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DYT10 and DAB2
Number of citations of the paper that reports this interaction (PMID
10542228
)
11
Data Source:
BioGRID
(enzymatic study)
DYT10
DAB2
Gene Name
dystonia 10
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleolus
Lysosomal Membrane
Plasma Membrane
Coated Pit
Focal Adhesion
Apical Plasma Membrane
Clathrin Coat Of Coated Pit
Clathrin-coated Vesicle
Clathrin-coated Vesicle Membrane
Intracellular Membrane-bounded Organelle
Transforming Growth Factor Beta Receptor Homodimeric Complex
Extracellular Vesicular Exosome
Molecular Function
Integrin Binding
Protein Binding
Phosphatidylinositol-4,5-bisphosphate Binding
Protein C-terminus Binding
AP-2 Adaptor Complex Binding
Clathrin Adaptor Activity
Cargo Receptor Activity
SMAD Binding
Biological Process
Cell Morphogenesis Involved In Differentiation
In Utero Embryonic Development
Positive Regulation Of Receptor Recycling
Positive Regulation Of Protein Phosphorylation
Receptor-mediated Endocytosis
Pinocytosis
Apoptotic Process
Integrin-mediated Signaling Pathway
Activation Of JUN Kinase Activity
Endoderm Development
Excretion
Cell Proliferation
Positive Regulation Of Epithelial To Mesenchymal Transition
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Protein Transport
Wnt Signaling Pathway
Myeloid Cell Differentiation
Positive Regulation Of Cell Migration
Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Protein Binding
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Leading Edge Cell Differentiation
Negative Regulation Of Apoptotic Process
Positive Regulation Of Endocytosis
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Clathrin Coat Assembly
Positive Regulation Of SMAD Protein Import Into Nucleus
Negative Regulation Of Androgen Receptor Signaling Pathway
Membrane Organization
Cellular Response To Transforming Growth Factor Beta Stimulus
Negative Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Negative Regulation Of Protein Localization To Plasma Membrane
Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway
Positive Regulation Of Clathrin-mediated Endocytosis
Positive Regulation Of Early Endosome To Late Endosome Transport
Positive Regulation Of Integrin-mediated Signaling Pathway
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Formation of annular gap junctions
Gap junction degradation
Gap junction trafficking and regulation
Gap junction trafficking
Drugs
Diseases
GWAS
Chronic kidney disease (
20383146
)
Pancreatic cancer (
22158540
)
Urate levels (
23263486
)
Protein-Protein Interactions
14 interactors:
AKAP13
BTG2
CACYBP
CYTH2
DAB2
GRM5
IFRD1
NFE2L2
NOXA1
PARK2
SATB1
SPAG1
STXBP1
XK
37 interactors:
AP2M1
APLP1
APLP2
APP
ATXN1L
AXIN1
CDC16
CDK1
CSK
DAB2IP
DIP2A
DVL1
DVL3
DYT10
FCHO2
FGR
GRB2
INPP5D
ITGB3
ITGB5
ITSN1
LDLR
LRP1
LRP2
MIB1
MYO6
NECAP1
PIN1
PRKCB
PRKCD
PRKCG
SMAD2
SMAD3
SMURF2
SRC
TGFBR1
TGFBR2
Entrez ID
50818
1601
HPRD ID
03139
Ensembl ID
ENSG00000153071
Uniprot IDs
B2RAW0
P98082
PDB IDs
2LSW
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Cell Death
Regulation Of Cell Death
Positive Regulation Of Metabolic Process
Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Learning
Regulation Of Reactive Oxygen Species Metabolic Process
Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Regulation Of Apoptotic Process
Negative Regulation Of Oxidative Stress-induced Cell Death
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Negative Regulation Of Neuron Apoptotic Process
Muscle Structure Development
Negative Regulation Of Neuron Death
Cell Differentiation
Regulation Of Synaptic Vesicle Transport
Regulation Of Intracellular Signal Transduction
Regulation Of Neuron Apoptotic Process
Regulation Of Cellular Response To Oxidative Stress
Multicellular Organismal Development
Regulation Of Metabolic Process
Negative Regulation Of Apoptotic Signaling Pathway
Negative Regulation Of Signaling
Learning Or Memory
Anatomical Structure Development
Regulation Of Neuron Death
Cognition
Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Mitochondrial Fusion
Adult Somatic Muscle Development
Regulation Of Synaptic Transmission
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Neurotransmitter Secretion
Striated Muscle Tissue Development
Muscle Cell Differentiation
Positive Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Signaling
Muscle Tissue Development
Regulation Of Kinase Activity
System Development
Developmental Process
Positive Regulation Of Macromolecule Biosynthetic Process
Leading Edge Cell Differentiation
Positive Regulation Of Protein Linear Polyubiquitination
Myoblast Fate Determination
Phospholipase C-activating G-protein Coupled Glutamate Receptor Signaling Pathway
Regulation Of Vesicle-mediated Transport
Positive Regulation Of Catalytic Activity
Protein Stabilization
Cell Surface Receptor Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Endocytosis
Signal Transduction
Regulation Of Phosphorus Metabolic Process
Negative Regulation Of Signal Transduction
Signaling
Cell Communication
Regulation Of Signaling
Negative Regulation Of Signaling
Regulation Of Signal Transduction
Cellular Response To Growth Factor Stimulus
Regulation Of Phosphorylation
Response To Growth Factor
Regulation Of Cellular Response To Growth Factor Stimulus
Cellular Response To Organic Substance
Positive Regulation Of Cellular Metabolic Process
Cellular Response To Stimulus
Developmental Process
Positive Regulation Of Signal Transduction
Response To Wounding
Regulation Of Protein Phosphorylation
Regulation Of Protein Kinase Activity
Anatomical Structure Morphogenesis
Multicellular Organismal Development
Wound Healing
Regulation Of Protein Metabolic Process
Regulation Of Kinase Activity
Regulation Of Cellular Protein Metabolic Process
Vesicle-mediated Transport
Positive Regulation Of Catalytic Activity
Regulation Of Catalytic Activity
Positive Regulation Of Transferase Activity
Positive Regulation Of Cellular Protein Metabolic Process
Response To Organic Substance
Nervous System Development
Embryonic Morphogenesis
System Development
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Metabolic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Cellular Metabolic Process
Regulation Of Metabolic Process
Response To Stimulus
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Intracellular Signal Transduction
Immune System Process
Anatomical Structure Development
Platelet Activation
Tagcloud
?
associations
blotting
ccnd1
ccnd2
dact1
day
detect
displayed
expressions
fosl1
increasing
jun
mean
pathway
pcr
placenta
play
promoting
real
relationship
signaling
spss
target
tissue
tissues
trend
value
western
wnt
Tagcloud (Difference)
?
associations
blotting
ccnd1
ccnd2
dact1
day
detect
displayed
expressions
fosl1
increasing
jun
mean
pathway
pcr
placenta
play
promoting
real
relationship
signaling
spss
target
tissue
tissues
trend
value
western
wnt
Tagcloud (Intersection)
?