P4HA3 and ZC3H12A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		P4HA3	ZC3H12A
Gene Name		prolyl 4-hydroxylase, alpha polypeptide III	zinc finger CCCH-type containing 12A
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Lumen	Nucleoplasm Cytoplasm Plasma Membrane
	Molecular Function	Procollagen-proline 4-dioxygenase Activity Iron Ion Binding Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen L-ascorbic Acid Binding	Endonuclease Activity Protein Binding Metal Ion Binding
	Biological Process	Peptidyl-proline Hydroxylation Oxidation-reduction Process	Angiogenesis Apoptotic Process Positive Regulation Of Autophagy Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Lipid Storage Cell Differentiation Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Macrophage Activation Negative Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Fat Cell Differentiation Cellular Response To Lipopolysaccharide Nucleic Acid Phosphodiester Bond Hydrolysis Positive Regulation Of Reactive Oxygen Species Metabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: DTNBP1 HGS MAGEA2B MAGEC2 MEOX2 NDN NUTM1 P4HB SERTAD1 WDR62 ZC3H12A	13 interactors: AHSP AIMP2 BTRC CYFIP2 EP300 IKBKG IRAK2 KPNA2 P4HA3 SHBG SMAD3 TANK UBC
Entrez ID		283208	80149
HPRD ID		16413	08021
Ensembl ID		ENSG00000149380	ENSG00000163874
Uniprot IDs		B4DUD3 Q7Z4N8	Q5D1E8
PDB IDs			3V32 3V33 3V34
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Gene Expression Positive Regulation Of Protein Ubiquitination Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Somite Specification	I-kappaB Kinase/NF-kappaB Signaling TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Viral Process Toll-like Receptor Signaling Pathway Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Pattern Recognition Receptor Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Innate Immune Response-activating Signal Transduction Regulation Of Protein Stability Activation Of Innate Immune Response Positive Regulation Of Protein Metabolic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Immune Response Regulation Of Cellular Protein Metabolic Process Innate Immune Response Positive Regulation Of Innate Immune Response Toll-like Receptor 5 Signaling Pathway Regulation Of Immune Response Immune Response-regulating Signaling Pathway Toll-like Receptor 10 Signaling Pathway Immune System Process Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Protein Metabolic Process Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Apoptotic Process MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Innate Immune Response Programmed Cell Death Cell Death Death Positive Regulation Of Type I Interferon Production JNK Cascade Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Immune Response Protein Stabilization Regulation Of Type I Interferon Production Regulation Of Immune System Process Positive Regulation Of Cytokine Production Stress-activated MAPK Cascade G2/M Transition Of Mitotic Cell Cycle Stress-activated Protein Kinase Signaling Cascade Defense Response
Tagcloud ?			attached attenuating cascade ccch chains chemotactic consequences consistently deleterious deubiquitinase deubiquitination elucidated feedback finger genotoxic kappab linear mcpip1 mediating monocyte nemo polyubiquitin promotion serves signalling terminated ubiquitylation uncontrolled usp10
Tagcloud (Difference) ?			attached attenuating cascade ccch chains chemotactic consequences consistently deleterious deubiquitinase deubiquitination elucidated feedback finger genotoxic kappab linear mcpip1 mediating monocyte nemo polyubiquitin promotion serves signalling terminated ubiquitylation uncontrolled usp10
Tagcloud (Intersection) ?