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P4HB and P4HA3
Number of citations of the paper that reports this interaction (PubMedID
14500733
)
0
Data Source:
HPRD
(in vitro, in vivo)
P4HB
P4HA3
Description
prolyl 4-hydroxylase subunit beta
prolyl 4-hydroxylase subunit alpha 3
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Endoplasmic Reticulum
Endoplasmic Reticulum Lumen
Endoplasmic Reticulum-Golgi Intermediate Compartment
Cytosol
Cytoskeleton
Plasma Membrane
Focal Adhesion
External Side Of Plasma Membrane
Membrane
Procollagen-proline 4-dioxygenase Complex
Lamellipodium
Protein-containing Complex
Endoplasmic Reticulum Chaperone Complex
Melanosome
Extracellular Exosome
Endoplasmic Reticulum
Endoplasmic Reticulum Lumen
Molecular Function
RNA Binding
Protein Disulfide Isomerase Activity
Actin Binding
Procollagen-proline 4-dioxygenase Activity
Integrin Binding
Protein Binding
Protein-disulfide Reductase Activity
Isomerase Activity
Thiol Oxidase Activity
Enzyme Binding
Protein-containing Complex Binding
Protein Heterodimerization Activity
Procollagen-proline 4-dioxygenase Activity
Iron Ion Binding
Protein Binding
Oxidoreductase Activity
Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen
L-ascorbic Acid Binding
Metal Ion Binding
Dioxygenase Activity
Biological Process
Protein Folding
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline
Insulin Processing
Protein Folding In Endoplasmic Reticulum
Response To Endoplasmic Reticulum Stress
Interleukin-12-mediated Signaling Pathway
Interleukin-23-mediated Signaling Pathway
Positive Regulation Of Cell Adhesion
Positive Regulation Of Viral Entry Into Host Cell
Cellular Response To Hypoxia
Cellular Response To Interleukin-7
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of T Cell Migration
Collagen Fibril Organization
Pathways
Collagen biosynthesis and modifying enzymes
Insulin processing
Detoxification of Reactive Oxygen Species
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Hedgehog ligand biogenesis
VLDL assembly
Post-translational protein phosphorylation
Chylomicron assembly
LDL remodeling
Interleukin-12 signaling
Interleukin-23 signaling
Collagen biosynthesis and modifying enzymes
Drugs
Zinc
Ribostamycin
Copper
Artenimol
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Diseases
GWAS
Hippocampal atrophy (
25625606
)
Interacting Genes
54 interacting genes:
CD1D
CHCHD2
CNNM3
COL10A1
COL1A1
COL1A2
CSNK2A2
CST2
EIF2S1
ENO1
ERN1
ERO1A
ERO1B
ESR1
FAM20C
FEZ1
FNDC3B
FZD10
GARIN6
GRN
HNRNPD
ITGB3
KLHL42
KRTAP12-3
KRTAP13-2
KRTAP4-11
KRTAP5-9
KRTAP6-3
KRTAP9-8
LCE1B
LCE2D
LCE4A
LCN2
LGALS9
LINC00839
LRFN4
NECTIN2
NOL4
NTM
ODF1
OGT
P4HA2
P4HA3
PDE4B
PLCXD3
PRNP
PTN
SUMO2
TG
TGFB1
UBQLN1
VWF
YWHAG
ZNF69
49 interacting genes:
ACOT8
ADRA2C
ANAPC11
ATN1
B9D2
BAG4
BLOC1S2
C1QTNF2
CERCAM
CKMT2
CLPP
CT55
CTAG1A
CTAG1B
CTNNBIP1
DTNBP1
FAM136A
FIRRM
GGA3
GPSM3
HGS
KRTAP19-5
KRTAP6-1
KRTAP8-1
LRP2BP
MAGEA2
MAGEA2B
MAGEC2
MCCD1
MEOX2
MSRA
NDN
NICN1
NUTM1
OIP5
P4HB
PROP1
PSMB4
RBFOX1
RUSC1
SCARA5
SERTAD1
SERTAD3
STMN3
TLE5
TOX2
VPS37C
WDR62
ZC3H12A
Entrez ID
5034
283208
HPRD ID
07181
16413
Ensembl ID
ENSG00000185624
ENSG00000149380
Uniprot IDs
A0A024R8S5
P07237
Q7Z4N8
PDB IDs
1BJX
1MEK
1X5C
2BJX
2K18
3BJ5
3UEM
4EKZ
4EL1
4JU5
6I7S
7ZSC
8EOJ
8GDY
Enriched GO Terms of Interacting Partners
?
Protease Binding
Identical Protein Binding
Endoplasmic Reticulum Lumen
Collagen Type I Trimer
Intermediate Filament
Cellular Response To Oxygen-containing Compound
Protein Binding
Extracellular Space
Collagen Fibril Organization
Cellular Response To Glucose Stimulus
Response To Amino Acid
Response To Monosaccharide
Tissue Development
Response To Kainic Acid
Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity
Keratinization
Cellular Response To Carbohydrate Stimulus
Procollagen-proline 4-dioxygenase Activity
Regulation Of Calcium Ion Transmembrane Transport
Regulation Of Response To Tumor Cell
Extracellular Matrix Organization
Extracellular Structure Organization
Response To Oxidative Stress
Thiol Oxidase Activity
Response To Carbohydrate
Intracellular Glucose Homeostasis
Regulation Of Monoatomic Cation Transmembrane Transport
Regulation Of Proteolysis
Odontoblast Differentiation
Biomineral Tissue Development
Keratin Filament
Extracellular Matrix Structural Constituent Conferring Tensile Strength
Regulation Of Leukocyte Mediated Cytotoxicity
Cellular Response To Growth Factor Stimulus
Negative Regulation Of Innate Immune Response
Regulation Of Monoatomic Ion Transmembrane Transport
Response To Xenobiotic Stimulus
Fibrillar Collagen Trimer
Positive Regulation Of Axon Regeneration
Regulation Of Endothelial Cell Migration
Regulation Of Lymphocyte Mediated Immunity
Carbohydrate Homeostasis
Response To Estradiol
Glucose Homeostasis
Negative Regulation Of Translational Initiation
Negative Regulation Of Leukocyte Activation
Regulation Of Innate Immune Response
Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains
Response To Growth Factor
Positive Regulation Of Proteolysis
Protein Binding
Positive Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Ubiquitin-protein Transferase Activity
Negative Regulation Of Protein Acetylation
Gamma-tubulin Binding
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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