DYT10 and NOXA1

Number of citations of the paper that reports this interaction (PMID 20110267)
11

Data Source:
BioGRID (enzymatic study)

		DYT10	NOXA1
Gene Name		dystonia 10	NADPH oxidase activator 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Cytoplasm NADPH Oxidase Complex
	Molecular Function		Protein Binding Superoxide-generating NADPH Oxidase Activator Activity SH3 Domain Binding Enzyme Binding Rac GTPase Binding
	Biological Process		Superoxide Metabolic Process Regulation Of Hydrogen Peroxide Metabolic Process Positive Regulation Of Catalytic Activity Regulation Of Respiratory Burst
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: AKAP13 BTG2 CACYBP CYTH2 DAB2 GRM5 IFRD1 NFE2L2 NOXA1 PARK2 SATB1 SPAG1 STXBP1 XK	12 interactors: CACNA1A DYT10 EP300 MAPK1 MAPK11 NCF1 NOXO1 PRKACA PRKCG RAC1 RAC2 RIMBP3
Entrez ID		50818	10811
HPRD ID			17644
Ensembl ID			ENSG00000188747
Uniprot IDs			Q86UR1
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cell Death Regulation Of Cell Death Positive Regulation Of Metabolic Process Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Learning Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Apoptotic Process Negative Regulation Of Oxidative Stress-induced Cell Death Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Neuron Apoptotic Process Muscle Structure Development Negative Regulation Of Neuron Death Cell Differentiation Regulation Of Synaptic Vesicle Transport Regulation Of Intracellular Signal Transduction Regulation Of Neuron Apoptotic Process Regulation Of Cellular Response To Oxidative Stress Multicellular Organismal Development Regulation Of Metabolic Process Negative Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Signaling Learning Or Memory Anatomical Structure Development Regulation Of Neuron Death Cognition Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Mitochondrial Fusion Adult Somatic Muscle Development Regulation Of Synaptic Transmission Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Neurotransmitter Secretion Striated Muscle Tissue Development Muscle Cell Differentiation Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Signaling Muscle Tissue Development Regulation Of Kinase Activity System Development Developmental Process Positive Regulation Of Macromolecule Biosynthetic Process Leading Edge Cell Differentiation Positive Regulation Of Protein Linear Polyubiquitination Myoblast Fate Determination Phospholipase C-activating G-protein Coupled Glutamate Receptor Signaling Pathway Regulation Of Vesicle-mediated Transport Positive Regulation Of Catalytic Activity Protein Stabilization	Vascular Endothelial Growth Factor Receptor Signaling Pathway Innate Immune Response Regulation Of Hydrogen Peroxide Metabolic Process Platelet Activation Regulation Of Respiratory Burst Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Surface Receptor Signaling Pathway Immune Response Defense Response Response To Stress Blood Coagulation Hemostasis Enzyme Linked Receptor Protein Signaling Pathway Cell Death Death Intracellular Signal Transduction Regulation Of Body Fluid Levels Cellular Response To Growth Factor Stimulus Wound Healing Response To Growth Factor Cell Activation Response To Wounding Immune System Process Positive Regulation Of Cell Migration Nervous System Development Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Signal Transduction Positive Regulation Of Chemotaxis Positive Regulation Of Catalytic Activity Positive Regulation Of Lamellipodium Assembly Positive Regulation Of Immune System Process Positive Regulation Of Behavior Signaling Positive Regulation Of Lamellipodium Organization Regulation Of Chemotaxis Cell Communication Apoptotic Process Programmed Cell Death Regulation Of Reactive Oxygen Species Metabolic Process Response To External Stimulus Positive Regulation Of Kinase Activity Epidermal Growth Factor Receptor Signaling Pathway Cellular Response To Organic Substance Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Neutrophil Chemotaxis
Tagcloud ?			accumulates agonistic anion capability conventionally dr4 dr5 eventual fc fused jurkat kd548 kringle nadph negligible nox1 noxo1 proapoptotic rac1 recombinantly recruit recruiting rfk riboflavin ros stabilizes tradd traf2 trail
Tagcloud (Difference) ?			accumulates agonistic anion capability conventionally dr4 dr5 eventual fc fused jurkat kd548 kringle nadph negligible nox1 noxo1 proapoptotic rac1 recombinantly recruit recruiting rfk riboflavin ros stabilizes tradd traf2 trail
Tagcloud (Intersection) ?