viral Protein Levels In Host Cell Negative Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Synaptic Growth At Neuromuscular Junction Response To Abiotic Stimulus Cellular Response To Insulin Stimulus Collateral Sprouting In Absence Of Injury Negative Regulation Of Nephron Tubule Epithelial Cell Differentiation Metanephric Mesenchymal Cell Proliferation Involved In Metanephros Development Homeostatic Process Collateral Sprouting Axon Midline Choice Point Recognition Metanephric Mesenchymal Cell Differentiation Response To Insulin Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cellular Response To Peptide Hormone Stimulus Negative Regulation Of Syncytium Formation By Plasma Membrane Fusion Axon Choice Point Recognition Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Cellular Response To Peptide Negative Regulation Of Cell Development Alcohol Metabolic Process Glucose Import Neuron Remodeling Mesenchymal Cell Differentiation Involved In Kidney Development Cell Proliferation Involved In Metanephros Development Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Response To Oxidative Stress Cell Differentiation Involved In Metanephros Development Response To Peptide Hormone Cellular Response To Organonitrogen Compound Cellular Response To Interferon-beta Response To Peptide Cell Proliferation Involved In Kidney Development Mesenchymal Cell Proliferation Ethanol Oxidation Metanephric Mesenchyme Development Cellular Copper Ion Homeostasis Response To Interferon-beta Regulation Of Nephron Tubule Epithelial Cell Differentiation Cellular Response To Hormone Stimulus Small Molecule Metabolic Process Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Epithelial Cell Differentiation Involved In Kidney Development JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Regulation Of Response To Interferon-gamma Copper Ion Homeostasis
Tagcloud ?		atp1a2 atp1b2 beef corpus cows diestrus follicle glandular gonadotropin lcl lf luteum manipulated nelore ovulation p4 periovulatory pof preovulatory proestrus receptivity slaughtered slc5a1 washings	aeruginosa brown colorimetric concurrently dehydrogenases dinitrophenylhydrazine easily enantioselective enantioselectivity hadhs harboring herein hplc hydroxyacid hydroxyacids industry isolate isolation ketoacid matches microorganisms oxidation producing pseudomonas quantified spectrophotometric stains throughput true
Tagcloud (Difference) ?		atp1a2 atp1b2 beef corpus cows diestrus follicle glandular gonadotropin lcl lf luteum manipulated nelore ovulation p4 periovulatory pof preovulatory proestrus receptivity slaughtered slc5a1 washings	aeruginosa brown colorimetric concurrently dehydrogenases dinitrophenylhydrazine easily enantioselective enantioselectivity hadhs harboring herein hplc hydroxyacid hydroxyacids industry isolate isolation ketoacid matches microorganisms oxidation producing pseudomonas quantified spectrophotometric stains throughput true
Tagcloud (Intersection) ?