P4HA3 and C1QTNF2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		P4HA3	C1QTNF2
Description		prolyl 4-hydroxylase subunit alpha 3	C1q and TNF related 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen	Extracellular Region Collagen Trimer
	Molecular Function	Procollagen-proline 4-dioxygenase Activity Iron Ion Binding Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen L-ascorbic Acid Binding Metal Ion Binding Dioxygenase Activity	Protein Binding
	Biological Process	Collagen Fibril Organization	Regulation Of Lipid Metabolic Process
Pathways		Collagen biosynthesis and modifying enzymes
Drugs
Diseases
GWAS		Hippocampal atrophy ( 25625606)	Weight loss (gastric bypass surgery) ( 23643386)
Interacting Genes		49 interacting genes: ACOT8 ADRA2C ANAPC11 ATN1 B9D2 BAG4 BLOC1S2 C1QTNF2 CERCAM CKMT2 CLPP CT55 CTAG1A CTAG1B CTNNBIP1 DTNBP1 FAM136A FIRRM GGA3 GPSM3 HGS KRTAP19-5 KRTAP6-1 KRTAP8-1 LRP2BP MAGEA2 MAGEA2B MAGEC2 MCCD1 MEOX2 MSRA NDN NICN1 NUTM1 OIP5 P4HB PROP1 PSMB4 RBFOX1 RUSC1 SCARA5 SERTAD1 SERTAD3 STMN3 TLE5 TOX2 VPS37C WDR62 ZC3H12A	24 interacting genes: AIRIM ANKRD11 BANP CHIC2 GPANK1 HPCA HPCAL1 KCNIP3 KLHL12 LCK LGALS14 MTX2 NCALD NCS1 NOL4 P4HA3 PHOSPHO2 TCEANC TIMM8A TRIM54 UBQLN1 UBQLN2 USP20 VSNL1
Entrez ID		283208	114898
HPRD ID		16413	12715
Ensembl ID		ENSG00000149380	ENSG00000145861
Uniprot IDs		Q7Z4N8	A0A499FIM1 Q9BXJ5
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Positive Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Protein Acetylation Gamma-tubulin Binding
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