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DYT10 and STXBP1
Number of citations of the paper that reports this interaction (PMID
12519779
)
26
Data Source:
BioGRID
(enzymatic study)
DYT10
STXBP1
Gene Name
dystonia 10
syntaxin binding protein 1
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Mitochondrion
Cytosol
Plasma Membrane
Platelet Alpha Granule
Protein Complex
Extracellular Vesicular Exosome
Molecular Function
SNARE Binding
Syntaxin-1 Binding
Protein Kinase Binding
Protein Domain Specific Binding
Syntaxin Binding
Identical Protein Binding
Poly(A) RNA Binding
Protein N-terminus Binding
Biological Process
Platelet Degranulation
Energy Reserve Metabolic Process
Vesicle Docking Involved In Exocytosis
Synaptic Transmission
Neurotransmitter Secretion
Neuromuscular Synaptic Transmission
Axon Target Recognition
Regulation Of Synaptic Vesicle Priming
Glutamate Secretion
Protein Transport
Synaptic Vesicle Maturation
Regulation Of Synaptic Vesicle Fusion To Presynaptic Membrane
Negative Regulation Of Synaptic Transmission, GABAergic
Regulation Of SNARE Complex Assembly
Negative Regulation Of Neuron Apoptotic Process
Small Molecule Metabolic Process
Positive Regulation Of Calcium Ion-dependent Exocytosis
Regulation Of Insulin Secretion
Protein Stabilization
Long Term Synaptic Depression
Platelet Aggregation
Protein Localization To Plasma Membrane
Pathways
Integration of energy metabolism
Regulation of insulin secretion
Drugs
Diseases
GWAS
Protein-Protein Interactions
14 interactors:
AKAP13
BTG2
CACYBP
CYTH2
DAB2
GRM5
IFRD1
NFE2L2
NOXA1
PARK2
SATB1
SPAG1
STXBP1
XK
27 interactors:
APBA1
APBA2
APP
CDK5
CDK5R1
DOC2A
DOC2B
DYT10
HGS
MAPT
NEFH
NEFM
PLD1
PLD2
PRKCA
PRKCB
PRKCG
SQSTM1
STX11
STX19
STX1A
STX1B
STX2
STX3
SYTL4
TRIM38
USO1
Entrez ID
50818
6812
HPRD ID
04235
Ensembl ID
ENSG00000136854
Uniprot IDs
B7Z1V5
P61764
Q68CM6
PDB IDs
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Cell Death
Regulation Of Cell Death
Positive Regulation Of Metabolic Process
Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Learning
Regulation Of Reactive Oxygen Species Metabolic Process
Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Regulation Of Apoptotic Process
Negative Regulation Of Oxidative Stress-induced Cell Death
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Negative Regulation Of Neuron Apoptotic Process
Muscle Structure Development
Negative Regulation Of Neuron Death
Cell Differentiation
Regulation Of Synaptic Vesicle Transport
Regulation Of Intracellular Signal Transduction
Regulation Of Neuron Apoptotic Process
Regulation Of Cellular Response To Oxidative Stress
Multicellular Organismal Development
Regulation Of Metabolic Process
Negative Regulation Of Apoptotic Signaling Pathway
Negative Regulation Of Signaling
Learning Or Memory
Anatomical Structure Development
Regulation Of Neuron Death
Cognition
Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Mitochondrial Fusion
Adult Somatic Muscle Development
Regulation Of Synaptic Transmission
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Neurotransmitter Secretion
Striated Muscle Tissue Development
Muscle Cell Differentiation
Positive Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Signaling
Muscle Tissue Development
Regulation Of Kinase Activity
System Development
Developmental Process
Positive Regulation Of Macromolecule Biosynthetic Process
Leading Edge Cell Differentiation
Positive Regulation Of Protein Linear Polyubiquitination
Myoblast Fate Determination
Phospholipase C-activating G-protein Coupled Glutamate Receptor Signaling Pathway
Regulation Of Vesicle-mediated Transport
Positive Regulation Of Catalytic Activity
Protein Stabilization
Synaptic Transmission
Synaptic Vesicle Exocytosis
Synaptic Vesicle Fusion To Presynaptic Membrane
Neurotransmitter Secretion
Synaptic Vesicle Transport
Cell-cell Signaling
Regulation Of Neurotransmitter Levels
Establishment Of Localization In Cell
Secretion By Cell
Neurotransmitter Transport
Vesicle Fusion
Establishment Of Vesicle Localization
Vesicle Localization
Secretion
Establishment Of Organelle Localization
Cellular Localization
Exocytosis
Organelle Fusion
Vesicle Docking
Intracellular Transport
Membrane Docking
Organelle Localization
Membrane Fusion
Protein Localization
Regulation Of Exocytosis
Regulation Of Cellular Localization
Protein Transport
Membrane Organization
Establishment Of Protein Localization
Intracellular Protein Transport
Signaling
Transport
Cell Communication
Vesicle Organization
Positive Regulation Of Exocytosis
Vesicle-mediated Transport
Cellular Protein Localization
Regulation Of Vesicle-mediated Transport
Peptidyl-threonine Phosphorylation
Regulation Of Secretion
Axon Cargo Transport
Regulation Of Signaling
Organelle Organization
Positive Regulation Of Secretion
Histone H3-T6 Phosphorylation
Neurofilament Bundle Assembly
Positive Regulation Of Transport
Serine Phosphorylation Of STAT3 Protein
Nervous System Development
Regulation Of Synaptic Vesicle Transport
Tagcloud
?
16p12
2q24
5q14
9q34
aetiology
caln1
cdkl5
cgh
cnv
cnvs
counselling
ehmt1
encephalopathies
encompassing
epileptic
etiological
grin2a
hypsarrhythmia
infantile
intronic
iss
kcnq2
magi2
mef2c
microdeletions
microduplications
scn2a
spasms
xq28
Tagcloud (Difference)
?
16p12
2q24
5q14
9q34
aetiology
caln1
cdkl5
cgh
cnv
cnvs
counselling
ehmt1
encephalopathies
encompassing
epileptic
etiological
grin2a
hypsarrhythmia
infantile
intronic
iss
kcnq2
magi2
mef2c
microdeletions
microduplications
scn2a
spasms
xq28
Tagcloud (Intersection)
?